Cell type atlas - TAF9 - The Human Protein Atlas

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TAF9

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	TAF9
Gene descriptionⁱ Full gene name according to HGNC.	TATA-box binding protein associated factor 9
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	8

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Late spermatids, Early spermatids)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Late spermatids, Early spermatids)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	18 NX
Lung	18 NX

Alveolar cells type 2	31 NX
Lung	31 NX

B-cells	51 NX
Liver	81 NX
Colon	46 NX
Kidney	31 NX

Basal glandular cells	138 NX
Prostate	138 NX

Basal keratinocytes	155 NX
Skin	155 NX

Bipolar cells	21 NX
Eye	21 NX

Cardiomyocytes	61 NX
Heart muscle	61 NX

Cholangiocytes	43 NX
Liver	43 NX

Ciliated cells	34 NX
Lung	34 NX

Club cells	32 NX
Lung	32 NX

Collecting duct cells	23 NX
Kidney	23 NX

Cone photoreceptor cells	14 NX
Eye	14 NX

Cytotrophoblasts	102 NX
Placenta	102 NX

Distal tubular cells	76 NX
Kidney	76 NX

Ductal cells	63 NX
Pancreas	63 NX

Early spermatids	444 NX
Testis	444 NX

Endothelial cells	55 NX
Skin	105 NX
Prostate	80 NX
Placenta	73 NX
Pancreas	65 NX
Testis	55 NX
Eye	48 NX
Heart muscle	47 NX
Liver	34 NX
Lung	32 NX

Enterocytes	37 NX
Small intestine	42 NX
Rectum	32 NX
Colon	25 NX

Erythroid cells	23 NX
Liver	23 NX

Exocrine glandular cells	70 NX
Pancreas	70 NX

Extravillous trophoblasts	134 NX
Placenta	134 NX

Fibroblasts	65 NX
Skin	96 NX
Prostate	65 NX
Placenta	63 NX
Heart muscle	54 NX
Lung	43 NX

Glandular cells	69 NX
Prostate	69 NX

Granulocytes	37 NX
Lung	47 NX
Colon	28 NX

Hepatocytes	41 NX
Liver	41 NX

Hofbauer cells	94 NX
Placenta	94 NX

Horizontal cells	19 NX
Eye	19 NX

Intestinal endocrine cells	30 NX
Rectum	42 NX
Colon	17 NX

Ito cells	34 NX
Liver	34 NX

Kupffer cells	41 NX
Liver	41 NX

Late spermatids	627 NX
Testis	627 NX

Leydig cells	60 NX
Testis	60 NX

Macrophages	61 NX
Prostate	92 NX
Pancreas	80 NX
Skin	77 NX
Kidney	61 NX
Testis	59 NX
Lung	36 NX

Melanocytes	95 NX
Skin	95 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	53 NX
Pancreas	53 NX

Mucus-secreting cells	54 NX
Rectum	58 NX
Small intestine	40 NX
Colon	32 NX

Muller glia cells	24 NX
Eye	24 NX

Pancreatic endocrine cells	77 NX
Pancreas	77 NX

Paneth cells	32 NX
Rectum	50 NX
Small intestine	32 NX
Colon	20 NX

Peritubular cells	32 NX
Testis	32 NX

Proximal tubular cells	67 NX
Kidney	67 NX

Rod photoreceptor cells	33 NX
Eye	33 NX

Sertoli cells	32 NX
Testis	32 NX

Smooth muscle cells	94 NX
Skin	136 NX
Pancreas	104 NX
Prostate	73 NX
Heart muscle	48 NX

Spermatocytes	329 NX
Testis	329 NX

Spermatogonia	66 NX
Testis	66 NX

Suprabasal keratinocytes	143 NX
Skin	143 NX

Syncytiotrophoblasts	87 NX
Placenta	87 NX

T-cells	36 NX
Prostate	92 NX
Skin	74 NX
Kidney	62 NX
Lung	45 NX
Liver	35 NX
Colon	33 NX

Undifferentiated cells	61 NX
Small intestine	83 NX
Rectum	61 NX
Colon	48 NX

Urothelial cells	136 NX
Prostate	136 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.