MYO1C protein expression summary - The Human Protein Atlas

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MYO1C

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HUMAN PROTEIN ATLAS SUMMARYⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Proteinⁱ Full gene name according to HGNC.	Myosin IC
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	MYO1C (myr2)
Tissue specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on a combination of data from HPA, GTEX and FANTOM5. The categories include: tissue enriched, group enriched, tissue enhanced, low tissue specificity and not detected. Read more	Low tissue specificity
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed blood cell samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low immune cell specificity
Brain specificityⁱ The regional specificity category is based on mRNA expression levels in the analyzed brain samples, grouped into 10 main brain regions and calculated for the three different species. The human brain expression profile is based on a combination of data from GTEX and FANTOM5. The specificity categories include: regionally enriched, group enriched, regionally enhanced, low regional specificity and not detected. The classification rules are the same used for the tissue specificity category. Read more	Low human brain regional specificity
Cancer prognostic summary	Prognostic marker in lung cancer (unfavorable)
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Subcellular summaryⁱ The main location is characterized by presence in all tested cell lines and/or increased intensity compared to other locations. Additional locations are characterized by either a markedly lower staining intensity than the main location, or that it is only observed in a subset of the cell lines.	Located in Nuclear bodies, Plasma membrane
Protein function (UniProt)ⁱ Useful information about the protein provided by UniProt.	Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell's (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in stereocilia of vestibular hair cells. Binds phosphoinositides and links the actin cytoskeleton to cellular membranes.... show less
Molecular function (UniProt)ⁱ Keywords assigned by UniProt to proteins due to their particular molecular function.	Actin-binding, Calmodulin-binding, Motor protein, Myosin
Biological process (UniProt)ⁱ Keywords assigned by UniProt to proteins because they are involved in a particular biological process.	mRNA transport, Protein transport, Translocation, Transport
Ligand (UniProt)ⁱ Keywords assigned by UniProt to proteins because they bind, are associated with, or whose activity is dependent of some molecule.	ATP-binding, Nucleotide-binding
Gene summary (Entrez)ⁱ Useful information about the gene from Entrez	This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19. [provided by RefSeq, Jul 2008]... show less

TISSUE ATLASⁱ Summary of data presented in the Tissue Atlas and representative images of protein expression (left) and mRNA expression (right). The images are clickable and will redirect to more Tissue Atlas data. The Tissue Atlas contains information regarding the expression profiles of protein-coding genes in normal human tissue, both on the mRNA and protein level. The protein expression data is derived from antibody-based protein profiling using immunohistochemistry. Read more

Tissue specificity (RNA)ⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on a combination of data from HPA, GTEX and FANTOM5. The categories include: tissue enriched, group enriched, tissue enhanced, low tissue specificity and not detected. Read more	Low tissue specificity
Tissue distribution (RNA)ⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on a combination of data from HPA, GTEX and FANTOM5. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in many
Protein expressionⁱ A summary of the overall protein expression pattern across the analyzed normal tissues. The summary is based on knowledge-based annotation. "Estimation of protein expression could not be performed. View primary data." is shown for genes analyzed with a knowledge-based approach where available RNA-seq and gene/protein characterization data has been evaluated as not sufficient in combination with immunohistochemistry data to yield a reliable estimation of the protein expression profile. Read more	Cytoplasmic and membranous expression in most tissues.

SINGLE CELL TYPE ATLASⁱ Summary of data presented in the Cell Type Atlas and an interactive image showing mRNA expression in cell type groups e.g. epithelial cells and germ cells. The image is clickable and will redirect to more Cell Type Atlas data. The Cell Type Atlas contains information about single cell type RNA expression based on scRNAseq of human tissues. The data also covers transcriptomics analysis of human blood and cultured cell lines. Read more

Cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity

PATHOLOGY ATLASⁱ Summary of data presented in the Pathology Atlas , with representative images of protein expression in cancer (left) and correlation between mRNA expression and patient survival (right). Images are clickable and redirect to pages with more Pathology Atlas data. The Pathology Atlas contains mRNA and protein expression data from 17 different forms of human cancer, as well as correlation analysis of mRNA expression and patient survival. The protein expression data is derived from antibody-based protein profiling using immunohistochemistry. Read more
	Lung cancer p<0.001
Prognostic summary	Prognostic marker in lung cancer (unfavorable)
Cancer specificity (RNA)ⁱ Specificity of RNA expression in 17 cancer types is categorized as either cancer enriched, group enriched, cancer enhanced, low cancer specificity and not detected. Read more	Low cancer specificity
Cancer distribution (RNA)ⁱ Distribution of RNA expression in 17 cancer types is categorized as either detected in single, detected in some, detected in many, detected in all, or not detected. Read more	Detected in all

BRAIN ATLASⁱ Summary of data presented in the Brain Atlas and a representative image of mRNA expression in the human brain. The image is clickable and will redirect to more Brain Atlas data. The Brain Atlas explores the protein expression in the mammalian brain by visualization and integration of data from three mammalian species (human, pig and mouse). Transcriptomics data combined with affinity-based protein in situ localization down to single cell level is available in a brain-centric sub atlas of the Human Protein Atlas. Read more

Human regional specificityⁱ The regional specificity category is based on mRNA expression levels in the analyzed brain samples, grouped into 10 main brain regions and calculated for the three different species. The human brain expression profile is based on a combination of data from GTEX and FANTOM5. The specificity categories include: regionally enriched, group enriched, regionally enhanced, low regional specificity and not detected. The classification rules are the same used for the tissue specificity category. Read more	Low region specificity
Pig regional specificityⁱ The regional specificity category is based on mRNA expression levels in the analyzed brain samples, grouped into 10 main brain regions and calculated for the three different species. The human brain expression profile is based on a combination of data from GTEX and FANTOM5. The specificity categories include: regionally enriched, group enriched, regionally enhanced, low regional specificity and not detected. The classification rules are the same used for the tissue specificity category. Read more	Low region specificity
Mouse regional specificityⁱ The regional specificity category is based on mRNA expression levels in the analyzed brain samples, grouped into 10 main brain regions and calculated for the three different species. The human brain expression profile is based on a combination of data from GTEX and FANTOM5. The specificity categories include: regionally enriched, group enriched, regionally enhanced, low regional specificity and not detected. The classification rules are the same used for the tissue specificity category. Read more	Low region specificity

BLOOD ATLASⁱ Summary of data presented in the Blood Atlas and a representative image of mRNA expression in immune cells in the blood. The image is clickable and will redirect to more Blood Atlas data. The Blood Atlas contains single cell type RNA information covering various immune cells in the blood, e.g. B-cells and granulocytes. Analysis of the human secretome (including annotation of the genes predicted to be actively secreted to human blood) and proteins detected in human blood are also presented. Read more

Immune cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Detected in blood by immunoassayⁱ The blood-based immunoassay category applies to actively secreted proteins and is based on plasma or serum protein concentrations established with enzyme-linked immunosorbent assays, compiled from a literature search. The categories include: detected and not detected, where detection refers to a concentration found in the literature search. Read more	No (not applicable)
Detected in blood by mass spectrometryⁱ Detection or not of the gene in blood, based on spectral count estimations from a publicly available mass spectrometry-based plasma proteomics data set obtained from the PeptideAtlas.	Yes

CELL ATLASⁱ Summary of data presented in the Cell Atlas and a representative image of subcellular localization. The Cell Atlas provides RNA expression data derived from RNA sequencing of a large panel of cell lines and protein localization data derived from antibody-based profiling by immunofluorescence confocal microscopy, using a subset of cell lines selected based on RNA expression. Read more

