Cell type atlas - RPS19BP1 - The Human Protein Atlas

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RPS19BP1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RPS19BP1
Gene descriptionⁱ Full gene name according to HGNC.	Ribosomal protein S19 binding protein 1
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	1

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	42 NX
Lung	42 NX

Alveolar cells type 2	44 NX
Lung	44 NX

B-cells	107 NX
Liver	162 NX
Kidney	120 NX
Colon	94 NX

Basal glandular cells	91 NX
Prostate	91 NX

Basal keratinocytes	122 NX
Skin	122 NX

Bipolar cells	96 NX
Eye	96 NX

Cardiomyocytes	68 NX
Heart muscle	68 NX

Cholangiocytes	110 NX
Liver	110 NX

Ciliated cells	35 NX
Lung	35 NX

Club cells	36 NX
Lung	36 NX

Collecting duct cells	93 NX
Kidney	93 NX

Cone photoreceptor cells	49 NX
Eye	49 NX

Cytotrophoblasts	134 NX
Placenta	134 NX

Distal tubular cells	184 NX
Kidney	184 NX

Ductal cells	167 NX
Pancreas	167 NX

Early spermatids	18 NX
Testis	18 NX

Endothelial cells	130 NX
Pancreas	211 NX
Liver	151 NX
Prostate	145 NX
Testis	143 NX
Placenta	130 NX
Skin	124 NX
Heart muscle	66 NX
Eye	62 NX
Lung	38 NX

Enterocytes	197 NX
Small intestine	219 NX
Colon	197 NX
Rectum	166 NX

Erythroid cells	47 NX
Liver	47 NX

Exocrine glandular cells	167 NX
Pancreas	167 NX

Extravillous trophoblasts	202 NX
Placenta	202 NX

Fibroblasts	95 NX
Skin	100 NX
Prostate	100 NX
Placenta	95 NX
Heart muscle	90 NX
Lung	27 NX

Glandular cells	166 NX
Prostate	166 NX

Granulocytes	69 NX
Colon	92 NX
Lung	47 NX

Hepatocytes	175 NX
Liver	175 NX

Hofbauer cells	186 NX
Placenta	186 NX

Horizontal cells	33 NX
Eye	33 NX

Intestinal endocrine cells	137 NX
Colon	143 NX
Rectum	131 NX

Ito cells	111 NX
Liver	111 NX

Kupffer cells	106 NX
Liver	106 NX

Late spermatids	22 NX
Testis	22 NX

Leydig cells	127 NX
Testis	127 NX

Macrophages	125 NX
Pancreas	253 NX
Skin	172 NX
Kidney	166 NX
Prostate	127 NX
Testis	98 NX
Lung	66 NX

Melanocytes	103 NX
Skin	103 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	172 NX
Pancreas	172 NX

Mucus-secreting cells	137 NX
Colon	280 NX
Small intestine	152 NX
Rectum	107 NX

Muller glia cells	81 NX
Eye	81 NX

Pancreatic endocrine cells	187 NX
Pancreas	187 NX

Paneth cells	165 NX
Colon	248 NX
Small intestine	165 NX
Rectum	133 NX

Peritubular cells	119 NX
Testis	119 NX

Proximal tubular cells	232 NX
Kidney	232 NX

Rod photoreceptor cells	82 NX
Eye	82 NX

Sertoli cells	78 NX
Testis	78 NX

Smooth muscle cells	104 NX
Pancreas	201 NX
Prostate	110 NX
Skin	103 NX
Heart muscle	63 NX

Spermatocytes	59 NX
Testis	59 NX

Spermatogonia	146 NX
Testis	146 NX

Suprabasal keratinocytes	129 NX
Skin	129 NX

Syncytiotrophoblasts	110 NX
Placenta	110 NX

T-cells	136 NX
Colon	142 NX
Prostate	140 NX
Kidney	136 NX
Liver	127 NX
Skin	122 NX
Lung	52 NX

Undifferentiated cells	131 NX
Colon	196 NX
Small intestine	131 NX
Rectum	116 NX

Urothelial cells	113 NX
Prostate	113 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.