Breast cancer is the most common cancer among women worldwide with more than 2 million new cases diagnosed each year. The cancer develops in the mammary gland with the most common forms being adenocarcinomas arising from the epithelial cells that line the milk ducts or the milk-producing lobules. Among these invasive ductal carcinoma (IDC) is the most common type and accounts for around 80% of the cases...Read more

T cells are central drivers of inflammation across autoimmune and inflammatory diseases, yet current therapies inadequately target pathogenic T-cell pathways, limiting durable disease control. In a recent study published in Signal Transduction and Targeted Therapy, a team led by Thomas Helleday and Theodora Manolakou, identified a novel, targetable transcriptional-metabolic axis that sustains inflammatory T-cell responses. In an interview by Gustav Ceder, Helleday discusses the novel findings and ongoing lines of research...Read more

In this episode of Proteins Unfolded Evelina Sjöstedt, head of Single cell analysis at the Human Protein Atlas, joins the hosts PhD students Andrea Villanueva Raisman and Emilio Skarwan to explore the transcriptome, the bridge between our static DNA and active proteins...Read more

In the Episode 82 of of the Proteomics show podcast series "Alt Proteomics" HPA researcher Dr Cecilia Lindskog talks about the importance of proteomics data integration together with the hosts Benjamin Neely and Ben Orsburn...Read more

In the new release version 25.1 of the Human Protein Atlas, a major dataset based on Deep Visual Proteomics has been integrated in the Single cell Resource to provide mass-spectrometry based proteomics at an unprecedented resolution for a large number of cell types and tissues...Read more