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CTNNB1
HUMAN PROTEIN ATLAS SUMMARYi
Proteini Catenin beta 1
Gene namei CTNNB1 (armadillo, beta-catenin, CTNNB)
Tissue specificityi
Low tissue specificity
Single cell type specificityi
Cell type enhanced (Syncytiotrophoblasts)
Blood specificityi
Low immune cell specificity
Brain specificityi
Low human brain regional specificity
Cancer prognostic
summary
Prognostic marker in colorectal cancer (favorable)
Predicted locationi
Intracellular
Subcellular summaryi
Located in Plasma membrane
Protein function (UniProt)i Key downstream component of the canonical Wnt signaling pathway 1, 2, 3, 4, 5, 6, 7, 8. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome 9, 10, 11, 12, 13, 14, 15, 16. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes 17, 18, 19, 20, 21, 22, 23, 24. Involved in the regulation of cell adhesion, as component of an E-cadherin:catenin adhesion complex (By similarity). Acts as a negative regulator of centrosome cohesion 25. Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization 26. Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2 27. Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML 28. Promotes neurogenesis by maintaining sympathetic neuroblasts within the cell cycle (By similarity). Involved in chondrocyte differentiation via interaction with SOX9: SOX9-binding competes with the binding sites of TCF/LEF within CTNNB1, thereby inhibiting the Wnt signaling (By similarity). show less
Molecular function (UniProt)i Activator
Biological process (UniProt)i Cell adhesion, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation, Wnt signaling pathway
Disease involvementi Cancer-related genes, Disease mutation, Mental retardation
Gene summary (Entrez)i The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016] show less
TISSUE ATLASi
Tissue specificity (RNA)i Low tissue specificity
Tissue distribution (RNA)i Detected in all
Protein expressioni Membranous expression in most tissues.
SINGLE CELL TYPE ATLASi
Cell type specificityi Cell type enhanced (Syncytiotrophoblasts)
Cell line specificityi Low cell line specificity
PATHOLOGY ATLASi
Colorectal cancer p<0.001
Prognostic summary Prognostic marker in colorectal cancer (favorable)
Cancer specificity (RNA)i Low cancer specificity
Cancer distribution (RNA)i Detected in all
BRAIN ATLASi
Human regional specificityi Low region specificity
Pig regional specificityi Low region specificity
Mouse regional specificityi Low region specificity
BLOOD ATLASi
Immune cell specificityi Low cell type specificity
Detected in blood by
immunoassayi		 No (not applicable)
Detected in blood by
mass spectrometryi		 Yes
CELL ATLASi
Main locationi Localized to the Plasma membrane
Cell cycle dependencyi NA
GENE INFORMATIONi
Gene name CTNNB1 (HGNC Symbol)
Synonyms armadillo, beta-catenin, CTNNB
Description Catenin beta 1 (HGNC Symbol)
Chromosome 3
Cytoband p22.1
Chromosome location (bp) 41194741 - 41260096
Number of transcriptsi 43
Protein evidence Evidence at protein level (all genes)
Protein classi Cancer-related genes
Disease related genes
Plasma proteins
Ensembl ENSG00000168036 (version 92.38)
Entrez gene 1499
UniProt P35222 (UniProt - Evidence at protein level)
neXtProt NX_P35222
Antibodypedia CTNNB1 antibodies
PROTEIN BROWSERi
«
CTNNB1-201
CTNNB1-202
CTNNB1-203
CTNNB1-204
CTNNB1-205
CTNNB1-206
CTNNB1-207
CTNNB1-208
CTNNB1-209
CTNNB1-210
CTNNB1-216
CTNNB1-217
CTNNB1-218
CTNNB1-219
CTNNB1-220
CTNNB1-221
CTNNB1-222
CTNNB1-223
CTNNB1-225
CTNNB1-226
CTNNB1-228
CTNNB1-229
CTNNB1-230
CTNNB1-233
CTNNB1-234
CTNNB1-235
CTNNB1-236
CTNNB1-237
CTNNB1-238
CTNNB1-239
CTNNB1-241
CTNNB1-242
CTNNB1-244
CTNNB1-245
CTNNB1-246
CTNNB1-248
CTNNB1-249
CTNNB1-250
CTNNB1-251
CTNNB1-252
CTNNB1-254
CTNNB1-255
CTNNB1-256
»
PROTEIN INFORMATIONi
Splice variant UniProt Protein class Gene ontology Length & mass Signal peptide
(predicted)		 Transmembrane regions
(predicted)
CTNNB1-201
ENSP00000344456
ENST00000349496
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-202
ENSP00000379486
ENST00000396183
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-203
ENSP00000379488
ENST00000396185
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-204
ENSP00000385604
ENST00000405570
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-205
ENSP00000400508
ENST00000426215
C9IZ65 [Direct mapping]
Catenin beta-1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Show all
 59 aa
6.5 kDa 		No 0
CTNNB1-206
ENSP00000412219
ENST00000431914
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
E7EMJ5 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007165 [signal transduction]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-207
ENSP00000387455
ENST00000433400
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
C9JV16 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-208
ENSP00000401599
ENST00000441708
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
