Expression of B2M in pancreatic cancer - The Human Protein Atlas

PANCREATIC CANCER - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

B2M is not prognostic in pancreatic cancer

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 626.03
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

851.5

Number of samples

176

Samples

Sample	Description	FPKM
TCGA-IB-7646-01A	60 years, male, white, stage:iib, dead, 145 days	2178.3
TCGA-HZ-8637-01A	76 years, female, white, stage:iib, dead, 517 days	2020.4
TCGA-F2-A7TX-01A	77 years, male, white, stage:iib, dead, 95 days	1898.0
TCGA-FB-AAQ3-01A	65 years, female, white, stage:iib, dead, 31 days	1878.2
TCGA-F2-6879-01A	57 years, male, white, stage:iib, dead, 334 days	1712.7
TCGA-IB-7651-01A	64 years, female, white, stage:iib, dead, 603 days	1682.7
TCGA-HZ-8638-01A	84 years, female, white, stage:ia, dead, 151 days	1650.6
TCGA-2J-AAB4-01A	48 years, male, white, stage:iib, alive, 729 days	1648.7
TCGA-HV-A7OL-01A	70 years, male, asian, stage:iia, alive, 252 days	1606.8
TCGA-Z5-AAPL-01A	74 years, female, white, stage:iia, alive, 467 days	1582.8
TCGA-HZ-7919-01A	52 years, female, white, stage:iib, dead, 593 days	1581.6
TCGA-IB-AAUO-01A	64 years, female, white, stage:iib, dead, 239 days	1474.6
TCGA-3A-A9IH-01A	66 years, female, white, stage:ia, alive, 1021 days	1440.6
TCGA-IB-AAUN-01A	74 years, female, white, stage:ib, dead, 144 days	1390.1
TCGA-HZ-7918-01A	72 years, male, white, stage:iib, alive, 969 days	1378.0
TCGA-IB-A5SP-01A	77 years, male, white, stage:iia, alive, 482 days	1348.0
TCGA-HV-AA8X-01A	75 years, female, asian, stage:iib, dead, 532 days	1321.0
TCGA-HZ-A4BH-01A	75 years, male, white, stage:iib, alive, 194 days	1294.6
TCGA-OE-A75W-01A	75 years, male, white, stage:iia, dead, 267 days	1254.8
TCGA-2J-AAB8-01A	71 years, male, white, stage:iib, alive, 80 days	1249.4
TCGA-FB-A4P5-01A	69 years, female, white, stage:iib, dead, 179 days	1238.8
TCGA-PZ-A5RE-01A	44 years, female, white, stage:iib, dead, 470 days	1237.1
TCGA-3E-AAAY-01A	67 years, male, white, stage:iib, alive, 2285 days	1230.1
TCGA-IB-AAUS-01A	84 years, female, white, stage:iib, alive, 225 days	1215.6
TCGA-HZ-A77Q-01A	55 years, female, white, stage:iib, alive, 33 days	1214.4
TCGA-YY-A8LH-01A	61 years, female, white, stage:iib, alive, 2016 days	1192.2
TCGA-HV-A5A5-01A	61 years, female, asian, stage:iib, alive, 289 days	1175.9
TCGA-US-A77E-01A	73 years, male, white, stage:iib, dead, 430 days	1172.5
TCGA-IB-7645-01A	44 years, female, stage:iib, dead, 1502 days	1164.3
TCGA-HZ-8315-01A	54 years, female, white, stage:iia, dead, 299 days	1139.1
TCGA-HZ-7920-01A	71 years, male, white, stage:ib, dead, 236 days	1123.2
TCGA-Q3-A5QY-01A	58 years, male, white, stage:iib, alive, 416 days	1119.1
TCGA-HZ-7923-01A	65 years, male, white, stage:iia, alive, 314 days	1091.2
TCGA-IB-AAUU-01A	35 years, male, white, stage:iib, alive, 245 days	1090.4
TCGA-HZ-7925-01A	66 years, male, white, stage:iib, dead, 614 days	1075.3
TCGA-IB-7889-01A	86 years, female, white, stage:iib, dead, 481 days	1074.0
TCGA-IB-7886-01A	80 years, male, white, stage:iib, dead, 123 days	1038.4
TCGA-IB-7888-01A	66 years, female, black or african american, stage:iia, dead, 1332 days	1032.4
TCGA-IB-7649-01A	73 years, female, stage:iib, dead, 467 days	1026.6
TCGA-IB-8127-01A	59 years, male, white, stage:iib, alive, 522 days	1022.9
TCGA-HZ-A4BK-01A	72 years, male, white, stage:iib, alive, 657 days	1021.3
