Cell type atlas - RPL8 - The Human Protein Atlas

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RPL8

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RPL8
Gene descriptionⁱ Full gene name according to HGNC.	Ribosomal protein L8
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Plasma proteins Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	6

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (MCF7)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	792 NX
Lung	792 NX

Alveolar cells type 2	1173 NX
Lung	1173 NX

B-cells	3640 NX
Kidney	5921 NX
Liver	3640 NX
Colon	1310 NX

Basal glandular cells	5704 NX
Prostate	5704 NX

Basal keratinocytes	5720 NX
Skin	5720 NX

Bipolar cells	400 NX
Eye	400 NX

Cardiomyocytes	927 NX
Heart muscle	927 NX

Cholangiocytes	1595 NX
Liver	1595 NX

Ciliated cells	668 NX
Lung	668 NX

Club cells	1240 NX
Lung	1240 NX

Collecting duct cells	975 NX
Kidney	975 NX

Cone photoreceptor cells	253 NX
Eye	253 NX

Cytotrophoblasts	3838 NX
Placenta	3838 NX

Distal tubular cells	3757 NX
Kidney	3757 NX

Ductal cells	1939 NX
Pancreas	1939 NX

Early spermatids	709 NX
Testis	709 NX

Endothelial cells	1998 NX
Skin	4974 NX
Prostate	4609 NX
Placenta	2649 NX
Testis	2635 NX
Liver	1998 NX
Pancreas	1522 NX
Eye	1018 NX
Lung	785 NX
Heart muscle	588 NX

Enterocytes	1896 NX
Small intestine	3015 NX
Colon	1835 NX
Rectum	1492 NX

Erythroid cells	1261 NX
Liver	1261 NX

Exocrine glandular cells	5072 NX
Pancreas	5072 NX

Extravillous trophoblasts	5915 NX
Placenta	5915 NX

Fibroblasts	2685 NX
Skin	2956 NX
Placenta	2716 NX
Prostate	2447 NX
Lung	1557 NX
Heart muscle	675 NX

Glandular cells	4293 NX
Prostate	4293 NX

Granulocytes	1005 NX
Lung	1202 NX
Colon	808 NX

Hepatocytes	1181 NX
Liver	1181 NX

Hofbauer cells	2698 NX
Placenta	2698 NX

Horizontal cells	157 NX
Eye	157 NX

Intestinal endocrine cells	1634 NX
Rectum	2238 NX
Colon	1030 NX

Ito cells	1478 NX
Liver	1478 NX

Kupffer cells	2283 NX
Liver	2283 NX

Late spermatids	2004 NX
Testis	2004 NX

Leydig cells	2892 NX
Testis	2892 NX

Macrophages	2666 NX
Prostate	3993 NX
Skin	3801 NX
Kidney	3796 NX
Testis	2534 NX
Pancreas	1256 NX
Lung	1097 NX

Melanocytes	3339 NX
Skin	3339 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	2696 NX
Pancreas	2696 NX

Mucus-secreting cells	3082 NX
Rectum	4746 NX
Small intestine	2878 NX
Colon	2236 NX

Muller glia cells	501 NX
Eye	501 NX

Pancreatic endocrine cells	3359 NX
Pancreas	3359 NX

Paneth cells	2949 NX
Rectum	3966 NX
Small intestine	2949 NX
Colon	2093 NX

Peritubular cells	1346 NX
Testis	1346 NX

Proximal tubular cells	3181 NX
Kidney	3181 NX

Rod photoreceptor cells	483 NX
Eye	483 NX

Sertoli cells	1061 NX
Testis	1061 NX

Smooth muscle cells	3223 NX
Skin	3504 NX
Prostate	3310 NX
Pancreas	2420 NX
Heart muscle	608 NX

Spermatocytes	573 NX
Testis	573 NX

Spermatogonia	570 NX
Testis	570 NX

Suprabasal keratinocytes	7189 NX
Skin	7189 NX

Syncytiotrophoblasts	3651 NX
Placenta	3651 NX

T-cells	2079 NX
Prostate	3596 NX
Skin	3499 NX
Kidney	3447 NX
Liver	1920 NX
Lung	1205 NX
Colon	1070 NX

Undifferentiated cells	4569 NX
Small intestine	4973 NX
Rectum	4580 NX
Colon	1571 NX

Urothelial cells	6042 NX
Prostate	6042 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.