E9PDF9 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-209
ENSP00000409302
ENST00000450969
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
E7EV28 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-210
ENSP00000411226
ENST00000453024
B4DGU4 [Direct mapping]
Catenin beta-1; cDNA FLJ57878, highly similar to Beta-catenin
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Show all
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0007165 [signal transduction]
GO:0034333 [adherens junction assembly]
Show all
 774 aa
84.8 kDa 		No 0
CTNNB1-216
ENSP00000495244
ENST00000642248
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-217
ENSP00000495076
ENST00000642315
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-218
ENSP00000495719
ENST00000642426
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-219
ENSP00000496295
ENST00000642836
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Show all
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0034333 [adherens junction assembly]
Show all
 774 aa
84.8 kDa 		No 0
CTNNB1-220
ENSP00000496020
ENST00000642886
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Show all
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0034333 [adherens junction assembly]
Show all
 744 aa
81.4 kDa 		No 0
CTNNB1-221
ENSP00000494422
ENST00000642986
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Show all
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0034333 [adherens junction assembly]
Show all
 737 aa
80.7 kDa 		No 0
CTNNB1-222
ENSP00000496385
ENST00000642992
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-223
ENSP00000495450
ENST00000643031
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-225
ENSP00000494677
ENST00000643297
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-226
ENSP00000494411
ENST00000643541
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-228
ENSP00000494053
ENST00000643977
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-229
ENSP00000493610
ENST00000643992
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-230
ENSP00000496649
ENST00000644138
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Show all
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0034333 [adherens junction assembly]
Show all
 702 aa
77.2 kDa 		No 0
CTNNB1-233
ENSP00000494780
ENST00000644524
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Show all
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0034333 [adherens junction assembly]
Show all
 774 aa
84.8 kDa 		No 0
CTNNB1-234
ENSP00000495794
ENST00000644678
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Show all
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0034333 [adherens junction assembly]
Show all
 774 aa
84.8 kDa 		No 0
CTNNB1-235
ENSP00000495992
ENST00000644867
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-236
ENSP00000496511
ENST00000644873
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Show all
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0034333 [adherens junction assembly]
Show all
 780 aa
85.4 kDa 		No 0
CTNNB1-237
ENSP00000496584
ENST00000644906
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Show all
GO:0005488 [binding]
GO:0005515 [protein binding]
Show all
 186 aa
20.4 kDa 		No 0
CTNNB1-238
ENSP00000496180
ENST00000645210
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-239
ENSP00000494654
ENST00000645276
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Show all
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0034333 [adherens junction assembly]
Show all
 783 aa
85.7 kDa 		No 0
CTNNB1-241
ENSP00000495360
ENST00000645320
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000578 [embryonic axis specification]
GO:0000904 [cell morphogenesis involved in differentiation]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001501 [skeletal system development]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001570 [vasculogenesis]
GO:0001658 [branching involved in ureteric bud morphogenesis]
GO:0001701 [in utero embryonic development]
GO:0001702 [gastrulation with mouth forming second]
GO:0001706 [endoderm formation]
GO:0001708 [cell fate specification]
GO:0001709 [cell fate determination]
GO:0001711 [endodermal cell fate commitment]
GO:0001764 [neuron migration]
GO:0001822 [kidney development]
GO:0001837 [epithelial to mesenchymal transition]
GO:0001840 [neural plate development]
GO:0001944 [vasculature development]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0002053 [positive regulation of mesenchymal cell proliferation]
GO:0002089 [lens morphogenesis in camera-type eye]
GO:0003266 [regulation of secondary heart field cardioblast proliferation]
GO:0003338 [metanephros morphogenesis]
GO:0003340 [negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis]
GO:0003682 [chromatin binding]
GO:0003700 [DNA binding transcription factor activity]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005916 [fascia adherens]
