News ArticlesMultiplex tissue image of the month - NES in kidneyThe intermediate filament protein nestin (gene: NES) is highlighted in kidney through multiplex immunohistochemistry (mIHC/IF)...Read more Building a high-resolution map of proteins in spermSperm cells are highly specialized for their function in reproduction and have a unique structure among the human cell types. Similarly, the repertoire of proteins that are present in sperm comprise many cell-type specific components. Researchers affiliated with the Human Protein Atlas have started to map proteins in human sperm using immunofluorescence and confocal microscopy to complement and further build on the comprehensive studies of the sperm proteome that so far mainly have been performed using mass spectrometry. This new approach gives a detailed view of the presence and subcellular localization of proteins in sperm, with single-cell resolution...Read more Multiplex tissue image of the month - SOX9 in testisThe localization of SOX9 in the nucleus of sertoli cells in testis is visualized with multiplex immunohistochemistry (mIHC/IF)...Read more Multiplex tissue image of the month - CIBAR2 in bronchusThe sub-ciliary localization of CIBAR2 in ciliated epithelium of the bronchus is visualized by multiplex immunohistochemistry (mIHC/IF)...Read more CFAP300 - A new standard marker for cilia?With the recent release of version 24 of the Human Protein Atlas we provide a detailed map of 654 proteins that localize to a small, but important organelle, called the primary cilium. This tiny protrusion is present on most human cell types and serves as a cellular antenna, providing a compartment that is optimal for carefully sensing, transducing and relaying information from the extracellular environment...Read more |