The exploration of the human proteome has revealed many uncharacterized proteins with very interesting distributions in tissues and cells. Among them are many receptor proteins with unknown functions and predominant expression in the brain, including the orphan receptor GPR151...Read more

In this movie Professor Tomas Hökfelt (Karolinska Institutet) takes you on a journey to the areas of the brain affected by Alzheimer's disease...Read more

Cilia and flagella are fascinating organelles that can be seen as thin membrane-bound projections extending from the body of various cell types. Most well-known are the flagella of sperm cells and the motile cilia that are present in epithelial cells of the lungs and fallopian tubes, as well as ependymal cells of the brain ventricles. These types of cilia mediate movement. However, there is a third type of cilia, which are non-motile and present in most human cell types, referred to as primary cilia...Read more

Light-sheet microscopy has been used to visualize the 3-D anatomy of one of our smallest and most beautiful organs, the inner ear...Read more

This month we will look into a protein expressed in testis called lamin B receptor (LBR). The analysis was performed with the new multiplex immunohistochemistry technique, which allowed us to characterize when and where proteins are expressed during spermatogenesis - the development of sperm. More in depth information about the technique can be found here!..Read more