GO:0005923 [bicellular tight junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007160 [cell-matrix adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007268 [chemical synaptic transmission]
GO:0007398 [ectoderm development]
GO:0007399 [nervous system development]
GO:0007403 [glial cell fate determination]
GO:0007507 [heart development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008283 [cell proliferation]
GO:0008284 [positive regulation of cell proliferation]
GO:0008285 [negative regulation of cell proliferation]
GO:0009948 [anterior/posterior axis specification]
GO:0009950 [dorsal/ventral axis specification]
GO:0009953 [dorsal/ventral pattern formation]
GO:0009954 [proximal/distal pattern formation]
GO:0009987 [cellular process]
GO:0010468 [regulation of gene expression]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0014704 [intercalated disc]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016331 [morphogenesis of embryonic epithelium]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0016600 [flotillin complex]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019901 [protein kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0021819 [layer formation in cerebral cortex]
GO:0022009 [central nervous system vasculogenesis]
GO:0022405 [hair cycle process]
GO:0030018 [Z disc]
GO:0030027 [lamellipodium]
GO:0030054 [cell junction]
GO:0030097 [hemopoiesis]
GO:0030154 [cell differentiation]
GO:0030182 [neuron differentiation]
GO:0030217 [T cell differentiation]
GO:0030316 [osteoclast differentiation]
GO:0030324 [lung development]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030539 [male genitalia development]
GO:0030856 [regulation of epithelial cell differentiation]
GO:0030858 [positive regulation of epithelial cell differentiation]
GO:0030877 [beta-catenin destruction complex]
GO:0030900 [forebrain development]
GO:0030901 [midbrain development]
GO:0030902 [hindbrain development]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0031016 [pancreas development]
GO:0031069 [hair follicle morphogenesis]
GO:0031253 [cell projection membrane]
GO:0031528 [microvillus membrane]
GO:0031641 [regulation of myelination]
GO:0032212 [positive regulation of telomere maintenance via telomerase]
GO:0032331 [negative regulation of chondrocyte differentiation]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033077 [T cell differentiation in thymus]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034332 [adherens junction organization]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0034613 [cellular protein localization]
GO:0034750 [Scrib-APC-beta-catenin complex]
GO:0035050 [embryonic heart tube development]
GO:0035112 [genitalia morphogenesis]
GO:0035115 [embryonic forelimb morphogenesis]
GO:0035116 [embryonic hindlimb morphogenesis]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042127 [regulation of cell proliferation]
GO:0042129 [regulation of T cell proliferation]
GO:0042475 [odontogenesis of dentin-containing tooth]
GO:0042493 [response to drug]
GO:0042733 [embryonic digit morphogenesis]
GO:0042981 [regulation of apoptotic process]
GO:0043065 [positive regulation of apoptotic process]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043296 [apical junction complex]
GO:0043410 [positive regulation of MAPK cascade]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0043588 [skin development]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0044798 [nuclear transcription factor complex]
GO:0045177 [apical part of cell]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045453 [bone resorption]
GO:0045595 [regulation of cell differentiation]
GO:0045596 [negative regulation of cell differentiation]
GO:0045603 [positive regulation of endothelial cell differentiation]
GO:0045667 [regulation of osteoblast differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045670 [regulation of osteoclast differentiation]
GO:0045671 [negative regulation of osteoclast differentiation]
GO:0045743 [positive regulation of fibroblast growth factor receptor signaling pathway]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0046982 [protein heterodimerization activity]
GO:0048096 [chromatin-mediated maintenance of transcription]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048469 [cell maturation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048489 [synaptic vesicle transport]
GO:0048513 [animal organ development]
GO:0048538 [thymus development]
GO:0048599 [oocyte development]
GO:0048617 [embryonic foregut morphogenesis]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0048715 [negative regulation of oligodendrocyte differentiation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0050808 [synapse organization]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0051884 [regulation of timing of anagen]
GO:0051973 [positive regulation of telomerase activity]
