Expression of RPS21 in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 1020.34
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

914.7

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	4350.9
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	3724.9
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	2828.0
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	2471.7
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	2315.1
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	2182.3
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	2124.5
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	1850.3
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	1779.7
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	1770.9
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	1768.4
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	1764.1
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	1748.3
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	1734.1
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	1609.7
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	1553.3
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	1539.6
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	1522.6
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	1467.7
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	1464.1
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	1451.2
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	1446.5
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	1374.0
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	1359.6
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	1344.9
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	1343.1
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	1336.3
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	1329.4
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	1307.8
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	1269.3
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	1268.7
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	1235.3
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	1207.2
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	1199.3
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	1174.4
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	1125.4
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	1124.9
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	1112.8
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	1056.8
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	1027.3
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	1020.7
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	1019.9
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	1017.5
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	998.5
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	997.4
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	974.5
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	961.3
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	951.4
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	943.4
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	938.3
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	933.2
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	933.1
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	927.6
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	927.6
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	925.3
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	925.3
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	922.4
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	920.2
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	919.5
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	919.2
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	909.5
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	905.6
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	899.6
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	899.2
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	894.8
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	882.9
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	880.2
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	877.5
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	874.7
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	874.7
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	864.8
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	857.6
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	839.2
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	838.2
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	836.5
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	817.1
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	815.0
TCGA-CL-4957-01A	79 years, female, dead, 425 days	813.9
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	812.1
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	810.9
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	804.1
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	801.0
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	789.6
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	786.9
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	786.9
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	785.4
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	775.8
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	751.1
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	749.3
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	737.7
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	736.1
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	731.2
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	727.1
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	713.7
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	704.3
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	701.3
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	690.4
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	685.5
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	678.6
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	674.6
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	674.6
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	672.4
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	669.2
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	668.7
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	650.4
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	649.4
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	648.6
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	640.1
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	630.7
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	628.4
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	608.8
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	600.0
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	591.9
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	589.1
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	571.7
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	568.0
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	541.9
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	539.1
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	532.7
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	531.3
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	523.7
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	522.4
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	521.6
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	509.4
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	506.3
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	494.7
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	493.8
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	482.3
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	481.9
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	479.9
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	476.8
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	476.3
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	471.4
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	466.5
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	463.0
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	453.7
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	447.6
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	429.0
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	420.8
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	419.0
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	418.0
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	414.1
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	405.7
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	401.8
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	400.9
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	362.3
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	354.9
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	351.1
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	346.4
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	329.1
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	327.1
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	311.7
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	304.3
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	258.9
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	233.6
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	227.9
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	179.7
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	172.7
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	142.9
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