Cell type atlas - RAB13 - The Human Protein Atlas

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RAB13

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RAB13
Gene descriptionⁱ Full gene name according to HGNC.	RAB13, member RAS oncogene family
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Group enriched (plasmacytoid DC, myeloid DC, classical monocyte)
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in some
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (ASC TERT1)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	39 NX
Lung	39 NX

Alveolar cells type 2	71 NX
Lung	71 NX

B-cells	13 NX
Liver	19 NX
Kidney	13 NX
Colon	13 NX

Basal glandular cells	149 NX
Prostate	149 NX

Basal keratinocytes	82 NX
Skin	82 NX

Bipolar cells	1 NX
Eye	1 NX

Cardiomyocytes	69 NX
Heart muscle	69 NX

Cholangiocytes	104 NX
Liver	104 NX

Ciliated cells	56 NX
Lung	56 NX

Club cells	64 NX
Lung	64 NX

Collecting duct cells	103 NX
Kidney	103 NX

Cone photoreceptor cells	2 NX
Eye	2 NX

Cytotrophoblasts	102 NX
Placenta	102 NX

Distal tubular cells	114 NX
Kidney	114 NX

Ductal cells	188 NX
Pancreas	188 NX

Early spermatids	87 NX
Testis	87 NX

Endothelial cells	181 NX
Prostate	479 NX
Placenta	288 NX
Testis	282 NX
Pancreas	236 NX
Liver	184 NX
Skin	153 NX
Lung	108 NX
Eye	86 NX
Heart muscle	69 NX

Enterocytes	76 NX
Small intestine	111 NX
Colon	74 NX
Rectum	66 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	131 NX
Pancreas	131 NX

Extravillous trophoblasts	138 NX
Placenta	138 NX

Fibroblasts	110 NX
Prostate	155 NX
Placenta	147 NX
Lung	95 NX
Skin	89 NX
Heart muscle	63 NX

Glandular cells	182 NX
Prostate	182 NX

Granulocytes	40 NX
Colon	55 NX
Lung	26 NX

Hepatocytes	126 NX
Liver	126 NX

Hofbauer cells	237 NX
Placenta	237 NX

Horizontal cells	0 NX
Eye	0 NX

Intestinal endocrine cells	86 NX
Colon	99 NX
Rectum	73 NX

Ito cells	141 NX
Liver	141 NX

Kupffer cells	102 NX
Liver	102 NX

Late spermatids	185 NX
Testis	185 NX

Leydig cells	98 NX
Testis	98 NX

Macrophages	113 NX
Pancreas	402 NX
Testis	159 NX
Prostate	130 NX
Lung	102 NX
Skin	89 NX
Kidney	83 NX

Melanocytes	95 NX
Skin	95 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	413 NX
Pancreas	413 NX

Mucus-secreting cells	147 NX
Colon	191 NX
Small intestine	170 NX
Rectum	133 NX

Muller glia cells	17 NX
Eye	17 NX

Pancreatic endocrine cells	150 NX
Pancreas	150 NX

Paneth cells	95 NX
Rectum	110 NX
Small intestine	95 NX
Colon	95 NX

Peritubular cells	117 NX
Testis	117 NX

Proximal tubular cells	162 NX
Kidney	162 NX

Rod photoreceptor cells	3 NX
Eye	3 NX

Sertoli cells	149 NX
Testis	149 NX

Smooth muscle cells	190 NX
Prostate	248 NX
Pancreas	195 NX
Skin	156 NX
Heart muscle	82 NX

Spermatocytes	61 NX
Testis	61 NX

Spermatogonia	17 NX
Testis	17 NX

Suprabasal keratinocytes	86 NX
Skin	86 NX

Syncytiotrophoblasts	78 NX
Placenta	78 NX

T-cells	13 NX
Prostate	31 NX
Kidney	14 NX
Skin	13 NX
Liver	10 NX
Lung	7 NX
Colon	3 NX

Undifferentiated cells	131 NX
Colon	140 NX
Small intestine	132 NX
Rectum	129 NX

Urothelial cells	174 NX
Prostate	174 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.