Cell type atlas - GSTO1 - The Human Protein Atlas

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GSTO1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	GSTO1
Gene descriptionⁱ Full gene name according to HGNC.	Glutathione S-transferase omega 1
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Enzymes Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	5

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (SK-MEL-30)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	72 NX
Lung	72 NX

Alveolar cells type 2	58 NX
Lung	58 NX

B-cells	99 NX
Colon	111 NX
Kidney	107 NX
Liver	80 NX

Basal glandular cells	286 NX
Prostate	286 NX

Basal keratinocytes	83 NX
Skin	83 NX

Bipolar cells	26 NX
Eye	26 NX

Cardiomyocytes	290 NX
Heart muscle	290 NX

Cholangiocytes	245 NX
Liver	245 NX

Ciliated cells	59 NX
Lung	59 NX

Club cells	79 NX
Lung	79 NX

Collecting duct cells	96 NX
Kidney	96 NX

Cone photoreceptor cells	20 NX
Eye	20 NX

Cytotrophoblasts	399 NX
Placenta	399 NX

Distal tubular cells	282 NX
Kidney	282 NX

Ductal cells	289 NX
Pancreas	289 NX

Early spermatids	14 NX
Testis	14 NX

Endothelial cells	119 NX
Pancreas	501 NX
Prostate	278 NX
Placenta	201 NX
Liver	196 NX
Lung	120 NX
Testis	116 NX
Heart muscle	104 NX
Skin	100 NX
Eye	81 NX

Enterocytes	130 NX
Small intestine	383 NX
Colon	106 NX
Rectum	64 NX

Erythroid cells	70 NX
Liver	70 NX

Exocrine glandular cells	216 NX
Pancreas	216 NX

Extravillous trophoblasts	136 NX
Placenta	136 NX

Fibroblasts	155 NX
Prostate	599 NX
Placenta	189 NX
Heart muscle	176 NX
Skin	95 NX
Lung	82 NX

Glandular cells	94 NX
Prostate	94 NX

Granulocytes	142 NX
Lung	147 NX
Colon	138 NX

Hepatocytes	612 NX
Liver	612 NX

Hofbauer cells	643 NX
Placenta	643 NX

Horizontal cells	22 NX
Eye	22 NX

Intestinal endocrine cells	99 NX
Colon	112 NX
Rectum	87 NX

Ito cells	339 NX
Liver	339 NX

Kupffer cells	323 NX
Liver	323 NX

Late spermatids	12 NX
Testis	12 NX

Leydig cells	106 NX
Testis	106 NX

Macrophages	398 NX
Pancreas	1196 NX
Prostate	537 NX
Kidney	489 NX
Lung	487 NX
Testis	243 NX
Skin	184 NX

Melanocytes	120 NX
Skin	120 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	265 NX
Pancreas	265 NX

Mucus-secreting cells	130 NX
Small intestine	191 NX
Colon	155 NX
Rectum	103 NX

Muller glia cells	50 NX
Eye	50 NX

Pancreatic endocrine cells	258 NX
Pancreas	258 NX

Paneth cells	118 NX
Small intestine	193 NX
Rectum	118 NX
Colon	101 NX

Peritubular cells	106 NX
Testis	106 NX

Proximal tubular cells	411 NX
Kidney	411 NX

Rod photoreceptor cells	25 NX
Eye	25 NX

Sertoli cells	149 NX
Testis	149 NX

Smooth muscle cells	124 NX
Pancreas	702 NX
Prostate	239 NX
Heart muscle	124 NX
Skin	81 NX

Spermatocytes	5 NX
Testis	5 NX

Spermatogonia	3 NX
Testis	3 NX

Suprabasal keratinocytes	69 NX
Skin	69 NX

Syncytiotrophoblasts	93 NX
Placenta	93 NX

T-cells	101 NX
Prostate	140 NX
Kidney	117 NX
Skin	104 NX
Liver	99 NX
Colon	85 NX
Lung	68 NX

Undifferentiated cells	167 NX
Small intestine	238 NX
Colon	179 NX
Rectum	112 NX

Urothelial cells	177 NX
Prostate	177 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.