Cell type atlas - ZDHHC12 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

ZDHHC12

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	ZDHHC12
Gene descriptionⁱ Full gene name according to HGNC.	Zinc finger DHHC-type containing 12
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Enzymes
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	4

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (MCF7)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	15 NX
Lung	15 NX

Alveolar cells type 2	8 NX
Lung	8 NX

B-cells	54 NX
Liver	66 NX
Colon	52 NX
Kidney	22 NX

Basal glandular cells	42 NX
Prostate	42 NX

Basal keratinocytes	14 NX
Skin	14 NX

Bipolar cells	1 NX
Eye	1 NX

Cardiomyocytes	10 NX
Heart muscle	10 NX

Cholangiocytes	79 NX
Liver	79 NX

Ciliated cells	4 NX
Lung	4 NX

Club cells	11 NX
Lung	11 NX

Collecting duct cells	44 NX
Kidney	44 NX

Cone photoreceptor cells	0 NX
Eye	0 NX

Cytotrophoblasts	147 NX
Placenta	147 NX

Distal tubular cells	12 NX
Kidney	12 NX

Ductal cells	95 NX
Pancreas	95 NX

Early spermatids	59 NX
Testis	59 NX

Endothelial cells	15 NX
Placenta	54 NX
Liver	29 NX
Testis	21 NX
Skin	15 NX
Pancreas	14 NX
Heart muscle	13 NX
Prostate	10 NX
Eye	10 NX
Lung	6 NX

Enterocytes	157 NX
Small intestine	162 NX
Rectum	156 NX
Colon	108 NX

Erythroid cells	70 NX
Liver	70 NX

Exocrine glandular cells	176 NX
Pancreas	176 NX

Extravillous trophoblasts	191 NX
Placenta	191 NX

Fibroblasts	11 NX
Placenta	44 NX
Skin	11 NX
Prostate	8 NX
Heart muscle	5 NX
Lung	2 NX

Glandular cells	50 NX
Prostate	50 NX

Granulocytes	18 NX
Colon	28 NX
Lung	9 NX

Hepatocytes	49 NX
Liver	49 NX

Hofbauer cells	121 NX
Placenta	121 NX

Horizontal cells	0 NX
Eye	0 NX

Intestinal endocrine cells	49 NX
Rectum	68 NX
Colon	31 NX

Ito cells	28 NX
Liver	28 NX

Kupffer cells	53 NX
Liver	53 NX

Late spermatids	22 NX
Testis	22 NX

Leydig cells	9 NX
Testis	9 NX

Macrophages	40 NX
Pancreas	178 NX
Prostate	64 NX
Testis	45 NX
Kidney	43 NX
Skin	27 NX
Lung	13 NX

Melanocytes	41 NX
Skin	41 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	160 NX
Pancreas	160 NX

Mucus-secreting cells	94 NX
Small intestine	130 NX
Colon	90 NX
Rectum	74 NX

Muller glia cells	15 NX
Eye	15 NX

Pancreatic endocrine cells	109 NX
Pancreas	109 NX

Paneth cells	172 NX
Colon	184 NX
Small intestine	172 NX
Rectum	98 NX

Peritubular cells	7 NX
Testis	7 NX

Proximal tubular cells	33 NX
Kidney	33 NX

Rod photoreceptor cells	2 NX
Eye	2 NX

Sertoli cells	7 NX
Testis	7 NX

Smooth muscle cells	10 NX
Pancreas	64 NX
Skin	11 NX
Prostate	9 NX
Heart muscle	6 NX

Spermatocytes	23 NX
Testis	23 NX

Spermatogonia	18 NX
Testis	18 NX

Suprabasal keratinocytes	25 NX
Skin	25 NX

Syncytiotrophoblasts	112 NX
Placenta	112 NX

T-cells	48 NX
Colon	56 NX
Kidney	55 NX
Liver	50 NX
Prostate	31 NX
Skin	19 NX
Lung	13 NX

Undifferentiated cells	94 NX
Colon	101 NX
Small intestine	94 NX
Rectum	81 NX

Urothelial cells	53 NX
Prostate	53 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.