News ArticlesThe circulating proteome - developments, challenges, and trendsIn an article in the Journal of Proteome Research representatives of HUPO's Human Plasma Proteome Project (HPPP), including several HPA affiliated researchers, present the current progress in the study and mapping of the circulating proteome and discuss how updates of proteomics methods, emerging technologies, and investigations of proteoforms and protein networks can impact the understanding of the proteins circulating in blood...Read more Multiplex tissue image of the month - NES in kidneyThe intermediate filament protein nestin (gene: NES) is highlighted in kidney through multiplex immunohistochemistry (mIHC/IF)...Read more Building a high-resolution map of proteins in spermSperm cells are highly specialized for their function in reproduction and have a unique structure among the human cell types. Similarly, the repertoire of proteins that are present in sperm comprise many cell-type specific components. Researchers affiliated with the Human Protein Atlas have started to map proteins in human sperm using immunofluorescence and confocal microscopy to complement and further build on the comprehensive studies of the sperm proteome that so far mainly have been performed using mass spectrometry. This new approach gives a detailed view of the presence and subcellular localization of proteins in sperm, with single-cell resolution...Read more Festival of Genomics & BiodataThe Festival of Genomics & Biodata is UK's largest and the world's fastest growing life sciences event. This year in London HPA affiliated professor Jochen Schwenk was there to present his research on using blood proteomes for molecular health monitoring...Read more HPA Tissue resource for Young MindsAn article about the HPA has been published in the magazine Frontiers for Young Minds, explaining the Atlas's purpose and work in simple, engaging language. The magazine is aimed at children and teenagers, but anyone curious about how scientists map cells and tissues in the human body will find the article informative...Read more |