Cell type atlas - SNRNP200 - The Human Protein Atlas

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SNRNP200

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	SNRNP200
Gene descriptionⁱ Full gene name according to HGNC.	Small nuclear ribonucleoprotein U5 subunit 200
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Disease related genes Enzymes Plasma proteins Potential drug targets
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	1

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	42 NX
Lung	42 NX

Alveolar cells type 2	52 NX
Lung	52 NX

B-cells	50 NX
Colon	75 NX
Liver	50 NX
Kidney	27 NX

Basal glandular cells	24 NX
Prostate	24 NX

Basal keratinocytes	26 NX
Skin	26 NX

Bipolar cells	74 NX
Eye	74 NX

Cardiomyocytes	31 NX
Heart muscle	31 NX

Cholangiocytes	71 NX
Liver	71 NX

Ciliated cells	40 NX
Lung	40 NX

Club cells	46 NX
Lung	46 NX

Collecting duct cells	49 NX
Kidney	49 NX

Cone photoreceptor cells	98 NX
Eye	98 NX

Cytotrophoblasts	36 NX
Placenta	36 NX

Distal tubular cells	5 NX
Kidney	5 NX

Ductal cells	36 NX
Pancreas	36 NX

Early spermatids	23 NX
Testis	22 NX

Endothelial cells	42 NX
Lung	55 NX
Heart muscle	50 NX
Testis	49 NX
Placenta	45 NX
Pancreas	43 NX
Eye	37 NX
Liver	36 NX
Skin	30 NX
Prostate	28 NX

Enterocytes	38 NX
Small intestine	40 NX
Colon	37 NX
Rectum	37 NX

Erythroid cells	23 NX
Liver	23 NX

Exocrine glandular cells	40 NX
Pancreas	40 NX

Extravillous trophoblasts	31 NX
Placenta	31 NX

Fibroblasts	31 NX
Lung	44 NX
Placenta	34 NX
Heart muscle	31 NX
Skin	29 NX
Prostate	19 NX

Glandular cells	30 NX
Prostate	30 NX

Granulocytes	24 NX
Lung	30 NX
Colon	18 NX

Hepatocytes	43 NX
Liver	43 NX

Hofbauer cells	31 NX
Placenta	31 NX

Horizontal cells	83 NX
Eye	83 NX

Intestinal endocrine cells	45 NX
Colon	48 NX
Rectum	42 NX

Ito cells	33 NX
Liver	33 NX

Kupffer cells	28 NX
Liver	28 NX

Late spermatids	11 NX
Testis	11 NX

Leydig cells	53 NX
Testis	53 NX

Macrophages	32 NX
Lung	47 NX
Testis	40 NX
Skin	32 NX
Kidney	28 NX
Prostate	25 NX
Pancreas	21 NX

Melanocytes	17 NX
Skin	17 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	38 NX
Pancreas	38 NX

Mucus-secreting cells	41 NX
Small intestine	42 NX
Rectum	40 NX
Colon	28 NX

Muller glia cells	92 NX
Eye	92 NX

Pancreatic endocrine cells	36 NX
Pancreas	36 NX

Paneth cells	35 NX
Rectum	37 NX
Small intestine	35 NX
Colon	12 NX

Peritubular cells	52 NX
Testis	52 NX

Proximal tubular cells	15 NX
Kidney	15 NX

Rod photoreceptor cells	129 NX
Eye	129 NX

Sertoli cells	65 NX
Testis	65 NX

Smooth muscle cells	39 NX
Heart muscle	55 NX
Skin	40 NX
Pancreas	25 NX
Prostate	20 NX

Spermatocytes	87 NX
Testis	87 NX

Spermatogonia	55 NX
Testis	55 NX

Suprabasal keratinocytes	29 NX
Skin	29 NX

Syncytiotrophoblasts	37 NX
Placenta	37 NX

T-cells	66 NX
Lung	85 NX
Skin	70 NX
Liver	66 NX
Colon	53 NX
Prostate	35 NX
Kidney	34 NX

Undifferentiated cells	41 NX
Small intestine	49 NX
Rectum	41 NX
Colon	41 NX

Urothelial cells	27 NX
Prostate	27 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.