Cell type atlas - MRPL52 - The Human Protein Atlas

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MRPL52

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	MRPL52
Gene descriptionⁱ Full gene name according to HGNC.	Mitochondrial ribosomal protein L52
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	11

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	69 NX
Lung	69 NX

Alveolar cells type 2	79 NX
Lung	79 NX

B-cells	124 NX
Liver	225 NX
Kidney	143 NX
Colon	106 NX

Basal glandular cells	65 NX
Prostate	65 NX

Basal keratinocytes	108 NX
Skin	108 NX

Bipolar cells	21 NX
Eye	21 NX

Cardiomyocytes	96 NX
Heart muscle	96 NX

Cholangiocytes	201 NX
Liver	201 NX

Ciliated cells	95 NX
Lung	95 NX

Club cells	90 NX
Lung	90 NX

Collecting duct cells	129 NX
Kidney	129 NX

Cone photoreceptor cells	18 NX
Eye	18 NX

Cytotrophoblasts	163 NX
Placenta	163 NX

Distal tubular cells	235 NX
Kidney	235 NX

Ductal cells	222 NX
Pancreas	222 NX

Early spermatids	48 NX
Testis	48 NX

Endothelial cells	84 NX
Pancreas	247 NX
Placenta	179 NX
Skin	116 NX
Liver	94 NX
Testis	84 NX
Lung	67 NX
Prostate	64 NX
Eye	55 NX
Heart muscle	34 NX

Enterocytes	247 NX
Colon	252 NX
Small intestine	249 NX
Rectum	128 NX

Erythroid cells	94 NX
Liver	94 NX

Exocrine glandular cells	273 NX
Pancreas	273 NX

Extravillous trophoblasts	247 NX
Placenta	247 NX

Fibroblasts	73 NX
Placenta	112 NX
Skin	71 NX
Lung	62 NX
Prostate	41 NX
Heart muscle	35 NX

Glandular cells	87 NX
Prostate	87 NX

Granulocytes	121 NX
Colon	147 NX
Lung	95 NX

Hepatocytes	226 NX
Liver	226 NX

Hofbauer cells	209 NX
Placenta	209 NX

Horizontal cells	19 NX
Eye	19 NX

Intestinal endocrine cells	133 NX
Rectum	143 NX
Colon	122 NX

Ito cells	106 NX
Liver	106 NX

Kupffer cells	152 NX
Liver	152 NX

Late spermatids	45 NX
Testis	44 NX

Leydig cells	52 NX
Testis	52 NX

Macrophages	104 NX
Pancreas	278 NX
Kidney	260 NX
Skin	119 NX
Testis	94 NX
Lung	92 NX
Prostate	58 NX

Melanocytes	118 NX
Skin	118 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	248 NX
Pancreas	248 NX

Mucus-secreting cells	189 NX
Colon	350 NX
Small intestine	195 NX
Rectum	157 NX

Muller glia cells	50 NX
Eye	50 NX

Pancreatic endocrine cells	304 NX
Pancreas	304 NX

Paneth cells	207 NX
Colon	216 NX
Small intestine	207 NX
Rectum	162 NX

Peritubular cells	46 NX
Testis	46 NX

Proximal tubular cells	361 NX
Kidney	361 NX

Rod photoreceptor cells	28 NX
Eye	28 NX

Sertoli cells	65 NX
Testis	65 NX

Smooth muscle cells	85 NX
Pancreas	334 NX
Skin	86 NX
Prostate	55 NX
Heart muscle	54 NX

Spermatocytes	125 NX
Testis	125 NX

Spermatogonia	106 NX
Testis	106 NX

Suprabasal keratinocytes	130 NX
Skin	130 NX

Syncytiotrophoblasts	105 NX
Placenta	105 NX

T-cells	86 NX
Kidney	126 NX
Skin	116 NX
Colon	86 NX
Liver	82 NX
Lung	81 NX
Prostate	48 NX

Undifferentiated cells	184 NX
Colon	243 NX
Small intestine	184 NX
Rectum	164 NX

Urothelial cells	88 NX
Prostate	88 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.