Cell type atlas - RPS3 - The Human Protein Atlas

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RPS3

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RPS3
Gene descriptionⁱ Full gene name according to HGNC.	Ribosomal protein S3
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Cancer-related genes Enzymes Plasma proteins Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	11

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	867 NX
Lung	867 NX

Alveolar cells type 2	1237 NX
Lung	1237 NX

B-cells	4968 NX
Kidney	5810 NX
Liver	4968 NX
Colon	1396 NX

Basal glandular cells	6163 NX
Prostate	6163 NX

Basal keratinocytes	5594 NX
Skin	5594 NX

Bipolar cells	395 NX
Eye	395 NX

Cardiomyocytes	376 NX
Heart muscle	376 NX

Cholangiocytes	1814 NX
Liver	1814 NX

Ciliated cells	684 NX
Lung	684 NX

Club cells	1733 NX
Lung	1733 NX

Collecting duct cells	689 NX
Kidney	689 NX

Cone photoreceptor cells	126 NX
Eye	126 NX

Cytotrophoblasts	5422 NX
Placenta	5422 NX

Distal tubular cells	1850 NX
Kidney	1850 NX

Ductal cells	2099 NX
Pancreas	2099 NX

Early spermatids	349 NX
Testis	349 NX

Endothelial cells	3203 NX
Prostate	5030 NX
Skin	4278 NX
Testis	3996 NX
Placenta	3971 NX
Liver	3203 NX
Pancreas	1873 NX
Eye	975 NX
Lung	925 NX
Heart muscle	330 NX

Enterocytes	1730 NX
Small intestine	2378 NX
Colon	1534 NX
Rectum	1439 NX

Erythroid cells	1308 NX
Liver	1308 NX

Exocrine glandular cells	4687 NX
Pancreas	4687 NX

Extravillous trophoblasts	7894 NX
Placenta	7894 NX

Fibroblasts	2767 NX
Placenta	3795 NX
Prostate	2767 NX
Skin	2657 NX
Lung	2347 NX
Heart muscle	381 NX

Glandular cells	3521 NX
Prostate	3521 NX

Granulocytes	1562 NX
Lung	2188 NX
Colon	937 NX

Hepatocytes	1179 NX
Liver	1179 NX

Hofbauer cells	3205 NX
Placenta	3205 NX

Horizontal cells	126 NX
Eye	126 NX

Intestinal endocrine cells	1989 NX
Rectum	2846 NX
Colon	1132 NX

Ito cells	2139 NX
Liver	2139 NX

Kupffer cells	2727 NX
Liver	2727 NX

Late spermatids	763 NX
Testis	763 NX

Leydig cells	3477 NX
Testis	3477 NX

Macrophages	3125 NX
Prostate	4932 NX
Skin	3754 NX
Testis	3678 NX
Kidney	3061 NX
Lung	1267 NX
Pancreas	1247 NX

Melanocytes	2689 NX
Skin	2689 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	3453 NX
Pancreas	3453 NX

Mucus-secreting cells	3996 NX
Rectum	5981 NX
Small intestine	3939 NX
Colon	2241 NX

Muller glia cells	368 NX
Eye	368 NX

Pancreatic endocrine cells	3770 NX
Pancreas	3770 NX

Paneth cells	2872 NX
Rectum	4907 NX
Small intestine	2872 NX
Colon	1845 NX

Peritubular cells	1695 NX
Testis	1695 NX

Proximal tubular cells	1678 NX
Kidney	1678 NX

Rod photoreceptor cells	343 NX
Eye	343 NX

Sertoli cells	1100 NX
Testis	1100 NX

Smooth muscle cells	3089 NX
Skin	3427 NX
Prostate	3160 NX
Pancreas	2815 NX
Heart muscle	352 NX

Spermatocytes	438 NX
Testis	438 NX

Spermatogonia	579 NX
Testis	579 NX

Suprabasal keratinocytes	6856 NX
Skin	6856 NX

Syncytiotrophoblasts	4907 NX
Placenta	4907 NX

T-cells	4548 NX
Kidney	6593 NX
Skin	5534 NX
Prostate	5221 NX
Liver	4180 NX
Lung	2260 NX
Colon	1297 NX

Undifferentiated cells	5853 NX
Small intestine	7319 NX
Rectum	5853 NX
Colon	1639 NX

Urothelial cells	6063 NX
Prostate	6063 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.