Cell type atlas - CD320 - The Human Protein Atlas

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CD320

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	CD320
Gene descriptionⁱ Full gene name according to HGNC.	CD320 molecule
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	CD markers Disease related genes
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Spermatocytes)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in many
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (NB-4, RPMI-8226)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Spermatocytes)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	12 NX
Lung	12 NX

Alveolar cells type 2	20 NX
Lung	20 NX

B-cells	29 NX
Liver	79 NX
Kidney	31 NX
Colon	27 NX

Basal glandular cells	25 NX
Prostate	25 NX

Basal keratinocytes	17 NX
Skin	17 NX

Bipolar cells	51 NX
Eye	51 NX

Cardiomyocytes	27 NX
Heart muscle	27 NX

Cholangiocytes	10 NX
Liver	10 NX

Ciliated cells	12 NX
Lung	12 NX

Club cells	10 NX
Lung	10 NX

Collecting duct cells	17 NX
Kidney	17 NX

Cone photoreceptor cells	31 NX
Eye	31 NX

Cytotrophoblasts	33 NX
Placenta	33 NX

Distal tubular cells	12 NX
Kidney	12 NX

Ductal cells	46 NX
Pancreas	46 NX

Early spermatids	21 NX
Testis	21 NX

Endothelial cells	86 NX
Testis	204 NX
Placenta	173 NX
Skin	128 NX
Pancreas	107 NX
Heart muscle	95 NX
Prostate	85 NX
Eye	82 NX
Liver	72 NX
Lung	47 NX

Enterocytes	13 NX
Colon	139 NX
Rectum	32 NX
Small intestine	3 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	16 NX
Pancreas	16 NX

Extravillous trophoblasts	40 NX
Placenta	40 NX

Fibroblasts	27 NX
Skin	38 NX
Placenta	26 NX
Prostate	23 NX
Heart muscle	20 NX
Lung	15 NX

Glandular cells	49 NX
Prostate	49 NX

Granulocytes	12 NX
Colon	18 NX
Lung	5 NX

Hepatocytes	17 NX
Liver	17 NX

Hofbauer cells	24 NX
Placenta	24 NX

Horizontal cells	21 NX
Eye	21 NX

Intestinal endocrine cells	49 NX
Colon	51 NX
Rectum	47 NX

Ito cells	51 NX
Liver	51 NX

Kupffer cells	4 NX
Liver	4 NX

Late spermatids	42 NX
Testis	42 NX

Leydig cells	20 NX
Testis	20 NX

Macrophages	6 NX
Skin	13 NX
Kidney	11 NX
Testis	6 NX
Lung	5 NX
Prostate	4 NX
Pancreas	2 NX

Melanocytes	37 NX
Skin	37 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	6 NX
Pancreas	6 NX

Mucus-secreting cells	32 NX
Colon	122 NX
Rectum	44 NX
Small intestine	8 NX

Muller glia cells	18 NX
Eye	18 NX

Pancreatic endocrine cells	23 NX
Pancreas	23 NX

Paneth cells	66 NX
Rectum	73 NX
Colon	66 NX
Small intestine	7 NX

Peritubular cells	16 NX
Testis	16 NX

Proximal tubular cells	39 NX
Kidney	39 NX

Rod photoreceptor cells	38 NX
Eye	38 NX

Sertoli cells	13 NX
Testis	13 NX

Smooth muscle cells	31 NX
Skin	40 NX
Pancreas	31 NX
Heart muscle	25 NX
Prostate	24 NX

Spermatocytes	120 NX
Testis	120 NX

Spermatogonia	28 NX
Testis	28 NX

Suprabasal keratinocytes	12 NX
Skin	12 NX

Syncytiotrophoblasts	30 NX
Placenta	30 NX

T-cells	36 NX
Kidney	82 NX
Skin	44 NX
Liver	39 NX
Lung	35 NX
Colon	33 NX
Prostate	13 NX

Undifferentiated cells	89 NX
Colon	228 NX
Rectum	89 NX
Small intestine	23 NX

Urothelial cells	19 NX
Prostate	19 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.