GO:0060066 [oviduct development]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060173 [limb development]
GO:0060439 [trachea morphogenesis]
GO:0060440 [trachea formation]
GO:0060441 [epithelial tube branching involved in lung morphogenesis]
GO:0060479 [lung cell differentiation]
GO:0060484 [lung-associated mesenchyme development]
GO:0060492 [lung induction]
GO:0060548 [negative regulation of cell death]
GO:0060742 [epithelial cell differentiation involved in prostate gland development]
GO:0060769 [positive regulation of epithelial cell proliferation involved in prostate gland development]
GO:0060789 [hair follicle placode formation]
GO:0060916 [mesenchymal cell proliferation involved in lung development]
GO:0061047 [positive regulation of branching involved in lung morphogenesis]
GO:0061154 [endothelial tube morphogenesis]
GO:0061198 [fungiform papilla formation]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0061550 [cranial ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070491 [repressing transcription factor binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072001 [renal system development]
GO:0072033 [renal vesicle formation]
GO:0072053 [renal inner medulla development]
GO:0072054 [renal outer medulla development]
GO:0072079 [nephron tubule formation]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0097718 [disordered domain specific binding]
GO:0098609 [cell-cell adhesion]
GO:1901215 [negative regulation of neuron death]
GO:1903204 [negative regulation of oxidative stress-induced neuron death]
GO:1904501 [positive regulation of chromatin-mediated maintenance of transcription]
GO:1904793 [regulation of euchromatin binding]
GO:1904796 [regulation of core promoter binding]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904888 [cranial skeletal system development]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990403 [embryonic brain development]
GO:1990791 [dorsal root ganglion development]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000017 [positive regulation of determination of dorsal identity]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
GO:2001234 [negative regulation of apoptotic signaling pathway]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-242
ENSP00000494467
ENST00000645493
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Show all
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0034333 [adherens junction assembly]
Show all
 774 aa
84.8 kDa 		No 0
CTNNB1-244
ENSP00000495286
ENST00000645900
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Show all
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0034333 [adherens junction assembly]
Show all
 774 aa
84.8 kDa 		No 0
CTNNB1-245
ENSP00000495287
ENST00000645927
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Show all
GO:0005488 [binding]
GO:0005515 [protein binding]
Show all
 367 aa
40.1 kDa 		No 0
CTNNB1-246
ENSP00000494845
ENST00000645982
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-248
ENSP00000495426
ENST00000646116
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Show all
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0034333 [adherens junction assembly]
Show all
 774 aa
84.8 kDa 		No 0
CTNNB1-249
ENSP00000495161
ENST00000646174
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Show all
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0034333 [adherens junction assembly]
Show all
 774 aa
84.8 kDa 		No 0
CTNNB1-250
ENSP00000494914
ENST00000646369
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-251
ENSP00000496067
ENST00000646381
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Show all
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0034333 [adherens junction assembly]
Show all
 774 aa
84.8 kDa 		No 0
CTNNB1-252
ENSP00000496021
ENST00000646725
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-254
ENSP00000494849
ENST00000647264
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Show all
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0034333 [adherens junction assembly]
Show all
 752 aa
82.4 kDa 		No 0
CTNNB1-255
ENSP00000493533
ENST00000647390
P35222 [Target identity:100%; Query identity:100%]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Peptideatlas)
Show all
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005719 [nuclear euchromatin]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [macromolecular complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035411 [catenin import into nucleus]
GO:0035635 [entry of bacterium into host cell]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0043065 [positive regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-256
ENSP00000493583
ENST00000647413
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Show all
GO:0004871 [signal transducer activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0034333 [adherens junction assembly]
Show all
 779 aa
85.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.