Cell type atlas - NDUFV1 - The Human Protein Atlas

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NDUFV1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	NDUFV1
Gene descriptionⁱ Full gene name according to HGNC.	NADH:ubiquinone oxidoreductase core subunit V1
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Disease related genes Enzymes Potential drug targets
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	11

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	57 NX
Lung	57 NX

Alveolar cells type 2	81 NX
Lung	81 NX

B-cells	64 NX
Liver	101 NX
Kidney	58 NX
Colon	45 NX

Basal glandular cells	71 NX
Prostate	71 NX

Basal keratinocytes	71 NX
Skin	71 NX

Bipolar cells	67 NX
Eye	67 NX

Cardiomyocytes	409 NX
Heart muscle	409 NX

Cholangiocytes	66 NX
Liver	66 NX

Ciliated cells	72 NX
Lung	72 NX

Club cells	67 NX
Lung	67 NX

Collecting duct cells	82 NX
Kidney	82 NX

Cone photoreceptor cells	47 NX
Eye	47 NX

Cytotrophoblasts	181 NX
Placenta	181 NX

Distal tubular cells	337 NX
Kidney	337 NX

Ductal cells	97 NX
Pancreas	97 NX

Early spermatids	57 NX
Testis	57 NX

Endothelial cells	54 NX
Heart muscle	81 NX
Skin	76 NX
Placenta	60 NX
Pancreas	54 NX
Eye	53 NX
Prostate	43 NX
Testis	41 NX
Lung	35 NX
Liver	34 NX

Enterocytes	205 NX
Colon	296 NX
Small intestine	158 NX
Rectum	135 NX

Erythroid cells	23 NX
Liver	23 NX

Exocrine glandular cells	98 NX
Pancreas	98 NX

Extravillous trophoblasts	128 NX
Placenta	128 NX

Fibroblasts	80 NX
Heart muscle	173 NX
Placenta	101 NX
Skin	74 NX
Prostate	44 NX
Lung	43 NX

Glandular cells	48 NX
Prostate	48 NX

Granulocytes	59 NX
Lung	72 NX
Colon	46 NX

Hepatocytes	122 NX
Liver	122 NX

Hofbauer cells	122 NX
Placenta	122 NX

Horizontal cells	60 NX
Eye	60 NX

Intestinal endocrine cells	95 NX
Rectum	115 NX
Colon	75 NX

Ito cells	53 NX
Liver	53 NX

Kupffer cells	67 NX
Liver	67 NX

Late spermatids	159 NX
Testis	159 NX

Leydig cells	61 NX
Testis	61 NX

Macrophages	68 NX
Kidney	98 NX
Pancreas	82 NX
Skin	71 NX
Prostate	61 NX
Testis	59 NX
Lung	50 NX

Melanocytes	108 NX
Skin	108 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	84 NX
Pancreas	84 NX

Mucus-secreting cells	142 NX
Colon	169 NX
Rectum	149 NX
Small intestine	94 NX

Muller glia cells	63 NX
Eye	63 NX

Pancreatic endocrine cells	68 NX
Pancreas	68 NX

Paneth cells	127 NX
Rectum	141 NX
Colon	127 NX
Small intestine	63 NX

Peritubular cells	56 NX
Testis	56 NX

Proximal tubular cells	399 NX
Kidney	399 NX

Rod photoreceptor cells	60 NX
Eye	60 NX

Sertoli cells	45 NX
Testis	45 NX

Smooth muscle cells	99 NX
Skin	103 NX
Pancreas	99 NX
Heart muscle	99 NX
Prostate	82 NX

Spermatocytes	77 NX
Testis	77 NX

Spermatogonia	78 NX
Testis	78 NX

Suprabasal keratinocytes	70 NX
Skin	70 NX

Syncytiotrophoblasts	158 NX
Placenta	158 NX

T-cells	71 NX
Kidney	101 NX
Liver	96 NX
Lung	71 NX
Colon	71 NX
Prostate	65 NX
Skin	55 NX

Undifferentiated cells	225 NX
Colon	297 NX
Rectum	225 NX
Small intestine	180 NX

Urothelial cells	79 NX
Prostate	79 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.