Main locationⁱ Main subcellular location(s) and reliability score(s) for the encoded protein(s) in human cells. The main location(s) may be characterized by presence in all tested cell lines and/or ihigher staining intensity compared to the potential additional location(s). If available, links to overrepresentation analyses in Reactome, a free, open-source, curated and peer reviewed biological pathway database, are provided. An analysis is done for the corresponding gene set of the proteome localizing to the main and additional locations of the protein on this page, respectively. Read more	Localized to the Nuclear bodies, Plasma membrane
Cell cycle dependencyⁱ Cell-cycle dependance of single-cell varations in RNA and/or protein expression as observed in an additional assay for characterizing single-cell varations. "NA" indicates a lack of such data. Read more	NA

GENE INFORMATIONⁱ Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Gene name	MYO1C (HGNC Symbol)
Synonyms	myr2
Description	Myosin IC (HGNC Symbol)
Chromosome	17
Cytoband	p13.3
Chromosome location (bp)	1464186 - 1492812
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	10
Protein evidence	Evidence at protein level (all genes)
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Transporters
Ensembl	ENSG00000197879 (version 92.38)
Entrez gene	4641
UniProt	O00159 (UniProt - Evidence at protein level)
neXtProt	NX_O00159
Antibodypedia	MYO1C antibodies

