Cell type atlas - CHD9 - The Human Protein Atlas

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CHD9

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	CHD9
Gene descriptionⁱ Full gene name according to HGNC.	Chromodomain helicase DNA binding protein 9
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Enzymes Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	10

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Rod photoreceptor cells, Cone photoreceptor cells)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (plasmacytoid DC)
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Rod photoreceptor cells, Cone photoreceptor cells)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	66 NX
Lung	66 NX

Alveolar cells type 2	57 NX
Lung	57 NX

B-cells	64 NX
Kidney	125 NX
Colon	94 NX
Liver	31 NX

Basal glandular cells	104 NX
Prostate	104 NX

Basal keratinocytes	51 NX
Skin	51 NX

Bipolar cells	251 NX
Eye	251 NX

Cardiomyocytes	34 NX
Heart muscle	34 NX

Cholangiocytes	43 NX
Liver	43 NX

Ciliated cells	68 NX
Lung	68 NX

Club cells	67 NX
Lung	67 NX

Collecting duct cells	86 NX
Kidney	86 NX

Cone photoreceptor cells	473 NX
Eye	473 NX

Cytotrophoblasts	15 NX
Placenta	15 NX

Distal tubular cells	40 NX
Kidney	40 NX

Ductal cells	50 NX
Pancreas	50 NX

Early spermatids	12 NX
Testis	12 NX

Endothelial cells	77 NX
Liver	128 NX
Eye	104 NX
Testis	94 NX
Skin	90 NX
Prostate	77 NX
Heart muscle	73 NX
Lung	70 NX
Placenta	58 NX
Pancreas	39 NX

Enterocytes	67 NX
Colon	71 NX
Small intestine	65 NX
Rectum	65 NX

Erythroid cells	47 NX
Liver	47 NX

Exocrine glandular cells	32 NX
Pancreas	32 NX

Extravillous trophoblasts	24 NX
Placenta	24 NX

Fibroblasts	77 NX
Prostate	88 NX
Heart muscle	87 NX
Placenta	78 NX
Skin	77 NX
Lung	65 NX

Glandular cells	86 NX
Prostate	86 NX

Granulocytes	92 NX
Lung	137 NX
Colon	46 NX

Hepatocytes	61 NX
Liver	61 NX

Hofbauer cells	62 NX
Placenta	62 NX

Horizontal cells	208 NX
Eye	208 NX

Intestinal endocrine cells	84 NX
Rectum	94 NX
Colon	75 NX

Ito cells	88 NX
Liver	88 NX

Kupffer cells	59 NX
Liver	59 NX

Late spermatids	15 NX
Testis	15 NX

Leydig cells	100 NX
Testis	100 NX

Macrophages	68 NX
Lung	83 NX
Testis	80 NX
Prostate	77 NX
Kidney	67 NX
Skin	55 NX
Pancreas	49 NX

Melanocytes	64 NX
Skin	64 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	75 NX
Pancreas	75 NX

Mucus-secreting cells	67 NX
Small intestine	102 NX
Colon	88 NX
Rectum	60 NX

Muller glia cells	159 NX
Eye	159 NX

Pancreatic endocrine cells	30 NX
Pancreas	30 NX

Paneth cells	60 NX
Small intestine	161 NX
Colon	60 NX
Rectum	54 NX

Peritubular cells	116 NX
Testis	116 NX

Proximal tubular cells	48 NX
Kidney	48 NX

Rod photoreceptor cells	752 NX
Eye	752 NX

Sertoli cells	58 NX
Testis	58 NX

Smooth muscle cells	73 NX
Heart muscle	104 NX
Prostate	80 NX
Skin	67 NX
Pancreas	55 NX

Spermatocytes	80 NX
Testis	80 NX

Spermatogonia	36 NX
Testis	36 NX

Suprabasal keratinocytes	66 NX
Skin	66 NX

Syncytiotrophoblasts	21 NX
Placenta	21 NX

T-cells	49 NX
Liver	59 NX
Kidney	57 NX
Lung	49 NX
Prostate	48 NX
Colon	41 NX
Skin	35 NX

Undifferentiated cells	70 NX
Small intestine	71 NX
Colon	71 NX
Rectum	45 NX

Urothelial cells	73 NX
Prostate	73 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.