Cell type atlas - RPS27L - The Human Protein Atlas

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RPS27L

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RPS27L
Gene descriptionⁱ Full gene name according to HGNC.	Ribosomal protein S27 like
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	6

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Proximal tubular cells)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Proximal tubular cells)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	89 NX
Lung	89 NX

Alveolar cells type 2	200 NX
Lung	200 NX

B-cells	257 NX
Liver	628 NX
Kidney	263 NX
Colon	149 NX

Basal glandular cells	227 NX
Prostate	227 NX

Basal keratinocytes	227 NX
Skin	227 NX

Bipolar cells	32 NX
Eye	32 NX

Cardiomyocytes	319 NX
Heart muscle	319 NX

Cholangiocytes	599 NX
Liver	599 NX

Ciliated cells	234 NX
Lung	234 NX

Club cells	154 NX
Lung	154 NX

Collecting duct cells	389 NX
Kidney	389 NX

Cone photoreceptor cells	45 NX
Eye	45 NX

Cytotrophoblasts	244 NX
Placenta	244 NX

Distal tubular cells	766 NX
Kidney	766 NX

Ductal cells	755 NX
Pancreas	755 NX

Early spermatids	36 NX
Testis	36 NX

Endothelial cells	230 NX
Pancreas	358 NX
Liver	335 NX
Skin	311 NX
Placenta	296 NX
Prostate	230 NX
Testis	209 NX
Heart muscle	178 NX
Eye	166 NX
Lung	140 NX

Enterocytes	819 NX
Small intestine	1273 NX
Colon	607 NX
Rectum	563 NX

Erythroid cells	234 NX
Liver	234 NX

Exocrine glandular cells	679 NX
Pancreas	679 NX

Extravillous trophoblasts	1142 NX
Placenta	1142 NX

Fibroblasts	251 NX
Skin	376 NX
Prostate	251 NX
Heart muscle	247 NX
Placenta	217 NX
Lung	163 NX

Glandular cells	333 NX
Prostate	333 NX

Granulocytes	293 NX
Lung	328 NX
Colon	257 NX

Hepatocytes	900 NX
Liver	900 NX

Hofbauer cells	483 NX
Placenta	483 NX

Horizontal cells	13 NX
Eye	13 NX

Intestinal endocrine cells	274 NX
Rectum	283 NX
Colon	265 NX

Ito cells	301 NX
Liver	301 NX

Kupffer cells	377 NX
Liver	377 NX

Late spermatids	22 NX
Testis	22 NX

Leydig cells	291 NX
Testis	291 NX

Macrophages	318 NX
Kidney	574 NX
Pancreas	517 NX
Prostate	344 NX
Skin	281 NX
Lung	233 NX
Testis	177 NX

Melanocytes	442 NX
Skin	442 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	1587 NX
Pancreas	1587 NX

Mucus-secreting cells	625 NX
Colon	739 NX
Small intestine	625 NX
Rectum	571 NX

Muller glia cells	110 NX
Eye	110 NX

Pancreatic endocrine cells	1031 NX
Pancreas	1030 NX

Paneth cells	692 NX
Colon	700 NX
Rectum	692 NX
Small intestine	628 NX

Peritubular cells	280 NX
Testis	280 NX

Proximal tubular cells	1955 NX
Kidney	1955 NX

Rod photoreceptor cells	68 NX
Eye	68 NX

Sertoli cells	259 NX
Testis	259 NX

Smooth muscle cells	357 NX
Pancreas	980 NX
Heart muscle	380 NX
Prostate	347 NX
Skin	336 NX

Spermatocytes	143 NX
Testis	143 NX

Spermatogonia	82 NX
Testis	82 NX

Suprabasal keratinocytes	216 NX
Skin	216 NX

Syncytiotrophoblasts	197 NX
Placenta	197 NX

T-cells	234 NX
Kidney	382 NX
Prostate	314 NX
Colon	234 NX
Skin	217 NX
Liver	214 NX
Lung	204 NX

Undifferentiated cells	639 NX
Small intestine	710 NX
Colon	585 NX
Rectum	561 NX

Urothelial cells	176 NX
Prostate	176 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.