Cell type atlas - CD24 - The Human Protein Atlas

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CD24

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	CD24
Gene descriptionⁱ Full gene name according to HGNC.	CD24 molecule
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	7

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Exocrine glandular cells, Pancreatic endocrine cells, Distal tubular cells)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Group enriched (eosinophil, memory B-cell, naive B-cell)
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in some
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (NTERA-2, RPTEC TERT1, SK-BR-3)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Exocrine glandular cells, Pancreatic endocrine cells, Distal tubular cells)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	146 NX
Lung	146 NX

Alveolar cells type 2	107 NX
Lung	107 NX

B-cells	139 NX
Kidney	254 NX
Colon	139 NX
Liver	74 NX

Basal glandular cells	57 NX
Prostate	57 NX

Basal keratinocytes	0 NX
Skin	0 NX

Bipolar cells	7 NX
Eye	6 NX

Cardiomyocytes	1 NX
Heart muscle	1 NX

Cholangiocytes	1004 NX
Liver	1004 NX

Ciliated cells	692 NX
Lung	692 NX

Club cells	181 NX
Lung	181 NX

Collecting duct cells	1235 NX
Kidney	1235 NX

Cone photoreceptor cells	2 NX
Eye	2 NX

Cytotrophoblasts	680 NX
Placenta	680 NX

Distal tubular cells	1348 NX
Kidney	1348 NX

Ductal cells	1087 NX
Pancreas	1087 NX

Early spermatids	21 NX
Testis	21 NX

Endothelial cells	2 NX
Placenta	271 NX
Prostate	45 NX
Lung	18 NX
Liver	9 NX
Pancreas	7 NX
Eye	2 NX
Testis	2 NX
Heart muscle	1 NX
Skin	0 NX

Enterocytes	820 NX
Rectum	1919 NX
Colon	1155 NX
Small intestine	7 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	3020 NX
Pancreas	3020 NX

Extravillous trophoblasts	709 NX
Placenta	709 NX

Fibroblasts	9 NX
Prostate	125 NX
Placenta	28 NX
Lung	9 NX
Heart muscle	2 NX
Skin	0 NX

Glandular cells	444 NX
Prostate	444 NX

Granulocytes	10 NX
Lung	12 NX
Colon	9 NX

Hepatocytes	4 NX
Liver	4 NX

Hofbauer cells	61 NX
Placenta	61 NX

Horizontal cells	0 NX
Eye	0 NX

Intestinal endocrine cells	553 NX
Colon	595 NX
Rectum	510 NX

Ito cells	53 NX
Liver	53 NX

Kupffer cells	9 NX
Liver	9 NX

Late spermatids	32 NX
Testis	32 NX

Leydig cells	10 NX
Testis	10 NX

Macrophages	12 NX
Kidney	35 NX
Pancreas	21 NX
Lung	18 NX
Prostate	11 NX
Testis	1 NX
Skin	0 NX

Melanocytes	0 NX
Skin	0 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	56 NX
Pancreas	56 NX

Mucus-secreting cells	392 NX
Colon	649 NX
Rectum	407 NX
Small intestine	41 NX

Muller glia cells	1 NX
Eye	1 NX

Pancreatic endocrine cells	1517 NX
Pancreas	1517 NX

Paneth cells	704 NX
Colon	1094 NX
Rectum	704 NX
Small intestine	530 NX

Peritubular cells	2 NX
Testis	2 NX

Proximal tubular cells	408 NX
Kidney	408 NX

Rod photoreceptor cells	1 NX
Eye	1 NX

Sertoli cells	7 NX
Testis	7 NX

Smooth muscle cells	0 NX
Prostate	38 NX
Pancreas	37 NX
Heart muscle	0 NX
Skin	0 NX

Spermatocytes	1 NX
Testis	1 NX

Spermatogonia	5 NX
Testis	5 NX

Suprabasal keratinocytes	0 NX
Skin	0 NX

Syncytiotrophoblasts	467 NX
Placenta	467 NX

T-cells	13 NX
Kidney	62 NX
Colon	61 NX
Lung	35 NX
Prostate	18 NX
Liver	3 NX
Skin	0 NX

Undifferentiated cells	735 NX
Colon	1071 NX
Rectum	1067 NX
Small intestine	127 NX

Urothelial cells	282 NX
Prostate	282 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.