Cell type atlas - NDUFB6 - The Human Protein Atlas

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NDUFB6

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	NDUFB6
Gene descriptionⁱ Full gene name according to HGNC.	NADH:ubiquinone oxidoreductase subunit B6
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular,Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	3

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Early spermatids)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Early spermatids)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	116 NX
Lung	116 NX

Alveolar cells type 2	94 NX
Lung	94 NX

B-cells	77 NX
Liver	135 NX
Kidney	89 NX
Colon	66 NX

Basal glandular cells	81 NX
Prostate	81 NX

Basal keratinocytes	84 NX
Skin	84 NX

Bipolar cells	39 NX
Eye	39 NX

Cardiomyocytes	514 NX
Heart muscle	514 NX

Cholangiocytes	107 NX
Liver	107 NX

Ciliated cells	155 NX
Lung	155 NX

Club cells	108 NX
Lung	108 NX

Collecting duct cells	103 NX
Kidney	103 NX

Cone photoreceptor cells	6 NX
Eye	6 NX

Cytotrophoblasts	176 NX
Placenta	176 NX

Distal tubular cells	453 NX
Kidney	453 NX

Ductal cells	144 NX
Pancreas	144 NX

Early spermatids	591 NX
Testis	591 NX

Endothelial cells	96 NX
Pancreas	201 NX
Heart muscle	136 NX
Placenta	133 NX
Testis	97 NX
Lung	96 NX
Skin	83 NX
Prostate	63 NX
Liver	59 NX
Eye	54 NX

Enterocytes	139 NX
Small intestine	174 NX
Rectum	104 NX
Colon	94 NX

Erythroid cells	94 NX
Liver	94 NX

Exocrine glandular cells	145 NX
Pancreas	145 NX

Extravillous trophoblasts	113 NX
Placenta	113 NX

Fibroblasts	93 NX
Heart muscle	255 NX
Placenta	137 NX
Skin	92 NX
Lung	69 NX
Prostate	50 NX

Glandular cells	79 NX
Prostate	79 NX

Granulocytes	87 NX
Lung	109 NX
Colon	64 NX

Hepatocytes	170 NX
Liver	170 NX

Hofbauer cells	142 NX
Placenta	142 NX

Horizontal cells	18 NX
Eye	18 NX

Intestinal endocrine cells	62 NX
Colon	75 NX
Rectum	49 NX

Ito cells	72 NX
Liver	72 NX

Kupffer cells	60 NX
Liver	60 NX

Late spermatids	89 NX
Testis	89 NX

Leydig cells	85 NX
Testis	85 NX

Macrophages	90 NX
Pancreas	171 NX
Lung	146 NX
Kidney	127 NX
Skin	84 NX
Testis	83 NX
Prostate	57 NX

Melanocytes	152 NX
Skin	152 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	112 NX
Pancreas	112 NX

Mucus-secreting cells	117 NX
Colon	172 NX
Rectum	122 NX
Small intestine	97 NX

Muller glia cells	72 NX
Eye	72 NX

Pancreatic endocrine cells	133 NX
Pancreas	133 NX

Paneth cells	119 NX
Small intestine	126 NX
Rectum	119 NX
Colon	95 NX

Peritubular cells	85 NX
Testis	85 NX

Proximal tubular cells	441 NX
Kidney	441 NX

Rod photoreceptor cells	41 NX
Eye	41 NX

Sertoli cells	104 NX
Testis	104 NX

Smooth muscle cells	125 NX
Heart muscle	265 NX
Pancreas	169 NX
Skin	117 NX
Prostate	65 NX

Spermatocytes	144 NX
Testis	144 NX

Spermatogonia	114 NX
Testis	114 NX

Suprabasal keratinocytes	85 NX
Skin	85 NX

Syncytiotrophoblasts	87 NX
Placenta	87 NX

T-cells	65 NX
Skin	112 NX
Kidney	106 NX
Lung	96 NX
Prostate	65 NX
Liver	60 NX
Colon	50 NX

Undifferentiated cells	146 NX
Colon	186 NX
Rectum	157 NX
Small intestine	135 NX

Urothelial cells	88 NX
Prostate	88 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.