Cell type atlas - NSA2 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

NSA2

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	NSA2
Gene descriptionⁱ Full gene name according to HGNC.	NSA2, ribosome biogenesis homolog
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Plasma proteins Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	3

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	75 NX
Lung	75 NX

Alveolar cells type 2	77 NX
Lung	77 NX

B-cells	156 NX
Liver	201 NX
Colon	185 NX
Kidney	116 NX

Basal glandular cells	141 NX
Prostate	141 NX

Basal keratinocytes	84 NX
Skin	84 NX

Bipolar cells	32 NX
Eye	32 NX

Cardiomyocytes	80 NX
Heart muscle	80 NX

Cholangiocytes	138 NX
Liver	138 NX

Ciliated cells	67 NX
Lung	67 NX

Club cells	105 NX
Lung	105 NX

Collecting duct cells	59 NX
Kidney	59 NX

Cone photoreceptor cells	14 NX
Eye	14 NX

Cytotrophoblasts	119 NX
Placenta	119 NX

Distal tubular cells	128 NX
Kidney	128 NX

Ductal cells	114 NX
Pancreas	114 NX

Early spermatids	331 NX
Testis	331 NX

Endothelial cells	86 NX
Testis	159 NX
Liver	124 NX
Pancreas	111 NX
Placenta	105 NX
Prostate	92 NX
Eye	86 NX
Lung	70 NX
Skin	56 NX
Heart muscle	31 NX

Enterocytes	114 NX
Small intestine	125 NX
Colon	113 NX
Rectum	76 NX

Erythroid cells	117 NX
Liver	117 NX

Exocrine glandular cells	205 NX
Pancreas	205 NX

Extravillous trophoblasts	170 NX
Placenta	170 NX

Fibroblasts	84 NX
Lung	131 NX
Placenta	110 NX
Prostate	84 NX
Skin	68 NX
Heart muscle	57 NX

Glandular cells	111 NX
Prostate	111 NX

Granulocytes	117 NX
Colon	129 NX
Lung	105 NX

Hepatocytes	185 NX
Liver	185 NX

Hofbauer cells	122 NX
Placenta	122 NX

Horizontal cells	48 NX
Eye	48 NX

Intestinal endocrine cells	134 NX
Colon	139 NX
Rectum	129 NX

Ito cells	114 NX
Liver	114 NX

Kupffer cells	170 NX
Liver	170 NX

Late spermatids	102 NX
Testis	102 NX

Leydig cells	258 NX
Testis	258 NX

Macrophages	109 NX
Testis	282 NX
Prostate	138 NX
Kidney	132 NX
Lung	109 NX
Skin	94 NX
Pancreas	87 NX

Melanocytes	79 NX
Skin	79 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	150 NX
Pancreas	150 NX

Mucus-secreting cells	219 NX
Colon	250 NX
Rectum	242 NX
Small intestine	131 NX

Muller glia cells	47 NX
Eye	47 NX

Pancreatic endocrine cells	172 NX
Pancreas	172 NX

Paneth cells	119 NX
Rectum	182 NX
Small intestine	119 NX
Colon	101 NX

Peritubular cells	161 NX
Testis	161 NX

Proximal tubular cells	158 NX
Kidney	158 NX

Rod photoreceptor cells	31 NX
Eye	31 NX

Sertoli cells	136 NX
Testis	136 NX

Smooth muscle cells	91 NX
Pancreas	127 NX
Prostate	114 NX
Skin	86 NX
Heart muscle	86 NX

Spermatocytes	121 NX
Testis	121 NX

Spermatogonia	95 NX
Testis	95 NX

Suprabasal keratinocytes	75 NX
Skin	75 NX

Syncytiotrophoblasts	113 NX
Placenta	113 NX

T-cells	107 NX
Colon	145 NX
Prostate	131 NX
Liver	112 NX
Kidney	107 NX
Skin	105 NX
Lung	98 NX

Undifferentiated cells	207 NX
Colon	223 NX
Rectum	209 NX
Small intestine	199 NX

Urothelial cells	165 NX
Prostate	165 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.