Cell type atlas - CGGBP1 - The Human Protein Atlas

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CGGBP1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	CGGBP1
Gene descriptionⁱ Full gene name according to HGNC.	CGG triplet repeat binding protein 1
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	5

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (U-2197)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	48 NX
Lung	48 NX

Alveolar cells type 2	40 NX
Lung	40 NX

B-cells	46 NX
Colon	64 NX
Kidney	40 NX
Liver	32 NX

Basal glandular cells	57 NX
Prostate	57 NX

Basal keratinocytes	47 NX
Skin	47 NX

Bipolar cells	33 NX
Eye	33 NX

Cardiomyocytes	40 NX
Heart muscle	40 NX

Cholangiocytes	36 NX
Liver	36 NX

Ciliated cells	16 NX
Lung	16 NX

Club cells	47 NX
Lung	47 NX

Collecting duct cells	38 NX
Kidney	38 NX

Cone photoreceptor cells	16 NX
Eye	16 NX

Cytotrophoblasts	48 NX
Placenta	48 NX

Distal tubular cells	56 NX
Kidney	56 NX

Ductal cells	34 NX
Pancreas	34 NX

Early spermatids	16 NX
Testis	16 NX

Endothelial cells	65 NX
Heart muscle	80 NX
Prostate	72 NX
Skin	71 NX
Testis	67 NX
Liver	65 NX
Pancreas	65 NX
Eye	38 NX
Placenta	33 NX
Lung	29 NX

Enterocytes	42 NX
Colon	50 NX
Rectum	42 NX
Small intestine	35 NX

Erythroid cells	23 NX
Liver	23 NX

Exocrine glandular cells	36 NX
Pancreas	36 NX

Extravillous trophoblasts	52 NX
Placenta	52 NX

Fibroblasts	55 NX
Skin	67 NX
Heart muscle	64 NX
Prostate	55 NX
Placenta	36 NX
Lung	23 NX

Glandular cells	58 NX
Prostate	58 NX

Granulocytes	45 NX
Lung	54 NX
Colon	37 NX

Hepatocytes	49 NX
Liver	49 NX

Hofbauer cells	36 NX
Placenta	36 NX

Horizontal cells	64 NX
Eye	64 NX

Intestinal endocrine cells	40 NX
Colon	48 NX
Rectum	33 NX

Ito cells	61 NX
Liver	61 NX

Kupffer cells	46 NX
Liver	46 NX

Late spermatids	29 NX
Testis	29 NX

Leydig cells	65 NX
Testis	65 NX

Macrophages	53 NX
Skin	60 NX
Prostate	60 NX
Testis	55 NX
Kidney	54 NX
Lung	44 NX
Pancreas	35 NX

Melanocytes	39 NX
Skin	39 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	34 NX
Pancreas	34 NX

Mucus-secreting cells	30 NX
Colon	43 NX
Rectum	31 NX
Small intestine	28 NX

Muller glia cells	62 NX
Eye	62 NX

Pancreatic endocrine cells	41 NX
Pancreas	41 NX

Paneth cells	35 NX
Colon	52 NX
Rectum	35 NX
Small intestine	32 NX

Peritubular cells	47 NX
Testis	47 NX

Proximal tubular cells	53 NX
Kidney	53 NX

Rod photoreceptor cells	30 NX
Eye	30 NX

Sertoli cells	65 NX
Testis	65 NX

Smooth muscle cells	69 NX
Heart muscle	82 NX
Prostate	70 NX
Skin	67 NX
Pancreas	48 NX

Spermatocytes	82 NX
Testis	82 NX

Spermatogonia	49 NX
Testis	49 NX

Suprabasal keratinocytes	44 NX
Skin	44 NX

Syncytiotrophoblasts	70 NX
Placenta	70 NX

T-cells	69 NX
Skin	95 NX
Prostate	83 NX
Kidney	75 NX
Lung	69 NX
Colon	67 NX
Liver	59 NX

Undifferentiated cells	32 NX
Colon	34 NX
Rectum	32 NX
Small intestine	31 NX

Urothelial cells	58 NX
Prostate	58 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.