PROTEIN BROWSERⁱ

MYO1C-201

MYO1C-202

MYO1C-203

MYO1C-204

MYO1C-205

MYO1C-206

MYO1C-211

MYO1C-216

MYO1C-217

MYO1C-220

PROTEIN INFORMATIONⁱ The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database. The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary for the selected splice variant. The data in the UniProt column can be expanded to show links to all matching UniProt identifiers for this protein. The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class. The Gene Ontology terms assigned to this protein are listed if expanding the Gene ontology column. The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius) and the number of predicted transmembrane region(s) (according to MDM) are also reported.
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MYO1C-201 ENSP00000352834 ENST00000359786	O00159 [Direct mapping] Unconventional myosin-Ic Show all	Transporters Transporter channels and pores Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Peptideatlas) Show all	GO:0000146 [microfilament motor activity] GO:0000166 [nucleotide binding] GO:0001726 [ruffle] GO:0003774 [motor activity] GO:0003777 [microtubule motor activity] GO:0003779 [actin binding] GO:0005102 [receptor binding] GO:0005515 [protein binding] GO:0005516 [calmodulin binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005643 [nuclear pore] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0005902 [microvillus] GO:0005903 [brush border] GO:0006605 [protein targeting] GO:0006612 [protein targeting to membrane] GO:0007018 [microtubule-based movement] GO:0008017 [microtubule binding] GO:0008022 [protein C-terminus binding] GO:0009925 [basal plasma membrane] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0016328 [lateral plasma membrane] GO:0016459 [myosin complex] GO:0016461 [unconventional myosin complex] GO:0016604 [nuclear body] GO:0017160 [Ral GTPase binding] GO:0030050 [vesicle transport along actin filament] GO:0030335 [positive regulation of cell migration] GO:0030659 [cytoplasmic vesicle membrane] GO:0030838 [positive regulation of actin filament polymerization] GO:0030898 [actin-dependent ATPase activity] GO:0031410 [cytoplasmic vesicle] GO:0031941 [filamentous actin] GO:0032420 [stereocilium] GO:0032421 [stereocilium bundle] GO:0032587 [ruffle membrane] GO:0038089 [positive regulation of cell migration by vascular endothelial growth factor signaling pathway] GO:0038096 [Fc-gamma receptor signaling pathway involved in phagocytosis] GO:0042995 [cell projection] GO:0045121 [membrane raft] GO:0045335 [phagocytic vesicle] GO:0045815 [positive regulation of gene expression, epigenetic] GO:0051015 [actin filament binding] GO:0051028 [mRNA transport] GO:0060171 [stereocilium membrane] GO:0070062 [extracellular exosome] GO:0071346 [cellular response to interferon-gamma] GO:0090314 [positive regulation of protein targeting to membrane] GO:1900078 [positive regulation of cellular response to insulin stimulus] GO:1900748 [positive regulation of vascular endothelial growth factor signaling pathway] GO:2000810 [regulation of bicellular tight junction assembly] Show all	1063 aa 121.7 kDa	No	0
MYO1C-202 ENSP00000354283 ENST00000361007	O00159 [Direct mapping] Unconventional myosin-Ic Show all	Transporters Transporter channels and pores Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Peptideatlas) Show all	GO:0000166 [nucleotide binding] GO:0001726 [ruffle] GO:0003774 [motor activity] GO:0003777 [microtubule motor activity] GO:0003779 [actin binding] GO:0005102 [receptor binding] GO:0005515 [protein binding] GO:0005516 [calmodulin binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005643 [nuclear pore] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0005902 [microvillus] GO:0006605 [protein targeting] GO:0006612 [protein targeting to membrane] GO:0007018 [microtubule-based movement] GO:0008017 [microtubule binding] GO:0009925 [basal plasma membrane] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0016328 [lateral plasma membrane] GO:0016459 [myosin complex] GO:0016461 [unconventional myosin complex] GO:0016604 [nuclear body] GO:0017160 [Ral GTPase binding] GO:0030335 [positive regulation of cell migration] GO:0031410 [cytoplasmic vesicle] GO:0031941 [filamentous actin] GO:0038089 [positive regulation of cell migration by vascular endothelial growth factor signaling pathway] GO:0038096 [Fc-gamma receptor signaling pathway involved in phagocytosis] GO:0042995 [cell projection] GO:0045121 [membrane raft] GO:0045815 [positive regulation of gene expression, epigenetic] GO:0051028 [mRNA transport] GO:0060171 [stereocilium membrane] GO:0070062 [extracellular exosome] GO:0090314 [positive regulation of protein targeting to membrane] GO:1900748 [positive regulation of vascular endothelial growth factor signaling pathway] GO:2000810 [regulation of bicellular tight junction assembly] Show all	1028 aa 117.9 kDa	No	0
