Cell type atlas - FAU - The Human Protein Atlas

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FAU

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	FAU
Gene descriptionⁱ Full gene name according to HGNC.	FAU, ubiquitin like and ribosomal protein S30 fusion
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Plasma proteins Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	8

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	596 NX
Lung	596 NX

Alveolar cells type 2	952 NX
Lung	952 NX

B-cells	2941 NX
Kidney	3774 NX
Liver	2941 NX
Colon	1236 NX

Basal glandular cells	2547 NX
Prostate	2547 NX

Basal keratinocytes	3352 NX
Skin	3352 NX

Bipolar cells	328 NX
Eye	328 NX

Cardiomyocytes	461 NX
Heart muscle	461 NX

Cholangiocytes	1580 NX
Liver	1580 NX

Ciliated cells	746 NX
Lung	746 NX

Club cells	1040 NX
Lung	1040 NX

Collecting duct cells	909 NX
Kidney	909 NX

Cone photoreceptor cells	185 NX
Eye	185 NX

Cytotrophoblasts	1890 NX
Placenta	1890 NX

Distal tubular cells	1738 NX
Kidney	1738 NX

Ductal cells	1226 NX
Pancreas	1226 NX

Early spermatids	710 NX
Testis	710 NX

Endothelial cells	1573 NX
Skin	2680 NX
Prostate	2605 NX
Testis	1978 NX
Liver	1764 NX
Placenta	1573 NX
Pancreas	989 NX
Eye	950 NX
Lung	683 NX
Heart muscle	291 NX

Enterocytes	1664 NX
Small intestine	2088 NX
Colon	1439 NX
Rectum	1161 NX

Erythroid cells	1028 NX
Liver	1028 NX

Exocrine glandular cells	2338 NX
Pancreas	2338 NX

Extravillous trophoblasts	2188 NX
Placenta	2188 NX

Fibroblasts	1714 NX
Skin	1991 NX
Prostate	1836 NX
Placenta	1467 NX
Lung	1270 NX
Heart muscle	370 NX

Glandular cells	2189 NX
Prostate	2189 NX

Granulocytes	1307 NX
Lung	1769 NX
Colon	845 NX

Hepatocytes	1659 NX
Liver	1659 NX

Hofbauer cells	1928 NX
Placenta	1928 NX

Horizontal cells	180 NX
Eye	180 NX

Intestinal endocrine cells	1179 NX
Rectum	1482 NX
Colon	877 NX

Ito cells	1412 NX
Liver	1412 NX

Kupffer cells	2371 NX
Liver	2371 NX

Late spermatids	1490 NX
Testis	1490 NX

Leydig cells	2117 NX
Testis	2117 NX

Macrophages	2867 NX
Skin	3263 NX
Kidney	3199 NX
Prostate	2896 NX
Testis	2872 NX
Lung	1360 NX
Pancreas	1207 NX

Melanocytes	2014 NX
Skin	2014 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	2418 NX
Pancreas	2418 NX

Mucus-secreting cells	1788 NX
Rectum	2490 NX
Colon	1761 NX
Small intestine	1618 NX

Muller glia cells	429 NX
Eye	429 NX

Pancreatic endocrine cells	1806 NX
Pancreas	1806 NX

Paneth cells	2457 NX
Small intestine	2795 NX
Rectum	2457 NX
Colon	2004 NX

Peritubular cells	1156 NX
Testis	1156 NX

Proximal tubular cells	1845 NX
Kidney	1845 NX

Rod photoreceptor cells	362 NX
Eye	362 NX

Sertoli cells	1100 NX
Testis	1100 NX

Smooth muscle cells	2206 NX
Skin	2925 NX
Prostate	2206 NX
Pancreas	1274 NX
Heart muscle	380 NX

Spermatocytes	745 NX
Testis	745 NX

Spermatogonia	649 NX
Testis	649 NX

Suprabasal keratinocytes	3668 NX
Skin	3668 NX

Syncytiotrophoblasts	2336 NX
Placenta	2336 NX

T-cells	2034 NX
Skin	3580 NX
Kidney	3018 NX
Prostate	2916 NX
Liver	1930 NX
Lung	1423 NX
Colon	1052 NX

Undifferentiated cells	2040 NX
Rectum	2283 NX
Small intestine	2040 NX
Colon	1080 NX

Urothelial cells	2957 NX
Prostate	2957 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.