Cell type atlas - NUDT5 - The Human Protein Atlas

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NUDT5

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	NUDT5
Gene descriptionⁱ Full gene name according to HGNC.	Nudix hydrolase 5
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Enzymes Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	6

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	24 NX
Lung	24 NX

Alveolar cells type 2	38 NX
Lung	38 NX

B-cells	34 NX
Liver	73 NX
Kidney	36 NX
Colon	31 NX

Basal glandular cells	51 NX
Prostate	51 NX

Basal keratinocytes	38 NX
Skin	38 NX

Bipolar cells	19 NX
Eye	19 NX

Cardiomyocytes	3 NX
Heart muscle	3 NX

Cholangiocytes	26 NX
Liver	26 NX

Ciliated cells	60 NX
Lung	60 NX

Club cells	40 NX
Lung	40 NX

Collecting duct cells	23 NX
Kidney	23 NX

Cone photoreceptor cells	16 NX
Eye	16 NX

Cytotrophoblasts	74 NX
Placenta	74 NX

Distal tubular cells	63 NX
Kidney	63 NX

Ductal cells	74 NX
Pancreas	74 NX

Early spermatids	27 NX
Testis	27 NX

Endothelial cells	31 NX
Placenta	78 NX
Pancreas	72 NX
Eye	44 NX
Testis	41 NX
Liver	32 NX
Skin	30 NX
Prostate	25 NX
Heart muscle	24 NX
Lung	23 NX

Enterocytes	34 NX
Small intestine	42 NX
Rectum	32 NX
Colon	28 NX

Erythroid cells	23 NX
Liver	23 NX

Exocrine glandular cells	72 NX
Pancreas	72 NX

Extravillous trophoblasts	128 NX
Placenta	128 NX

Fibroblasts	36 NX
Placenta	72 NX
Lung	46 NX
Prostate	36 NX
Heart muscle	26 NX
Skin	24 NX

Glandular cells	31 NX
Prostate	30 NX

Granulocytes	31 NX
Colon	37 NX
Lung	26 NX

Hepatocytes	117 NX
Liver	117 NX

Hofbauer cells	105 NX
Placenta	105 NX

Horizontal cells	21 NX
Eye	21 NX

Intestinal endocrine cells	37 NX
Colon	41 NX
Rectum	33 NX

Ito cells	41 NX
Liver	41 NX

Kupffer cells	41 NX
Liver	41 NX

Late spermatids	7 NX
Testis	7 NX

Leydig cells	37 NX
Testis	37 NX

Macrophages	39 NX
Pancreas	73 NX
Kidney	67 NX
Testis	47 NX
Lung	38 NX
Prostate	35 NX
Skin	32 NX

Melanocytes	29 NX
Skin	29 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	110 NX
Pancreas	110 NX

Mucus-secreting cells	35 NX
Small intestine	37 NX
Colon	36 NX
Rectum	33 NX

Muller glia cells	33 NX
Eye	33 NX

Pancreatic endocrine cells	65 NX
Pancreas	65 NX

Paneth cells	28 NX
Rectum	48 NX
Small intestine	28 NX
Colon	20 NX

Peritubular cells	27 NX
Testis	27 NX

Proximal tubular cells	96 NX
Kidney	96 NX

Rod photoreceptor cells	23 NX
Eye	23 NX

Sertoli cells	32 NX
Testis	32 NX

Smooth muscle cells	26 NX
Pancreas	109 NX
Heart muscle	30 NX
Prostate	26 NX
Skin	21 NX

Spermatocytes	20 NX
Testis	20 NX

Spermatogonia	28 NX
Testis	28 NX

Suprabasal keratinocytes	53 NX
Skin	53 NX

Syncytiotrophoblasts	49 NX
Placenta	49 NX

T-cells	52 NX
Kidney	78 NX
Liver	53 NX
Skin	52 NX
Prostate	52 NX
Lung	48 NX
Colon	48 NX

Undifferentiated cells	51 NX
Small intestine	59 NX
Colon	51 NX
Rectum	41 NX

Urothelial cells	41 NX
Prostate	41 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.