Cell type atlas - B3GNT2 - The Human Protein Atlas

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B3GNT2

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	B3GNT2
Gene descriptionⁱ Full gene name according to HGNC.	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Enzymes Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (REH)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	60 NX
Lung	60 NX

Alveolar cells type 2	10 NX
Lung	10 NX

B-cells	25 NX
Colon	34 NX
Kidney	22 NX
Liver	19 NX

Basal glandular cells	27 NX
Prostate	27 NX

Basal keratinocytes	63 NX
Skin	63 NX

Bipolar cells	16 NX
Eye	16 NX

Cardiomyocytes	9 NX
Heart muscle	9 NX

Cholangiocytes	18 NX
Liver	18 NX

Ciliated cells	5 NX
Lung	5 NX

Club cells	3 NX
Lung	3 NX

Collecting duct cells	17 NX
Kidney	17 NX

Cone photoreceptor cells	0 NX
Eye	0 NX

Cytotrophoblasts	31 NX
Placenta	31 NX

Distal tubular cells	20 NX
Kidney	20 NX

Ductal cells	21 NX
Pancreas	21 NX

Early spermatids	0 NX
Testis	0 NX

Endothelial cells	21 NX
Skin	54 NX
Eye	41 NX
Prostate	30 NX
Heart muscle	24 NX
Liver	18 NX
Placenta	17 NX
Testis	13 NX
Pancreas	11 NX
Lung	3 NX

Enterocytes	17 NX
Rectum	45 NX
Colon	31 NX
Small intestine	12 NX

Erythroid cells	47 NX
Liver	47 NX

Exocrine glandular cells	51 NX
Pancreas	51 NX

Extravillous trophoblasts	30 NX
Placenta	30 NX

Fibroblasts	35 NX
Skin	42 NX
Placenta	38 NX
Prostate	13 NX
Lung	11 NX
Heart muscle	3 NX

Glandular cells	24 NX
Prostate	24 NX

Granulocytes	4 NX
Lung	7 NX
Colon	0 NX

Hepatocytes	16 NX
Liver	16 NX

Hofbauer cells	52 NX
Placenta	52 NX

Horizontal cells	0 NX
Eye	0 NX

Intestinal endocrine cells	9 NX
Colon	14 NX
Rectum	5 NX

Ito cells	37 NX
Liver	37 NX

Kupffer cells	23 NX
Liver	23 NX

Late spermatids	0 NX
Testis	0 NX

Leydig cells	2 NX
Testis	2 NX

Macrophages	20 NX
Pancreas	40 NX
Skin	36 NX
Prostate	35 NX
Lung	17 NX
Kidney	17 NX
Testis	11 NX

Melanocytes	34 NX
Skin	34 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	24 NX
Pancreas	24 NX

Mucus-secreting cells	19 NX
Rectum	23 NX
Colon	18 NX
Small intestine	18 NX

Muller glia cells	8 NX
Eye	8 NX

Pancreatic endocrine cells	38 NX
Pancreas	38 NX

Paneth cells	22 NX
Colon	37 NX
Rectum	22 NX
Small intestine	7 NX

Peritubular cells	2 NX
Testis	2 NX

Proximal tubular cells	19 NX
Kidney	19 NX

Rod photoreceptor cells	2 NX
Eye	2 NX

Sertoli cells	65 NX
Testis	65 NX

Smooth muscle cells	52 NX
Skin	123 NX
Prostate	52 NX
Heart muscle	41 NX
Pancreas	20 NX

Spermatocytes	0 NX
Testis	0 NX

Spermatogonia	2 NX
Testis	2 NX

Suprabasal keratinocytes	57 NX
Skin	57 NX

Syncytiotrophoblasts	55 NX
Placenta	55 NX

T-cells	18 NX
Skin	54 NX
Colon	47 NX
Prostate	31 NX
Kidney	22 NX
Liver	11 NX
Lung	2 NX

Undifferentiated cells	12 NX
Rectum	14 NX
Colon	13 NX
Small intestine	8 NX

Urothelial cells	35 NX
Prostate	35 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.