Cell type atlas - CTDNEP1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

CTDNEP1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	CTDNEP1
Gene descriptionⁱ Full gene name according to HGNC.	CTD nuclear envelope phosphatase 1
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Enzymes
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular,Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	8

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	24 NX
Lung	24 NX

Alveolar cells type 2	21 NX
Lung	21 NX

B-cells	49 NX
Liver	60 NX
Colon	55 NX
Kidney	36 NX

Basal glandular cells	41 NX
Prostate	41 NX

Basal keratinocytes	42 NX
Skin	42 NX

Bipolar cells	43 NX
Eye	43 NX

Cardiomyocytes	11 NX
Heart muscle	11 NX

Cholangiocytes	31 NX
Liver	31 NX

Ciliated cells	9 NX
Lung	9 NX

Club cells	25 NX
Lung	25 NX

Collecting duct cells	38 NX
Kidney	38 NX

Cone photoreceptor cells	22 NX
Eye	22 NX

Cytotrophoblasts	54 NX
Placenta	54 NX

Distal tubular cells	10 NX
Kidney	10 NX

Ductal cells	54 NX
Pancreas	54 NX

Early spermatids	4 NX
Testis	4 NX

Endothelial cells	44 NX
Liver	83 NX
Pancreas	68 NX
Prostate	56 NX
Placenta	50 NX
Testis	45 NX
Eye	43 NX
Skin	43 NX
Heart muscle	11 NX
Lung	3 NX

Enterocytes	63 NX
Rectum	83 NX
Colon	65 NX
Small intestine	56 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	74 NX
Pancreas	74 NX

Extravillous trophoblasts	98 NX
Placenta	98 NX

Fibroblasts	42 NX
Placenta	48 NX
Skin	45 NX
Prostate	31 NX
Heart muscle	14 NX
Lung	9 NX

Glandular cells	51 NX
Prostate	51 NX

Granulocytes	20 NX
Lung	21 NX
Colon	18 NX

Hepatocytes	34 NX
Liver	34 NX

Hofbauer cells	81 NX
Placenta	81 NX

Horizontal cells	29 NX
Eye	29 NX

Intestinal endocrine cells	71 NX
Colon	71 NX
Rectum	70 NX

Ito cells	41 NX
Liver	41 NX

Kupffer cells	83 NX
Liver	83 NX

Late spermatids	5 NX
Testis	5 NX

Leydig cells	54 NX
Testis	54 NX

Macrophages	53 NX
Prostate	96 NX
Testis	75 NX
Pancreas	75 NX
Skin	51 NX
Kidney	49 NX
Lung	28 NX

Melanocytes	27 NX
Skin	27 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	37 NX
Pancreas	37 NX

Mucus-secreting cells	74 NX
Rectum	78 NX
Small intestine	76 NX
Colon	60 NX

Muller glia cells	46 NX
Eye	46 NX

Pancreatic endocrine cells	68 NX
Pancreas	68 NX

Paneth cells	46 NX
Rectum	63 NX
Colon	46 NX
Small intestine	32 NX

Peritubular cells	44 NX
Testis	44 NX

Proximal tubular cells	29 NX
Kidney	29 NX

Rod photoreceptor cells	28 NX
Eye	28 NX

Sertoli cells	26 NX
Testis	26 NX

Smooth muscle cells	33 NX
Pancreas	68 NX
Prostate	33 NX
Skin	26 NX
Heart muscle	5 NX

Spermatocytes	15 NX
Testis	15 NX

Spermatogonia	36 NX
Testis	36 NX

Suprabasal keratinocytes	59 NX
Skin	59 NX

Syncytiotrophoblasts	70 NX
Placenta	70 NX

T-cells	36 NX
Colon	47 NX
Liver	38 NX
Kidney	38 NX
Skin	35 NX
Lung	12 NX
Prostate	4 NX

Undifferentiated cells	59 NX
Rectum	63 NX
Small intestine	57 NX
Colon	55 NX

Urothelial cells	56 NX
Prostate	56 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.