Cell type atlas - RPS14 - The Human Protein Atlas

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RPS14

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RPS14
Gene descriptionⁱ Full gene name according to HGNC.	Ribosomal protein S14
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Plasma proteins Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	5

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	1242 NX
Lung	1242 NX

Alveolar cells type 2	2224 NX
Lung	2224 NX

B-cells	5848 NX
Kidney	7521 NX
Liver	5848 NX
Colon	1489 NX

Basal glandular cells	7839 NX
Prostate	7839 NX

Basal keratinocytes	10367 NX
Skin	10367 NX

Bipolar cells	470 NX
Eye	470 NX

Cardiomyocytes	1739 NX
Heart muscle	1739 NX

Cholangiocytes	3103 NX
Liver	3103 NX

Ciliated cells	1475 NX
Lung	1475 NX

Club cells	2518 NX
Lung	2518 NX

Collecting duct cells	1403 NX
Kidney	1403 NX

Cone photoreceptor cells	175 NX
Eye	175 NX

Cytotrophoblasts	6157 NX
Placenta	6157 NX

Distal tubular cells	3836 NX
Kidney	3836 NX

Ductal cells	2863 NX
Pancreas	2863 NX

Early spermatids	930 NX
Testis	930 NX

Endothelial cells	4248 NX
Skin	8675 NX
Prostate	5762 NX
Liver	5210 NX
Placenta	4887 NX
Testis	4248 NX
Pancreas	2220 NX
Heart muscle	1873 NX
Lung	1753 NX
Eye	1489 NX

Enterocytes	1997 NX
Small intestine	4621 NX
Rectum	2134 NX
Colon	1952 NX

Erythroid cells	1495 NX
Liver	1495 NX

Exocrine glandular cells	7589 NX
Pancreas	7589 NX

Extravillous trophoblasts	7325 NX
Placenta	7325 NX

Fibroblasts	4606 NX
Skin	5527 NX
Placenta	4514 NX
Lung	3681 NX
Prostate	3064 NX
Heart muscle	2037 NX

Glandular cells	5277 NX
Prostate	5277 NX

Granulocytes	2165 NX
Lung	3348 NX
Colon	983 NX

Hepatocytes	3417 NX
Liver	3417 NX

Hofbauer cells	4102 NX
Placenta	4102 NX

Horizontal cells	192 NX
Eye	192 NX

Intestinal endocrine cells	2301 NX
Rectum	3459 NX
Colon	1142 NX

Ito cells	3299 NX
Liver	3299 NX

Kupffer cells	4925 NX
Liver	4925 NX

Late spermatids	1359 NX
Testis	1359 NX

Leydig cells	4034 NX
Testis	4034 NX

Macrophages	6269 NX
Skin	8013 NX
Prostate	6734 NX
Kidney	6315 NX
Testis	6223 NX
Lung	2769 NX
Pancreas	1713 NX

Melanocytes	6141 NX
Skin	6141 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	5452 NX
Pancreas	5452 NX

Mucus-secreting cells	4847 NX
Rectum	8191 NX
Small intestine	4720 NX
Colon	2411 NX

Muller glia cells	752 NX
Eye	752 NX

Pancreatic endocrine cells	5032 NX
Pancreas	5032 NX

Paneth cells	4335 NX
Rectum	6436 NX
Small intestine	4335 NX
Colon	2194 NX

Peritubular cells	2101 NX
Testis	2101 NX

Proximal tubular cells	3825 NX
Kidney	3825 NX

Rod photoreceptor cells	499 NX
Eye	499 NX

Sertoli cells	1578 NX
Testis	1578 NX

Smooth muscle cells	4451 NX
Skin	6711 NX
Prostate	4451 NX
Pancreas	3183 NX
Heart muscle	2347 NX

Spermatocytes	718 NX
Testis	718 NX

Spermatogonia	799 NX
Testis	799 NX

Suprabasal keratinocytes	13425 NX
Skin	13425 NX

Syncytiotrophoblasts	5960 NX
Placenta	5960 NX

T-cells	3923 NX
Skin	9365 NX
Kidney	8066 NX
Prostate	5714 NX
Liver	3802 NX
Lung	3625 NX
Colon	1269 NX

Undifferentiated cells	6829 NX
Small intestine	7320 NX
Rectum	6947 NX
Colon	1615 NX

Urothelial cells	8561 NX
Prostate	8561 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.