Cell type atlas - THYN1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

THYN1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	THYN1
Gene descriptionⁱ Full gene name according to HGNC.	Thymocyte nuclear protein 1
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	4

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	30 NX
Lung	30 NX

Alveolar cells type 2	30 NX
Lung	30 NX

B-cells	35 NX
Kidney	62 NX
Liver	35 NX
Colon	7 NX

Basal glandular cells	31 NX
Prostate	31 NX

Basal keratinocytes	21 NX
Skin	21 NX

Bipolar cells	28 NX
Eye	28 NX

Cardiomyocytes	48 NX
Heart muscle	48 NX

Cholangiocytes	46 NX
Liver	46 NX

Ciliated cells	58 NX
Lung	58 NX

Club cells	36 NX
Lung	36 NX

Collecting duct cells	35 NX
Kidney	35 NX

Cone photoreceptor cells	14 NX
Eye	14 NX

Cytotrophoblasts	49 NX
Placenta	49 NX

Distal tubular cells	73 NX
Kidney	73 NX

Ductal cells	42 NX
Pancreas	42 NX

Early spermatids	19 NX
Testis	19 NX

Endothelial cells	37 NX
Testis	57 NX
Placenta	55 NX
Liver	45 NX
Heart muscle	45 NX
Eye	39 NX
Skin	33 NX
Lung	26 NX
Pancreas	22 NX
Prostate	17 NX

Enterocytes	25 NX
Small intestine	40 NX
Rectum	28 NX
Colon	12 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	49 NX
Pancreas	49 NX

Extravillous trophoblasts	45 NX
Placenta	45 NX

Fibroblasts	39 NX
Heart muscle	53 NX
Placenta	44 NX
Skin	33 NX
Prostate	18 NX
Lung	16 NX

Glandular cells	16 NX
Prostate	16 NX

Granulocytes	39 NX
Lung	42 NX
Colon	37 NX

Hepatocytes	42 NX
Liver	42 NX

Hofbauer cells	46 NX
Placenta	46 NX

Horizontal cells	27 NX
Eye	27 NX

Intestinal endocrine cells	55 NX
Rectum	56 NX
Colon	54 NX

Ito cells	25 NX
Liver	25 NX

Kupffer cells	23 NX
Liver	23 NX

Late spermatids	14 NX
Testis	14 NX

Leydig cells	47 NX
Testis	47 NX

Macrophages	30 NX
Kidney	51 NX
Testis	35 NX
Pancreas	35 NX
Lung	30 NX
Prostate	25 NX
Skin	20 NX

Melanocytes	39 NX
Skin	39 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	41 NX
Pancreas	41 NX

Mucus-secreting cells	39 NX
Rectum	57 NX
Small intestine	38 NX
Colon	38 NX

Muller glia cells	43 NX
Eye	43 NX

Pancreatic endocrine cells	43 NX
Pancreas	43 NX

Paneth cells	32 NX
Rectum	53 NX
Small intestine	32 NX
Colon	6 NX

Peritubular cells	46 NX
Testis	46 NX

Proximal tubular cells	70 NX
Kidney	70 NX

Rod photoreceptor cells	18 NX
Eye	18 NX

Sertoli cells	45 NX
Testis	45 NX

Smooth muscle cells	32 NX
Heart muscle	77 NX
Pancreas	32 NX
Skin	31 NX
Prostate	27 NX

Spermatocytes	74 NX
Testis	74 NX

Spermatogonia	77 NX
Testis	77 NX

Suprabasal keratinocytes	18 NX
Skin	18 NX

Syncytiotrophoblasts	12 NX
Placenta	12 NX

T-cells	37 NX
Kidney	70 NX
Skin	42 NX
Lung	40 NX
Colon	30 NX
Liver	29 NX
Prostate	22 NX

Undifferentiated cells	53 NX
Small intestine	64 NX
Rectum	49 NX
Colon	38 NX

Urothelial cells	23 NX
Prostate	23 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.