Cell type atlas - MRPS18B - The Human Protein Atlas

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MRPS18B

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	MRPS18B
Gene descriptionⁱ Full gene name according to HGNC.	Mitochondrial ribosomal protein S18B
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	1

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in many
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	57 NX
Lung	57 NX

Alveolar cells type 2	44 NX
Lung	44 NX

B-cells	54 NX
Kidney	67 NX
Liver	58 NX
Colon	40 NX

Basal glandular cells	62 NX
Prostate	62 NX

Basal keratinocytes	33 NX
Skin	33 NX

Bipolar cells	43 NX
Eye	43 NX

Cardiomyocytes	136 NX
Heart muscle	136 NX

Cholangiocytes	102 NX
Liver	102 NX

Ciliated cells	54 NX
Lung	54 NX

Club cells	47 NX
Lung	47 NX

Collecting duct cells	45 NX
Kidney	45 NX

Cone photoreceptor cells	61 NX
Eye	61 NX

Cytotrophoblasts	107 NX
Placenta	107 NX

Distal tubular cells	164 NX
Kidney	164 NX

Ductal cells	89 NX
Pancreas	89 NX

Early spermatids	47 NX
Testis	47 NX

Endothelial cells	63 NX
Testis	76 NX
Placenta	72 NX
Pancreas	68 NX
Heart muscle	64 NX
Skin	64 NX
Liver	52 NX
Prostate	46 NX
Eye	44 NX
Lung	23 NX

Enterocytes	48 NX
Small intestine	73 NX
Rectum	37 NX
Colon	31 NX

Erythroid cells	23 NX
Liver	23 NX

Exocrine glandular cells	80 NX
Pancreas	80 NX

Extravillous trophoblasts	102 NX
Placenta	102 NX

Fibroblasts	52 NX
Placenta	66 NX
Heart muscle	57 NX
Skin	47 NX
Prostate	29 NX
Lung	28 NX

Glandular cells	46 NX
Prostate	46 NX

Granulocytes	37 NX
Colon	46 NX
Lung	28 NX

Hepatocytes	96 NX
Liver	96 NX

Hofbauer cells	72 NX
Placenta	72 NX

Horizontal cells	41 NX
Eye	41 NX

Intestinal endocrine cells	30 NX
Rectum	40 NX
Colon	20 NX

Ito cells	49 NX
Liver	49 NX

Kupffer cells	44 NX
Liver	44 NX

Late spermatids	27 NX
Testis	27 NX

Leydig cells	65 NX
Testis	65 NX

Macrophages	42 NX
Testis	66 NX
Kidney	53 NX
Pancreas	52 NX
Lung	50 NX
Prostate	33 NX
Skin	30 NX

Melanocytes	57 NX
Skin	57 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	94 NX
Pancreas	94 NX

Mucus-secreting cells	55 NX
Rectum	64 NX
Small intestine	51 NX
Colon	46 NX

Muller glia cells	39 NX
Eye	39 NX

Pancreatic endocrine cells	65 NX
Pancreas	65 NX

Paneth cells	60 NX
Rectum	69 NX
Small intestine	60 NX
Colon	9 NX

Peritubular cells	42 NX
Testis	42 NX

Proximal tubular cells	161 NX
Kidney	161 NX

Rod photoreceptor cells	51 NX
Eye	51 NX

Sertoli cells	52 NX
Testis	52 NX

Smooth muscle cells	67 NX
Pancreas	79 NX
Heart muscle	67 NX
Skin	60 NX
Prostate	37 NX

Spermatocytes	23 NX
Testis	23 NX

Spermatogonia	61 NX
Testis	61 NX

Suprabasal keratinocytes	39 NX
Skin	39 NX

Syncytiotrophoblasts	81 NX
Placenta	81 NX

T-cells	42 NX
Kidney	72 NX
Liver	53 NX
Colon	50 NX
Skin	42 NX
Lung	37 NX
Prostate	35 NX

Undifferentiated cells	80 NX
Small intestine	89 NX
Rectum	80 NX
Colon	63 NX

Urothelial cells	30 NX
Prostate	30 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.