TCGA-IB-7885-01A	78 years, female, white, stage:iib, alive, 1257 days	1011.0
TCGA-IB-7891-01A	49 years, female, white, stage:iib, dead, 913 days	1010.2
TCGA-2J-AAB1-01A	65 years, male, white, stage:iib, dead, 66 days	1002.5
TCGA-FB-AAQ6-01A	85 years, male, white, stage:ia, dead, 244 days	998.0
TCGA-RL-AAAS-01A	60 years, female, white, stage:ib, alive, 9 days	988.0
TCGA-IB-AAUP-01A	68 years, male, white, stage:iib, alive, 431 days	980.8
TCGA-IB-A5SS-01A	64 years, female, white, stage:iib, dead, 460 days	966.9
TCGA-US-A77G-01A	64 years, male, white, stage:iib, dead, 12 days	959.9
TCGA-IB-7887-01A	62 years, female, white, stage:iib, dead, 110 days	958.6
TCGA-HZ-8001-01A	69 years, male, white, stage:iii, alive, 706 days	958.5
TCGA-M8-A5N4-01A	48 years, female, stage:iia, alive, 584 days	954.3
TCGA-3A-A9J0-01A	75 years, male, white, stage:iib, alive, 743 days	947.6
TCGA-US-A774-01A	76 years, female, white, stage:iib, dead, 695 days	937.0
TCGA-IB-7652-01A	49 years, female, asian, stage:iib, alive, 1116 days	930.1
TCGA-F2-A8YN-01A	76 years, male, white, stage:iia, alive, 517 days	926.9
TCGA-2J-AABF-01A	73 years, male, white, stage:iib, dead, 691 days	925.8
TCGA-IB-A5SO-01A	71 years, male, white, stage:iib, dead, 365 days	924.5
TCGA-HZ-A49I-01A	77 years, male, white, stage:iib, dead, 308 days	923.6
TCGA-2J-AABP-01A	58 years, female, white, stage:iib, alive, 463 days	913.5
TCGA-S4-A8RP-01A	77 years, female, white, stage:iib, dead, 702 days	910.2
TCGA-HZ-A49H-01A	68 years, female, white, stage:iib, alive, 491 days	908.4
TCGA-XN-A8T5-01A	53 years, female, white, stage:ib, alive, 720 days	906.9
TCGA-HZ-7922-01A	61 years, female, white, stage:iib, alive, 4 days	899.6
TCGA-F2-A44G-01A	79 years, female, white, stage:iib, dead, 233 days	897.0
TCGA-IB-AAUQ-01A	50 years, male, white, stage:iib, dead, 183 days	896.3
TCGA-2J-AABU-01A	56 years, male, white, stage:iib, dead, 277 days	895.9
TCGA-H8-A6C1-01A	53 years, male, white, stage:iia, alive, 671 days	895.1
TCGA-IB-A5ST-01A	64 years, female, white, stage:iib, alive, 635 days	888.3
TCGA-IB-AAUT-01A	65 years, male, white, stage:iib, alive, 287 days	887.7
TCGA-FB-AAPQ-01A	65 years, male, white, stage:iib, dead, 1130 days	883.0
TCGA-2L-AAQJ-01A	49 years, female, white, stage:iii, dead, 394 days	866.4
TCGA-HZ-8636-01A	58 years, female, white, stage:iv, dead, 545 days	860.9
TCGA-2J-AABO-01A	43 years, male, white, stage:iib, alive, 440 days	857.0
TCGA-S4-A8RO-01A	75 years, female, white, stage:iib, alive, 525 days	854.5
TCGA-3A-A9IB-01A	69 years, female, white, stage:iib, dead, 224 days	841.9
TCGA-HV-A5A4-01A	72 years, female, asian, stage:iia, alive, 232 days	841.9
TCGA-FB-AAPS-01A	62 years, female, white, stage:iib, alive, 228 days	841.6
TCGA-HZ-A49G-01A	58 years, female, white, stage:iib, alive, 660 days	839.7
TCGA-2J-AAB6-01A	75 years, male, white, stage:iia, dead, 293 days	839.6
TCGA-YH-A8SY-01A	73 years, female, white, alive, 388 days	836.9
TCGA-IB-7897-01A	54 years, female, white, stage:iib, dead, 486 days	835.9
TCGA-IB-AAUR-01A	67 years, male, white, stage:iib, alive, 338 days	834.9
TCGA-US-A77J-01A	81 years, female, white, stage:iib, dead, 568 days	834.3
TCGA-2L-AAQL-01A	82 years, male, white, stage:iib, dead, 292 days	826.8
TCGA-HZ-8519-01A	73 years, male, white, stage:ia, alive, 454 days	823.5
TCGA-2J-AABR-01A	60 years, female, white, stage:iia, alive, 438 days	823.4
TCGA-FB-AAPY-01A	71 years, male, white, stage:iib, dead, 1059 days	821.4