MYO1C-203 ENSP00000412197 ENST00000438665	O00159 [Direct mapping] Unconventional myosin-Ic Show all	Transporters Transporter channels and pores Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Peptideatlas) Show all	GO:0000166 [nucleotide binding] GO:0001726 [ruffle] GO:0003774 [motor activity] GO:0003777 [microtubule motor activity] GO:0003779 [actin binding] GO:0005102 [receptor binding] GO:0005515 [protein binding] GO:0005516 [calmodulin binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005643 [nuclear pore] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0005902 [microvillus] GO:0006605 [protein targeting] GO:0006612 [protein targeting to membrane] GO:0007018 [microtubule-based movement] GO:0008017 [microtubule binding] GO:0009925 [basal plasma membrane] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0016328 [lateral plasma membrane] GO:0016459 [myosin complex] GO:0016461 [unconventional myosin complex] GO:0016604 [nuclear body] GO:0017160 [Ral GTPase binding] GO:0030335 [positive regulation of cell migration] GO:0031410 [cytoplasmic vesicle] GO:0031941 [filamentous actin] GO:0038089 [positive regulation of cell migration by vascular endothelial growth factor signaling pathway] GO:0038096 [Fc-gamma receptor signaling pathway involved in phagocytosis] GO:0042995 [cell projection] GO:0045121 [membrane raft] GO:0045815 [positive regulation of gene expression, epigenetic] GO:0051028 [mRNA transport] GO:0060171 [stereocilium membrane] GO:0070062 [extracellular exosome] GO:0090314 [positive regulation of protein targeting to membrane] GO:1900748 [positive regulation of vascular endothelial growth factor signaling pathway] GO:2000810 [regulation of bicellular tight junction assembly] Show all	1044 aa 119.6 kDa	No	0
MYO1C-204 ENSP00000437685 ENST00000545534	F5H6E2 [Direct mapping] Unconventional myosin-Ic Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Show all	GO:0000166 [nucleotide binding] GO:0003774 [motor activity] GO:0003777 [microtubule motor activity] GO:0003779 [actin binding] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005886 [plasma membrane] GO:0007018 [microtubule-based movement] GO:0008017 [microtubule binding] GO:0016459 [myosin complex] GO:0016604 [nuclear body] Show all	1039 aa 119 kDa	No	0
MYO1C-205 ENSP00000461682 ENST00000570490	I3L501 [Direct mapping] Unconventional myosin-Ic Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Show all	GO:0003774 [motor activity] GO:0003777 [microtubule motor activity] GO:0003779 [actin binding] GO:0005524 [ATP binding] GO:0007018 [microtubule-based movement] GO:0008017 [microtubule binding] GO:0016459 [myosin complex] Show all	168 aa 19 kDa	No	0
MYO1C-206 ENSP00000459271 ENST00000570984	I3L204 [Direct mapping] Unconventional myosin-Ic Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Show all	GO:0003774 [motor activity] GO:0003777 [microtubule motor activity] GO:0003779 [actin binding] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0007018 [microtubule-based movement] GO:0008017 [microtubule binding] GO:0016459 [myosin complex] Show all	1028 aa 117.9 kDa	No	0
MYO1C-211 ENSP00000460831 ENST00000573853	I3L3Y6 [Direct mapping] Unconventional myosin-Ic Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Show all	GO:0003774 [motor activity] GO:0003777 [microtubule motor activity] GO:0003779 [actin binding] GO:0005524 [ATP binding] GO:0007018 [microtubule-based movement] GO:0008017 [microtubule binding] GO:0016459 [myosin complex] Show all	170 aa 19.5 kDa	No	0
MYO1C-216 ENSP00000459174 ENST00000575158	O00159 [Direct mapping] Unconventional myosin-Ic Show all	Transporters Transporter channels and pores Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Peptideatlas) Show all	GO:0000166 [nucleotide binding] GO:0001726 [ruffle] GO:0003774 [motor activity] GO:0003777 [microtubule motor activity] GO:0003779 [actin binding] GO:0005102 [receptor binding] GO:0005515 [protein binding] GO:0005516 [calmodulin binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005643 [nuclear pore] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0005902 [microvillus] GO:0006605 [protein targeting] GO:0006612 [protein targeting to membrane] GO:0007018 [microtubule-based movement] GO:0008017 [microtubule binding] GO:0009925 [basal plasma membrane] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0016328 [lateral plasma membrane] GO:0016459 [myosin complex] GO:0016461 [unconventional myosin complex] GO:0016604 [nuclear body] GO:0017160 [Ral GTPase binding] GO:0030335 [positive regulation of cell migration] GO:0031410 [cytoplasmic vesicle] GO:0031941 [filamentous actin] GO:0038089 [positive regulation of cell migration by vascular endothelial growth factor signaling pathway] GO:0038096 [Fc-gamma receptor signaling pathway involved in phagocytosis] GO:0042995 [cell projection] GO:0045121 [membrane raft] GO:0045815 [positive regulation of gene expression, epigenetic] GO:0051028 [mRNA transport] GO:0060171 [stereocilium membrane] GO:0070062 [extracellular exosome] GO:0090314 [positive regulation of protein targeting to membrane] GO:1900748 [positive regulation of vascular endothelial growth factor signaling pathway] GO:2000810 [regulation of bicellular tight junction assembly] Show all	1028 aa 117.9 kDa	No	0
MYO1C-217 ENSP00000460415 ENST00000575335	I3L3F5 [Direct mapping] Unconventional myosin-Ic Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Show all	GO:0003774 [motor activity] GO:0003777 [microtubule motor activity] GO:0003779 [actin binding] GO:0005524 [ATP binding] GO:0007018 [microtubule-based movement] GO:0008017 [microtubule binding] GO:0016459 [myosin complex] Show all	137 aa 15.8 kDa	No	0
MYO1C-220 ENSP00000493973 ENST00000646049		Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Show all	GO:0003774 [motor activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0016459 [myosin complex] Show all	1028 aa 117.9 kDa	No	0

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