The image of the month is a fluorescent antibody-based display of the glomerulus; the main filtrating unit within the kidney generated in the HPA group in Uppsala. The image is a result of a multiplex immunohistochemistry staining, where the podocyte protein podocin (gene: NPHS2) and five other proteins specific to different main structures within the kidney were stained and visualized through fluorescently tagged antibodies...Read more

This month we will look into a protein expressed in testis called lamin B receptor (LBR). The analysis was performed with the new multiplex immunohistochemistry technique, which allowed us to characterize when and where proteins are expressed during spermatogenesis - the development of sperm. More in depth information about the technique can be found here!..Read more

To fold or to degrade? Proteins have to be folded to its native structure in order to perform its designated tasks and a failure to do so leads to deleterious effects. Chaperones as the name suggest prevents improper interactions and ensures proper functioning of the proteome...Read more

The winners of the 2019 Nobel Prize in Physiology or Medicine were announced here in Stockholm last week. William G. Kaelin Jr., Sir Peter J. Ratcliffe and Gregg L. Semenza were jointly awarded for their discoveries of how cells sense and adapt to oxygen availability...Read more

A bit more than two decades ago, the first Diablo game was released to the world. A game about a lone hero tasked with bringing down Diablo, one of the lords of Hell. This month we highlight a namesake to this hellish lord of terror, the protein DIABLO...Read more