TCGA-3A-A9I7-01A	45 years, male, black or african american, stage:iib, alive, 1323 days	818.3
TCGA-XD-AAUL-01A	56 years, male, white, stage:iia, alive, 498 days	809.4
TCGA-US-A776-01A	61 years, male, white, stage:iia, alive, 1216 days	806.5
TCGA-F2-7273-01A	54 years, male, black or african american, stage:iib, dead, 592 days	803.5
TCGA-IB-7654-01A	80 years, male, white, stage:iib, dead, 476 days	802.9
TCGA-FB-A4P6-01A	54 years, male, white, stage:iib, alive, 767 days	798.4
TCGA-FB-AAQ0-01A	68 years, male, white, stage:iia, dead, 473 days	798.3
TCGA-YB-A89D-01A	59 years, male, white, stage:iib, alive, 350 days	793.2
TCGA-HZ-A77O-01A	77 years, female, white, stage:iib, dead, 160 days	792.1
TCGA-IB-7893-01A	64 years, male, white, stage:iia, dead, 117 days	790.0
TCGA-2L-AAQI-01A	66 years, male, white, stage:iib, dead, 103 days	787.4
TCGA-F2-7276-01A	64 years, male, white, stage:iib, dead, 216 days	787.0
TCGA-HZ-8002-01A	61 years, male, white, stage:iib, dead, 366 days	786.9
TCGA-RB-AA9M-01A	43 years, male, white, stage:iib, alive, 286 days	783.4
TCGA-IB-AAUW-01A	63 years, female, white, stage:iib, dead, 230 days	762.6
TCGA-3A-A9IU-01A	65 years, male, white, stage:iib, dead, 458 days	762.0
TCGA-HZ-7924-01A	60 years, female, white, stage:iia, alive, 840 days	759.9
TCGA-FB-A7DR-01A	48 years, male, asian, stage:iia, dead, 353 days	758.8
TCGA-3A-A9IC-01A	61 years, female, white, stage:iib, dead, 738 days	754.9
TCGA-FB-A5VM-01A	74 years, male, white, stage:ib, dead, 498 days	741.6
TCGA-LB-A7SX-01A	74 years, female, black or african american, stage:iib, dead, 393 days	732.5
TCGA-Q3-AA2A-01A	64 years, female, white, stage:ib, alive, 95 days	729.0
TCGA-IB-A5SQ-01A	56 years, female, white, stage:ib, dead, 219 days	715.5
TCGA-H6-A45N-01A	88 years, female, white, stage:iib, dead, 421 days	714.8
TCGA-2J-AABK-01A	71 years, male, white, stage:iib, alive, 484 days	707.3
TCGA-FB-AAQ1-01A	49 years, male, white, stage:iib, dead, 123 days	704.0
TCGA-2L-AAQE-01A	56 years, male, white, stage:iib, dead, 684 days	702.6
TCGA-HZ-A9TJ-01A	70 years, male, white, stage:iv, alive, 603 days	700.1
TCGA-3A-A9IZ-01A	47 years, male, white, stage:iib, dead, 308 days	698.9
TCGA-S4-A8RM-01A	67 years, male, white, stage:iib, alive, 737 days	698.6
TCGA-FB-AAPZ-01A	54 years, male, white, stage:iib, alive, 716 days	693.2
TCGA-LB-A8F3-01A	64 years, female, black or african american, stage:iia, alive, 379 days	692.2
TCGA-HZ-8005-01A	81 years, male, white, stage:iib, dead, 120 days	689.1
TCGA-2J-AABA-01A	55 years, male, white, stage:iib, dead, 607 days	687.1
TCGA-IB-A6UF-01A	63 years, male, white, stage:iib, alive, 666 days	686.5
TCGA-XD-AAUH-01A	57 years, female, white, stage:iib, alive, 395 days	679.9
TCGA-RB-A7B8-01A	81 years, female, white, stage:iib, dead, 466 days	677.4
TCGA-HZ-8003-01A	65 years, female, white, stage:iib, dead, 596 days	676.6
TCGA-XD-AAUI-01A	50 years, female, white, stage:iib, dead, 366 days	659.9
TCGA-FB-A78T-01A	71 years, female, white, stage:iib, dead, 375 days	659.2
TCGA-IB-AAUV-01A	49 years, male, white, stage:iib, alive, 404 days	650.5
TCGA-2L-AAQA-01A	76 years, male, white, stage:iib, dead, 143 days	650.5
TCGA-IB-A7M4-01A	81 years, male, white, stage:iib, alive, 483 days	646.9
TCGA-IB-7644-01A	65 years, female, white, stage:iv, dead, 394 days	639.8
TCGA-HZ-7926-01A	57 years, male, black or african american, stage:iib, dead, 518 days	636.2
