Cell type atlas - CRIP1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

CRIP1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	CRIP1
Gene descriptionⁱ Full gene name according to HGNC.	Cysteine rich protein 1
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	3

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Ciliated cells, Alveolar cells type 1, Club cells)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (A549, CAPAN-2, HaCaT, HDLM-2, HeLa, OE19, T-47d)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Ciliated cells, Alveolar cells type 1, Club cells)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	911 NX
Lung	911 NX

Alveolar cells type 2	277 NX
Lung	277 NX

B-cells	126 NX
Colon	154 NX
Liver	130 NX
Kidney	62 NX

Basal glandular cells	1 NX
Prostate	1 NX

Basal keratinocytes	166 NX
Skin	166 NX

Bipolar cells	0 NX
Eye	0 NX

Cardiomyocytes	1 NX
Heart muscle	1 NX

Cholangiocytes	3 NX
Liver	3 NX

Ciliated cells	2667 NX
Lung	2667 NX

Club cells	875 NX
Lung	875 NX

Collecting duct cells	49 NX
Kidney	49 NX

Cone photoreceptor cells	0 NX
Eye	0 NX

Cytotrophoblasts	1 NX
Placenta	1 NX

Distal tubular cells	2 NX
Kidney	2 NX

Ductal cells	9 NX
Pancreas	9 NX

Early spermatids	3 NX
Testis	3 NX

Endothelial cells	11 NX
Lung	508 NX
Skin	143 NX
Pancreas	43 NX
Placenta	16 NX
Testis	11 NX
Liver	9 NX
Eye	4 NX
Prostate	3 NX
Heart muscle	1 NX

Enterocytes	494 NX
Small intestine	2035 NX
Rectum	280 NX
Colon	204 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	3 NX
Pancreas	3 NX

Extravillous trophoblasts	3 NX
Placenta	3 NX

Fibroblasts	16 NX
Lung	1556 NX
Skin	256 NX
Placenta	14 NX
Prostate	2 NX
Heart muscle	1 NX

Glandular cells	0 NX
Prostate	0 NX

Granulocytes	486 NX
Lung	863 NX
Colon	110 NX

Hepatocytes	1 NX
Liver	1 NX

Hofbauer cells	54 NX
Placenta	54 NX

Horizontal cells	0 NX
Eye	0 NX

Intestinal endocrine cells	74 NX
Rectum	103 NX
Colon	44 NX

Ito cells	27 NX
Liver	27 NX

Kupffer cells	189 NX
Liver	189 NX

Late spermatids	21 NX
Testis	21 NX

Leydig cells	23 NX
Testis	23 NX

Macrophages	297 NX
Lung	3074 NX
Skin	460 NX
Kidney	210 NX
Testis	140 NX
Prostate	16 NX
Pancreas	12 NX

Melanocytes	351 NX
Skin	351 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	698 NX
Pancreas	698 NX

Mucus-secreting cells	173 NX
Small intestine	377 NX
Rectum	183 NX
Colon	142 NX

Muller glia cells	0 NX
Eye	0 NX

Pancreatic endocrine cells	21 NX
Pancreas	21 NX

Paneth cells	407 NX
Small intestine	1101 NX
Rectum	407 NX
Colon	305 NX

Peritubular cells	9 NX
Testis	9 NX

Proximal tubular cells	2 NX
Kidney	2 NX

Rod photoreceptor cells	0 NX
Eye	0 NX

Sertoli cells	220 NX
Testis	220 NX

Smooth muscle cells	30 NX
Skin	314 NX
Prostate	30 NX
Pancreas	10 NX
Heart muscle	1 NX

Spermatocytes	0 NX
Testis	0 NX

Spermatogonia	10 NX
Testis	10 NX

Suprabasal keratinocytes	220 NX
Skin	220 NX

Syncytiotrophoblasts	1 NX
Placenta	1 NX

T-cells	240 NX
Lung	1330 NX
Skin	504 NX
Liver	282 NX
Kidney	223 NX
Colon	218 NX
Prostate	57 NX

Undifferentiated cells	157 NX
Rectum	226 NX
Small intestine	155 NX
Colon	123 NX

Urothelial cells	3 NX
Prostate	3 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.