Expression of GAPDH in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 1341.93
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

1166.2

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	5907.3
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	3572.2
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	2744.4
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	2720.1
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	2605.0
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	2428.4
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	2327.1
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	2095.8
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	1975.2
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	1917.7
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	1912.8
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	1856.5
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	1843.1
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	1748.3
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	1705.9
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	1705.4
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	1698.5
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	1640.9
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	1626.6
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	1608.3
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	1594.2
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	1590.7
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	1587.3
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	1586.4
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	1574.3
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	1557.3
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	1544.3
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	1529.0
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	1505.1
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	1497.0
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	1472.9
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	1458.1
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	1452.9
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	1450.8
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	1426.4
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	1426.4
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	1396.1
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	1396.0
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	1395.7
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	1381.9
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	1376.9
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	1354.4
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	1348.2
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	1335.6
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	1328.2
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	1321.1
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	1300.6
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	1295.1
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	1291.0
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	1277.0
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	1269.7
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	1261.6
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	1257.5
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	1228.5
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	1228.1
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	1214.6
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	1213.5
TCGA-CL-4957-01A	79 years, female, dead, 425 days	1207.5
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	1207.2
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	1190.6
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	1189.1
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	1187.4
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	1185.9
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	1182.2
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	1180.4
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	1168.3
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	1165.9
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	1161.9
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	1139.9
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	1138.2
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	1122.2
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	1119.1
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	1115.9
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	1110.4
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	1104.2
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	1080.4
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	1055.4
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	1032.6
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	1023.8
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	1019.9
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	1019.8
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	1019.0
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	999.7
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	996.6
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	994.2
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	991.8
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	982.5
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	980.1
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	969.9
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	966.1
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	945.2
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	945.1
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	942.3
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	934.5
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	932.1
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	927.3
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	921.1
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	920.2
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	917.1
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	911.9
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	901.4
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	899.4
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	894.5
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	892.9
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	890.4
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	886.0
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	885.7
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	879.0
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	873.8
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	873.0
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	865.7
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	863.6
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	861.4
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	858.8
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	854.6
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	854.3
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	850.6
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	848.8
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	842.4
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	840.2
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	829.5
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	829.3
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	824.9
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	816.4
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	778.5
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	775.4
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	771.7
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	768.9
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	746.3
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	731.1
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	726.4
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	720.3
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	717.5
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	709.1
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	706.5
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	680.2
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	671.0
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	660.9
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	641.1
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	639.0
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	634.6
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	632.2
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	631.8
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	623.9
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	618.5
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	597.4
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	596.2
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	586.8
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	574.9
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	574.6
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	571.7
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	565.6
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	558.0
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	544.8
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	508.7
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	471.3
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	452.7
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	449.9
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	406.4
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