Cell type atlas - TOMM7 - The Human Protein Atlas

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TOMM7

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	TOMM7
Gene descriptionⁱ Full gene name according to HGNC.	Translocase of outer mitochondrial membrane 7
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular,Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	4

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	241 NX
Lung	241 NX

Alveolar cells type 2	278 NX
Lung	278 NX

B-cells	735 NX
Kidney	758 NX
Liver	748 NX
Colon	627 NX

Basal glandular cells	671 NX
Prostate	671 NX

Basal keratinocytes	787 NX
Skin	787 NX

Bipolar cells	247 NX
Eye	247 NX

Cardiomyocytes	1081 NX
Heart muscle	1081 NX

Cholangiocytes	685 NX
Liver	685 NX

Ciliated cells	305 NX
Lung	305 NX

Club cells	281 NX
Lung	281 NX

Collecting duct cells	332 NX
Kidney	332 NX

Cone photoreceptor cells	63 NX
Eye	63 NX

Cytotrophoblasts	408 NX
Placenta	408 NX

Distal tubular cells	1126 NX
Kidney	1126 NX

Ductal cells	384 NX
Pancreas	384 NX

Early spermatids	287 NX
Testis	287 NX

Endothelial cells	426 NX
Liver	883 NX
Testis	836 NX
Skin	761 NX
Prostate	548 NX
Placenta	426 NX
Eye	399 NX
Heart muscle	303 NX
Lung	265 NX
Pancreas	229 NX

Enterocytes	660 NX
Small intestine	875 NX
Colon	631 NX
Rectum	438 NX

Erythroid cells	420 NX
Liver	420 NX

Exocrine glandular cells	809 NX
Pancreas	809 NX

Extravillous trophoblasts	601 NX
Placenta	601 NX

Fibroblasts	501 NX
Skin	632 NX
Placenta	522 NX
Lung	447 NX
Prostate	435 NX
Heart muscle	360 NX

Glandular cells	702 NX
Prostate	702 NX

Granulocytes	488 NX
Lung	535 NX
Colon	441 NX

Hepatocytes	1059 NX
Liver	1059 NX

Hofbauer cells	606 NX
Placenta	606 NX

Horizontal cells	143 NX
Eye	143 NX

Intestinal endocrine cells	510 NX
Rectum	538 NX
Colon	483 NX

Ito cells	635 NX
Liver	635 NX

Kupffer cells	809 NX
Liver	809 NX

Late spermatids	298 NX
Testis	298 NX

Leydig cells	920 NX
Testis	920 NX

Macrophages	683 NX
Testis	885 NX
Kidney	800 NX
Skin	718 NX
Prostate	671 NX
Lung	385 NX
Pancreas	360 NX

Melanocytes	747 NX
Skin	747 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	556 NX
Pancreas	556 NX

Mucus-secreting cells	881 NX
Rectum	1008 NX
Colon	953 NX
Small intestine	774 NX

Muller glia cells	452 NX
Eye	452 NX

Pancreatic endocrine cells	538 NX
Pancreas	538 NX

Paneth cells	771 NX
Colon	786 NX
Rectum	771 NX
Small intestine	673 NX

Peritubular cells	714 NX
Testis	714 NX

Proximal tubular cells	838 NX
Kidney	838 NX

Rod photoreceptor cells	230 NX
Eye	230 NX

Sertoli cells	479 NX
Testis	479 NX

Smooth muscle cells	572 NX
Skin	699 NX
Prostate	572 NX
Heart muscle	485 NX
Pancreas	470 NX

Spermatocytes	455 NX
Testis	455 NX

Spermatogonia	181 NX
Testis	181 NX

Suprabasal keratinocytes	810 NX
Skin	810 NX

Syncytiotrophoblasts	340 NX
Placenta	340 NX

T-cells	683 NX
Skin	866 NX
Kidney	830 NX
Prostate	693 NX
Liver	622 NX
Colon	588 NX
Lung	401 NX

Undifferentiated cells	815 NX
Rectum	827 NX
Small intestine	795 NX
Colon	545 NX

Urothelial cells	663 NX
Prostate	663 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.