Cell type atlas - EEF1A1 - The Human Protein Atlas

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EEF1A1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	EEF1A1
Gene descriptionⁱ Full gene name according to HGNC.	Eukaryotic translation elongation factor 1 alpha 1
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Cancer-related genes Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	7

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	2945 NX
Lung	2945 NX

Alveolar cells type 2	5105 NX
Lung	5105 NX

B-cells	7686 NX
Kidney	10194 NX
Liver	7722 NX
Colon	1714 NX

Basal glandular cells	9440 NX
Prostate	9440 NX

Basal keratinocytes	8732 NX
Skin	8732 NX

Bipolar cells	946 NX
Eye	946 NX

Cardiomyocytes	163 NX
Heart muscle	163 NX

Cholangiocytes	4538 NX
Liver	4538 NX

Ciliated cells	2578 NX
Lung	2578 NX

Club cells	4487 NX
Lung	4487 NX

Collecting duct cells	2502 NX
Kidney	2502 NX

Cone photoreceptor cells	514 NX
Eye	514 NX

Cytotrophoblasts	8108 NX
Placenta	8108 NX

Distal tubular cells	8765 NX
Kidney	8765 NX

Ductal cells	4837 NX
Pancreas	4837 NX

Early spermatids	1096 NX
Testis	1096 NX

Endothelial cells	6221 NX
Prostate	10573 NX
Testis	8436 NX
Skin	7727 NX
Liver	6565 NX
Placenta	6221 NX
Eye	3865 NX
Pancreas	2976 NX
Lung	2794 NX
Heart muscle	277 NX

Enterocytes	1774 NX
Small intestine	6209 NX
Rectum	2679 NX
Colon	1370 NX

Erythroid cells	1425 NX
Liver	1425 NX

Exocrine glandular cells	9008 NX
Pancreas	9008 NX

Extravillous trophoblasts	10118 NX
Placenta	10118 NX

Fibroblasts	6235 NX
Prostate	8068 NX
Placenta	6528 NX
Lung	6239 NX
Skin	6045 NX
Heart muscle	259 NX

Glandular cells	8188 NX
Prostate	8188 NX

Granulocytes	3507 NX
Lung	5811 NX
Colon	1203 NX

Hepatocytes	2998 NX
Liver	2998 NX

Hofbauer cells	5661 NX
Placenta	5661 NX

Horizontal cells	467 NX
Eye	467 NX

Intestinal endocrine cells	3719 NX
Rectum	6015 NX
Colon	1424 NX

Ito cells	4655 NX
Liver	4655 NX

Kupffer cells	6431 NX
Liver	6431 NX

Late spermatids	1731 NX
Testis	1731 NX

Leydig cells	8270 NX
Testis	8270 NX

Macrophages	6531 NX
Prostate	10400 NX
Testis	9609 NX
Skin	7389 NX
Kidney	6539 NX
Lung	4461 NX
Pancreas	1869 NX

Melanocytes	4849 NX
Skin	4849 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	19236 NX
Pancreas	19236 NX

Mucus-secreting cells	6485 NX
Rectum	10950 NX
Small intestine	5576 NX
Colon	2438 NX

Muller glia cells	1458 NX
Eye	1458 NX

Pancreatic endocrine cells	7817 NX
Pancreas	7817 NX

Paneth cells	5029 NX
Rectum	9332 NX
Small intestine	5029 NX
Colon	1549 NX

Peritubular cells	6781 NX
Testis	6781 NX

Proximal tubular cells	10372 NX
Kidney	10372 NX

Rod photoreceptor cells	952 NX
Eye	952 NX

Sertoli cells	3480 NX
Testis	3480 NX

Smooth muscle cells	5700 NX
Prostate	10828 NX
Skin	6902 NX
Pancreas	4665 NX
Heart muscle	278 NX

Spermatocytes	1276 NX
Testis	1276 NX

Spermatogonia	709 NX
Testis	709 NX

Suprabasal keratinocytes	8789 NX
Skin	8789 NX

Syncytiotrophoblasts	9272 NX
Placenta	9272 NX

T-cells	8651 NX
Prostate	9675 NX
Kidney	9034 NX
Skin	8651 NX
Liver	7810 NX
Lung	4072 NX
Colon	1558 NX

Undifferentiated cells	9250 NX
Small intestine	10871 NX
Rectum	9935 NX
Colon	1708 NX

Urothelial cells	10618 NX
Prostate	10618 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.