Cell type atlas - H1F0 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

H1F0

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	H1F0
Gene descriptionⁱ Full gene name according to HGNC.	H1 histone family member 0
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	1

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in many
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (OE19, U-2 OS)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	27 NX
Lung	27 NX

Alveolar cells type 2	115 NX
Lung	114 NX

B-cells	10 NX
Kidney	13 NX
Colon	7 NX
Liver	6 NX

Basal glandular cells	164 NX
Prostate	164 NX

Basal keratinocytes	62 NX
Skin	62 NX

Bipolar cells	30 NX
Eye	30 NX

Cardiomyocytes	40 NX
Heart muscle	40 NX

Cholangiocytes	107 NX
Liver	107 NX

Ciliated cells	98 NX
Lung	98 NX

Club cells	135 NX
Lung	135 NX

Collecting duct cells	98 NX
Kidney	98 NX

Cone photoreceptor cells	4 NX
Eye	4 NX

Cytotrophoblasts	33 NX
Placenta	33 NX

Distal tubular cells	106 NX
Kidney	106 NX

Ductal cells	132 NX
Pancreas	132 NX

Early spermatids	2 NX
Testis	2 NX

Endothelial cells	72 NX
Placenta	102 NX
Pancreas	97 NX
Lung	93 NX
Liver	72 NX
Heart muscle	64 NX
Skin	64 NX
Testis	53 NX
Prostate	37 NX
Eye	36 NX

Enterocytes	118 NX
Rectum	187 NX
Colon	118 NX
Small intestine	103 NX

Erythroid cells	280 NX
Liver	280 NX

Exocrine glandular cells	159 NX
Pancreas	159 NX

Extravillous trophoblasts	113 NX
Placenta	113 NX

Fibroblasts	83 NX
Placenta	88 NX
Skin	85 NX
Heart muscle	83 NX
Lung	40 NX
Prostate	36 NX

Glandular cells	175 NX
Prostate	175 NX

Granulocytes	22 NX
Lung	26 NX
Colon	18 NX

Hepatocytes	68 NX
Liver	68 NX

Hofbauer cells	60 NX
Placenta	59 NX

Horizontal cells	43 NX
Eye	43 NX

Intestinal endocrine cells	119 NX
Rectum	150 NX
Colon	88 NX

Ito cells	63 NX
Liver	63 NX

Kupffer cells	68 NX
Liver	68 NX

Late spermatids	4 NX
Testis	4 NX

Leydig cells	85 NX
Testis	85 NX

Macrophages	44 NX
Pancreas	77 NX
Testis	62 NX
Skin	51 NX
Prostate	50 NX
Lung	31 NX
Kidney	29 NX

Melanocytes	81 NX
Skin	81 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	93 NX
Pancreas	93 NX

Mucus-secreting cells	181 NX
Small intestine	217 NX
Rectum	193 NX
Colon	168 NX

Muller glia cells	46 NX
Eye	46 NX

Pancreatic endocrine cells	120 NX
Pancreas	120 NX

Paneth cells	160 NX
Colon	167 NX
Rectum	160 NX
Small intestine	147 NX

Peritubular cells	57 NX
Testis	57 NX

Proximal tubular cells	43 NX
Kidney	43 NX

Rod photoreceptor cells	6 NX
Eye	6 NX

Sertoli cells	110 NX
Testis	110 NX

Smooth muscle cells	97 NX
Heart muscle	133 NX
Skin	125 NX
Prostate	74 NX
Pancreas	45 NX

Spermatocytes	56 NX
Testis	56 NX

Spermatogonia	25 NX
Testis	25 NX

Suprabasal keratinocytes	78 NX
Skin	78 NX

Syncytiotrophoblasts	184 NX
Placenta	184 NX

T-cells	7 NX
Prostate	35 NX
Skin	15 NX
Lung	14 NX
Colon	7 NX
Kidney	6 NX
Liver	5 NX

Undifferentiated cells	103 NX
Rectum	136 NX
Small intestine	97 NX
Colon	70 NX

Urothelial cells	138 NX
Prostate	138 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.