Cell type atlas - CDC42EP3 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

CDC42EP3

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	CDC42EP3
Gene descriptionⁱ Full gene name according to HGNC.	CDC42 effector protein 3
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	5

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Melanocytes)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in many
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (LHCN-M2)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Melanocytes)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	6 NX
Lung	6 NX

Alveolar cells type 2	37 NX
Lung	37 NX

B-cells	26 NX
Kidney	58 NX
Colon	37 NX
Liver	7 NX

Basal glandular cells	94 NX
Prostate	94 NX

Basal keratinocytes	33 NX
Skin	33 NX

Bipolar cells	8 NX
Eye	8 NX

Cardiomyocytes	91 NX
Heart muscle	91 NX

Cholangiocytes	13 NX
Liver	13 NX

Ciliated cells	83 NX
Lung	83 NX

Club cells	18 NX
Lung	18 NX

Collecting duct cells	30 NX
Kidney	30 NX

Cone photoreceptor cells	33 NX
Eye	33 NX

Cytotrophoblasts	24 NX
Placenta	24 NX

Distal tubular cells	8 NX
Kidney	8 NX

Ductal cells	20 NX
Pancreas	20 NX

Early spermatids	42 NX
Testis	42 NX

Endothelial cells	52 NX
Prostate	347 NX
Skin	97 NX
Liver	88 NX
Pancreas	65 NX
Testis	59 NX
Lung	50 NX
Heart muscle	50 NX
Placenta	25 NX
Eye	25 NX

Enterocytes	3 NX
Rectum	9 NX
Colon	4 NX
Small intestine	1 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	14 NX
Pancreas	14 NX

Extravillous trophoblasts	59 NX
Placenta	59 NX

Fibroblasts	27 NX
Prostate	83 NX
Placenta	34 NX
Lung	26 NX
Heart muscle	18 NX
Skin	14 NX

Glandular cells	25 NX
Prostate	25 NX

Granulocytes	130 NX
Colon	202 NX
Lung	58 NX

Hepatocytes	1 NX
Liver	1 NX

Hofbauer cells	11 NX
Placenta	11 NX

Horizontal cells	95 NX
Eye	95 NX

Intestinal endocrine cells	40 NX
Colon	51 NX
Rectum	28 NX

Ito cells	55 NX
Liver	55 NX

Kupffer cells	42 NX
Liver	42 NX

Late spermatids	92 NX
Testis	92 NX

Leydig cells	14 NX
Testis	14 NX

Macrophages	53 NX
Prostate	212 NX
Skin	153 NX
Lung	66 NX
Kidney	48 NX
Testis	44 NX
Pancreas	7 NX

Melanocytes	191 NX
Skin	191 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	2 NX
Pancreas	2 NX

Mucus-secreting cells	37 NX
Small intestine	58 NX
Colon	41 NX
Rectum	33 NX

Muller glia cells	27 NX
Eye	27 NX

Pancreatic endocrine cells	18 NX
Pancreas	18 NX

Paneth cells	4 NX
Rectum	5 NX
Small intestine	4 NX
Colon	0 NX

Peritubular cells	119 NX
Testis	119 NX

Proximal tubular cells	4 NX
Kidney	4 NX

Rod photoreceptor cells	12 NX
Eye	12 NX

Sertoli cells	0 NX
Testis	0 NX

Smooth muscle cells	19 NX
Prostate	69 NX
Pancreas	19 NX
Skin	17 NX
Heart muscle	14 NX

Spermatocytes	64 NX
Testis	64 NX

Spermatogonia	13 NX
Testis	13 NX

Suprabasal keratinocytes	12 NX
Skin	12 NX

Syncytiotrophoblasts	10 NX
Placenta	10 NX

T-cells	74 NX
Prostate	336 NX
Kidney	79 NX
Skin	78 NX
Colon	74 NX
Lung	43 NX
Liver	22 NX

Undifferentiated cells	6 NX
Rectum	8 NX
Colon	6 NX
Small intestine	1 NX

Urothelial cells	35 NX
Prostate	35 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.