Cell type atlas - BSDC1 - The Human Protein Atlas

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BSDC1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	BSDC1
Gene descriptionⁱ Full gene name according to HGNC.	BSD domain containing 1
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	7

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (basophil)
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	30 NX
Lung	30 NX

Alveolar cells type 2	15 NX
Lung	15 NX

B-cells	37 NX
Colon	66 NX
Kidney	54 NX
Liver	17 NX

Basal glandular cells	49 NX
Prostate	49 NX

Basal keratinocytes	25 NX
Skin	25 NX

Bipolar cells	49 NX
Eye	49 NX

Cardiomyocytes	17 NX
Heart muscle	17 NX

Cholangiocytes	36 NX
Liver	36 NX

Ciliated cells	15 NX
Lung	15 NX

Club cells	10 NX
Lung	10 NX

Collecting duct cells	24 NX
Kidney	24 NX

Cone photoreceptor cells	79 NX
Eye	79 NX

Cytotrophoblasts	43 NX
Placenta	43 NX

Distal tubular cells	17 NX
Kidney	17 NX

Ductal cells	32 NX
Pancreas	32 NX

Early spermatids	88 NX
Testis	88 NX

Endothelial cells	27 NX
Liver	70 NX
Prostate	58 NX
Testis	41 NX
Pancreas	32 NX
Eye	30 NX
Heart muscle	26 NX
Placenta	26 NX
Skin	23 NX
Lung	15 NX

Enterocytes	52 NX
Rectum	60 NX
Small intestine	56 NX
Colon	43 NX

Erythroid cells	70 NX
Liver	70 NX

Exocrine glandular cells	38 NX
Pancreas	38 NX

Extravillous trophoblasts	26 NX
Placenta	26 NX

Fibroblasts	26 NX
Prostate	66 NX
Skin	27 NX
Placenta	27 NX
Heart muscle	23 NX
Lung	19 NX

Glandular cells	52 NX
Prostate	52 NX

Granulocytes	21 NX
Colon	28 NX
Lung	14 NX

Hepatocytes	49 NX
Liver	49 NX

Hofbauer cells	18 NX
Placenta	18 NX

Horizontal cells	81 NX
Eye	81 NX

Intestinal endocrine cells	39 NX
Colon	44 NX
Rectum	33 NX

Ito cells	53 NX
Liver	53 NX

Kupffer cells	19 NX
Liver	19 NX

Late spermatids	79 NX
Testis	79 NX

Leydig cells	51 NX
Testis	51 NX

Macrophages	15 NX
Testis	34 NX
Pancreas	19 NX
Kidney	18 NX
Lung	15 NX
Prostate	15 NX
Skin	12 NX

Melanocytes	30 NX
Skin	30 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	26 NX
Pancreas	26 NX

Mucus-secreting cells	43 NX
Small intestine	50 NX
Rectum	45 NX
Colon	35 NX

Muller glia cells	36 NX
Eye	36 NX

Pancreatic endocrine cells	39 NX
Pancreas	39 NX

Paneth cells	32 NX
Rectum	48 NX
Small intestine	32 NX
Colon	29 NX

Peritubular cells	45 NX
Testis	45 NX

Proximal tubular cells	23 NX
Kidney	23 NX

Rod photoreceptor cells	67 NX
Eye	66 NX

Sertoli cells	39 NX
Testis	39 NX

Smooth muscle cells	26 NX
Heart muscle	68 NX
Prostate	43 NX
Skin	25 NX
Pancreas	24 NX

Spermatocytes	29 NX
Testis	29 NX

Spermatogonia	41 NX
Testis	41 NX

Suprabasal keratinocytes	23 NX
Skin	23 NX

Syncytiotrophoblasts	81 NX
Placenta	81 NX

T-cells	37 NX
Prostate	52 NX
Colon	51 NX
Liver	39 NX
Kidney	37 NX
Lung	22 NX
Skin	21 NX

Undifferentiated cells	36 NX
Rectum	41 NX
Small intestine	30 NX
Colon	26 NX

Urothelial cells	43 NX
Prostate	43 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.