Cell type atlas - ACP1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

ACP1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	ACP1
Gene descriptionⁱ Full gene name according to HGNC.	Acid phosphatase 1
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Enzymes Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	5

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Group enriched (Late spermatids, Early spermatids)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Group enriched (Late spermatids, Early spermatids)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	42 NX
Lung	42 NX

Alveolar cells type 2	89 NX
Lung	88 NX

B-cells	101 NX
Liver	130 NX
Colon	114 NX
Kidney	89 NX

Basal glandular cells	80 NX
Prostate	80 NX

Basal keratinocytes	70 NX
Skin	70 NX

Bipolar cells	51 NX
Eye	51 NX

Cardiomyocytes	74 NX
Heart muscle	74 NX

Cholangiocytes	110 NX
Liver	110 NX

Ciliated cells	130 NX
Lung	130 NX

Club cells	67 NX
Lung	67 NX

Collecting duct cells	65 NX
Kidney	65 NX

Cone photoreceptor cells	8 NX
Eye	8 NX

Cytotrophoblasts	180 NX
Placenta	180 NX

Distal tubular cells	229 NX
Kidney	229 NX

Ductal cells	194 NX
Pancreas	194 NX

Early spermatids	914 NX
Testis	914 NX

Endothelial cells	65 NX
Pancreas	122 NX
Placenta	86 NX
Prostate	82 NX
Testis	81 NX
Skin	69 NX
Heart muscle	61 NX
Liver	54 NX
Lung	50 NX
Eye	49 NX

Enterocytes	85 NX
Small intestine	146 NX
Rectum	80 NX
Colon	57 NX

Erythroid cells	164 NX
Liver	164 NX

Exocrine glandular cells	147 NX
Pancreas	147 NX

Extravillous trophoblasts	235 NX
Placenta	235 NX

Fibroblasts	72 NX
Placenta	111 NX
Lung	80 NX
Prostate	71 NX
Heart muscle	70 NX
Skin	64 NX

Glandular cells	111 NX
Prostate	111 NX

Granulocytes	68 NX
Lung	72 NX
Colon	64 NX

Hepatocytes	112 NX
Liver	112 NX

Hofbauer cells	124 NX
Placenta	124 NX

Horizontal cells	27 NX
Eye	27 NX

Intestinal endocrine cells	79 NX
Colon	95 NX
Rectum	63 NX

Ito cells	50 NX
Liver	50 NX

Kupffer cells	58 NX
Liver	58 NX

Late spermatids	1667 NX
Testis	1667 NX

Leydig cells	88 NX
Testis	88 NX

Macrophages	75 NX
Pancreas	119 NX
Kidney	81 NX
Testis	77 NX
Prostate	73 NX
Skin	68 NX
Lung	66 NX

Melanocytes	78 NX
Skin	78 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	116 NX
Pancreas	116 NX

Mucus-secreting cells	108 NX
Colon	127 NX
Rectum	104 NX
Small intestine	101 NX

Muller glia cells	65 NX
Eye	65 NX

Pancreatic endocrine cells	156 NX
Pancreas	155 NX

Paneth cells	109 NX
Rectum	114 NX
Small intestine	109 NX
Colon	75 NX

Peritubular cells	87 NX
Testis	87 NX

Proximal tubular cells	242 NX
Kidney	242 NX

Rod photoreceptor cells	44 NX
Eye	44 NX

Sertoli cells	91 NX
Testis	91 NX

Smooth muscle cells	79 NX
Pancreas	169 NX
Heart muscle	82 NX
Prostate	79 NX
Skin	64 NX

Spermatocytes	112 NX
Testis	112 NX

Spermatogonia	122 NX
Testis	122 NX

Suprabasal keratinocytes	80 NX
Skin	80 NX

Syncytiotrophoblasts	157 NX
Placenta	157 NX

T-cells	94 NX
Kidney	119 NX
Colon	104 NX
Liver	95 NX
Lung	92 NX
Skin	80 NX
Prostate	57 NX

Undifferentiated cells	114 NX
Small intestine	152 NX
Colon	133 NX
Rectum	112 NX

Urothelial cells	108 NX
Prostate	108 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.