Cell type atlas - MRPS18C - The Human Protein Atlas

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MRPS18C

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	MRPS18C
Gene descriptionⁱ Full gene name according to HGNC.	Mitochondrial ribosomal protein S18C
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	5

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	48 NX
Lung	48 NX

Alveolar cells type 2	54 NX
Lung	54 NX

B-cells	85 NX
Kidney	129 NX
Liver	81 NX
Colon	40 NX

Basal glandular cells	65 NX
Prostate	65 NX

Basal keratinocytes	61 NX
Skin	61 NX

Bipolar cells	33 NX
Eye	33 NX

Cardiomyocytes	84 NX
Heart muscle	84 NX

Cholangiocytes	89 NX
Liver	89 NX

Ciliated cells	84 NX
Lung	84 NX

Club cells	42 NX
Lung	42 NX

Collecting duct cells	73 NX
Kidney	73 NX

Cone photoreceptor cells	35 NX
Eye	35 NX

Cytotrophoblasts	111 NX
Placenta	111 NX

Distal tubular cells	194 NX
Kidney	194 NX

Ductal cells	97 NX
Pancreas	97 NX

Early spermatids	63 NX
Testis	63 NX

Endothelial cells	69 NX
Pancreas	118 NX
Testis	100 NX
Placenta	85 NX
Lung	85 NX
Liver	85 NX
Skin	63 NX
Prostate	56 NX
Eye	56 NX
Heart muscle	43 NX

Enterocytes	59 NX
Small intestine	88 NX
Colon	48 NX
Rectum	47 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	163 NX
Pancreas	163 NX

Extravillous trophoblasts	99 NX
Placenta	99 NX

Fibroblasts	57 NX
Placenta	74 NX
Heart muscle	69 NX
Lung	57 NX
Skin	49 NX
Prostate	45 NX

Glandular cells	49 NX
Prostate	49 NX

Granulocytes	105 NX
Lung	128 NX
Colon	83 NX

Hepatocytes	147 NX
Liver	147 NX

Hofbauer cells	99 NX
Placenta	99 NX

Horizontal cells	30 NX
Eye	30 NX

Intestinal endocrine cells	32 NX
Colon	34 NX
Rectum	31 NX

Ito cells	70 NX
Liver	70 NX

Kupffer cells	59 NX
Liver	59 NX

Late spermatids	14 NX
Testis	14 NX

Leydig cells	76 NX
Testis	76 NX

Macrophages	65 NX
Pancreas	103 NX
Kidney	93 NX
Lung	87 NX
Testis	70 NX
Skin	48 NX
Prostate	35 NX

Melanocytes	59 NX
Skin	59 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	52 NX
Pancreas	52 NX

Mucus-secreting cells	52 NX
Rectum	59 NX
Colon	55 NX
Small intestine	45 NX

Muller glia cells	49 NX
Eye	49 NX

Pancreatic endocrine cells	111 NX
Pancreas	111 NX

Paneth cells	76 NX
Small intestine	102 NX
Rectum	76 NX
Colon	52 NX

Peritubular cells	73 NX
Testis	73 NX

Proximal tubular cells	145 NX
Kidney	145 NX

Rod photoreceptor cells	48 NX
Eye	48 NX

Sertoli cells	58 NX
Testis	58 NX

Smooth muscle cells	63 NX
Pancreas	118 NX
Skin	64 NX
Heart muscle	47 NX
Prostate	43 NX

Spermatocytes	107 NX
Testis	107 NX

Spermatogonia	60 NX
Testis	60 NX

Suprabasal keratinocytes	56 NX
Skin	56 NX

Syncytiotrophoblasts	80 NX
Placenta	80 NX

T-cells	63 NX
Kidney	99 NX
Liver	66 NX
Lung	65 NX
Skin	55 NX
Colon	46 NX
Prostate	35 NX

Undifferentiated cells	73 NX
Colon	79 NX
Small intestine	73 NX
Rectum	69 NX

Urothelial cells	55 NX
Prostate	55 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.