Cell type atlas - CTTNBP2NL - The Human Protein Atlas

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CTTNBP2NL

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	CTTNBP2NL
Gene descriptionⁱ Full gene name according to HGNC.	CTTNBP2 N-terminal like
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (myeloid DC)
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in some
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (TIME)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	54 NX
Lung	54 NX

Alveolar cells type 2	19 NX
Lung	19 NX

B-cells	8 NX
Kidney	9 NX
Liver	8 NX
Colon	7 NX

Basal glandular cells	19 NX
Prostate	19 NX

Basal keratinocytes	35 NX
Skin	35 NX

Bipolar cells	10 NX
Eye	10 NX

Cardiomyocytes	8 NX
Heart muscle	8 NX

Cholangiocytes	5 NX
Liver	5 NX

Ciliated cells	15 NX
Lung	15 NX

Club cells	44 NX
Lung	44 NX

Collecting duct cells	21 NX
Kidney	21 NX

Cone photoreceptor cells	6 NX
Eye	6 NX

Cytotrophoblasts	14 NX
Placenta	14 NX

Distal tubular cells	3 NX
Kidney	3 NX

Ductal cells	30 NX
Pancreas	30 NX

Early spermatids	2 NX
Testis	2 NX

Endothelial cells	61 NX
Heart muscle	155 NX
Prostate	104 NX
Lung	88 NX
Skin	62 NX
Testis	61 NX
Eye	59 NX
Pancreas	54 NX
Liver	41 NX
Placenta	29 NX

Enterocytes	31 NX
Colon	70 NX
Rectum	41 NX
Small intestine	18 NX

Erythroid cells	23 NX
Liver	23 NX

Exocrine glandular cells	19 NX
Pancreas	19 NX

Extravillous trophoblasts	11 NX
Placenta	11 NX

Fibroblasts	17 NX
Heart muscle	70 NX
Prostate	23 NX
Lung	21 NX
Skin	19 NX
Placenta	9 NX

Glandular cells	23 NX
Prostate	23 NX

Granulocytes	19 NX
Lung	19 NX
Colon	18 NX

Hepatocytes	1 NX
Liver	1 NX

Hofbauer cells	12 NX
Placenta	12 NX

Horizontal cells	5 NX
Eye	5 NX

Intestinal endocrine cells	8 NX
Colon	14 NX
Rectum	2 NX

Ito cells	35 NX
Liver	35 NX

Kupffer cells	24 NX
Liver	24 NX

Late spermatids	2 NX
Testis	2 NX

Leydig cells	10 NX
Testis	10 NX

Macrophages	41 NX
Testis	89 NX
Skin	86 NX
Prostate	83 NX
Lung	28 NX
Pancreas	16 NX
Kidney	13 NX

Melanocytes	15 NX
Skin	15 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	45 NX
Pancreas	45 NX

Mucus-secreting cells	23 NX
Colon	28 NX
Small intestine	27 NX
Rectum	16 NX

Muller glia cells	11 NX
Eye	11 NX

Pancreatic endocrine cells	37 NX
Pancreas	37 NX

Paneth cells	32 NX
Colon	83 NX
Small intestine	32 NX
Rectum	26 NX

Peritubular cells	11 NX
Testis	11 NX

Proximal tubular cells	17 NX
Kidney	17 NX

Rod photoreceptor cells	9 NX
Eye	9 NX

Sertoli cells	19 NX
Testis	19 NX

Smooth muscle cells	15 NX
Heart muscle	78 NX
Prostate	15 NX
Skin	14 NX
Pancreas	14 NX

Spermatocytes	14 NX
Testis	14 NX

Spermatogonia	15 NX
Testis	15 NX

Suprabasal keratinocytes	53 NX
Skin	53 NX

Syncytiotrophoblasts	21 NX
Placenta	21 NX

T-cells	1 NX
Skin	11 NX
Lung	4 NX
Kidney	3 NX
Colon	3 NX
Prostate	0 NX
Liver	0 NX

Undifferentiated cells	17 NX
Colon	22 NX
Rectum	21 NX
Small intestine	16 NX

Urothelial cells	52 NX
Prostate	52 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.