TCGA-HV-A5A6-01A	65 years, female, asian, stage:iib, dead, 2036 days	634.6
TCGA-HZ-A8P1-01A	81 years, male, white, stage:ib, alive, 7 days	630.0
TCGA-FB-AAPU-01A	41 years, female, asian, stage:iia, dead, 381 days	629.4
TCGA-HV-AA8V-01A	50 years, male, asian, stage:iib, alive, 920 days	622.7
TCGA-3A-A9IX-01A	40 years, male, white, stage:ia, alive, 1037 days	622.6
TCGA-2J-AABI-01A	55 years, female, white, stage:iia, alive, 969 days	622.5
TCGA-HZ-8317-01A	69 years, female, white, stage:iib, dead, 378 days	622.1
TCGA-HZ-A77P-01A	77 years, male, white, stage:iib, alive, 330 days	603.1
TCGA-2J-AAB9-01A	71 years, female, white, stage:iib, dead, 627 days	600.5
TCGA-XN-A8T3-01A	67 years, male, white, stage:ib, alive, 951 days	582.8
TCGA-2J-AABE-01A	73 years, male, white, stage:iia, alive, 676 days	575.3
TCGA-2J-AABH-01A	61 years, male, white, stage:iia, alive, 1287 days	568.2
TCGA-3A-A9IL-01A	39 years, female, white, stage:i, alive, 2741 days	561.2
TCGA-3E-AAAZ-01A	71 years, male, white, stage:iia, dead, 2182 days	551.9
TCGA-IB-7890-01A	73 years, male, stage:ib, dead, 598 days	533.6
TCGA-FB-AAQ2-01A	81 years, female, white, stage:iib, dead, 153 days	532.7
TCGA-F2-A44H-01A	65 years, male, white, stage:iia, alive, 586 days	528.7
TCGA-3A-A9I9-01A	67 years, male, white, stage:iia, dead, 634 days	528.3
TCGA-XD-AAUG-01A	66 years, female, white, stage:iv, alive, 420 days	515.7
TCGA-H6-8124-01A	56 years, female, white, stage:iib, alive, 392 days	514.4
TCGA-LB-A9Q5-01A	63 years, female, white, stage:iib, dead, 313 days	509.6
TCGA-IB-8126-01A	80 years, female, white, stage:iii, alive, 462 days	487.8
TCGA-US-A779-01A	54 years, female, white, stage:iib, dead, 511 days	466.6
TCGA-2J-AABT-01A	72 years, female, white, stage:iib, alive, 319 days	463.2
TCGA-HV-A5A3-01A	50 years, male, asian, stage:iia, dead, 128 days	453.2
TCGA-3A-A9I5-01A	58 years, male, white, alive, 1794 days	447.2
TCGA-FB-AAPP-01A	71 years, male, white, stage:iib, dead, 485 days	419.8
TCGA-FB-A545-01A	72 years, female, white, stage:iib, dead, 732 days	411.0
TCGA-IB-A7LX-01A	57 years, male, white, stage:iib, dead, 250 days	395.3
TCGA-IB-A6UG-01A	65 years, male, white, stage:iib, dead, 41 days	370.2
TCGA-3A-A9IO-01A	56 years, male, white, alive, 1942 days	345.5
TCGA-HZ-7289-01A	77 years, male, white, stage:iib, dead, 661 days	344.0
TCGA-3A-A9IN-01A	62 years, female, white, stage:ib, alive, 2084 days	340.8
TCGA-3A-A9IR-01A	64 years, female, white, stage:ib, alive, 1542 days	340.5
TCGA-3A-A9IV-01A	59 years, female, white, stage:ib, alive, 1103 days	338.9
TCGA-L1-A7W4-01A	48 years, female, white, stage:iib, dead, 278 days	335.7
TCGA-IB-AAUM-01A	76 years, male, white, stage:iib, alive, 8 days	316.6
TCGA-3A-A9IJ-01A	65 years, male, white, stage:ib, alive, 1854 days	244.8
TCGA-2L-AAQM-01A	52 years, male, white, stage:iib, alive, 1383 days	234.2
TCGA-3A-A9IS-01A	67 years, male, white, stage:ib, alive, 998 days	190.9
TCGA-2J-AABV-01A	74 years, male, white, stage:iib, dead, 652 days	149.9
TCGA-HV-A7OP-01A	72 years, male, asian, stage:iib, alive, 978 days	116.3
TCGA-F2-6880-01A	70 years, male, white, stage:iib, alive, 289 days	100.3
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PANCREATIC CANCER - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high. This score is based on the staining intensity and fraction of stained cells. Read more	Antibody HPA006361	Antibody CAB002572
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Click images for details