Cell type atlas - RPL11 - The Human Protein Atlas

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RPL11

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RPL11
Gene descriptionⁱ Full gene name according to HGNC.	Ribosomal protein L11
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Disease related genes Plasma proteins Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	3

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	1096 NX
Lung	1096 NX

Alveolar cells type 2	1949 NX
Lung	1949 NX

B-cells	5841 NX
Kidney	7606 NX
Liver	5840 NX
Colon	1499 NX

Basal glandular cells	6305 NX
Prostate	6305 NX

Basal keratinocytes	5888 NX
Skin	5888 NX

Bipolar cells	338 NX
Eye	338 NX

Cardiomyocytes	523 NX
Heart muscle	523 NX

Cholangiocytes	3004 NX
Liver	3004 NX

Ciliated cells	1172 NX
Lung	1172 NX

Club cells	1937 NX
Lung	1937 NX

Collecting duct cells	1068 NX
Kidney	1068 NX

Cone photoreceptor cells	145 NX
Eye	145 NX

Cytotrophoblasts	4113 NX
Placenta	4113 NX

Distal tubular cells	4074 NX
Kidney	4074 NX

Ductal cells	2275 NX
Pancreas	2275 NX

Early spermatids	832 NX
Testis	832 NX

Endothelial cells	3353 NX
Skin	5073 NX
Prostate	4797 NX
Testis	4205 NX
Liver	3423 NX
Placenta	3353 NX
Pancreas	1905 NX
Lung	1272 NX
Eye	1157 NX
Heart muscle	382 NX

Enterocytes	1874 NX
Small intestine	3605 NX
Colon	1616 NX
Rectum	1454 NX

Erythroid cells	1261 NX
Liver	1261 NX

Exocrine glandular cells	5802 NX
Pancreas	5802 NX

Extravillous trophoblasts	6646 NX
Placenta	6646 NX

Fibroblasts	3301 NX
Skin	3781 NX
Placenta	3218 NX
Lung	2782 NX
Prostate	2643 NX
Heart muscle	454 NX

Glandular cells	4732 NX
Prostate	4732 NX

Granulocytes	1988 NX
Lung	3011 NX
Colon	964 NX

Hepatocytes	2713 NX
Liver	2713 NX

Hofbauer cells	3408 NX
Placenta	3408 NX

Horizontal cells	196 NX
Eye	196 NX

Intestinal endocrine cells	2080 NX
Rectum	3022 NX
Colon	1138 NX

Ito cells	2712 NX
Liver	2712 NX

Kupffer cells	3936 NX
Liver	3936 NX

Late spermatids	1677 NX
Testis	1677 NX

Leydig cells	4262 NX
Testis	4262 NX

Macrophages	5100 NX
Prostate	6034 NX
Skin	6032 NX
Kidney	5164 NX
Testis	5036 NX
Lung	2156 NX
Pancreas	1640 NX

Melanocytes	3565 NX
Skin	3565 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	4184 NX
Pancreas	4184 NX

Mucus-secreting cells	3270 NX
Rectum	5072 NX
Small intestine	3243 NX
Colon	2259 NX

Muller glia cells	600 NX
Eye	600 NX

Pancreatic endocrine cells	3953 NX
Pancreas	3953 NX

Paneth cells	3416 NX
Rectum	4341 NX
Small intestine	3416 NX
Colon	1989 NX

Peritubular cells	1958 NX
Testis	1958 NX

Proximal tubular cells	3600 NX
Kidney	3600 NX

Rod photoreceptor cells	475 NX
Eye	475 NX

Sertoli cells	1391 NX
Testis	1391 NX

Smooth muscle cells	3247 NX
Skin	3972 NX
Prostate	3247 NX
Pancreas	2566 NX
Heart muscle	313 NX

Spermatocytes	515 NX
Testis	515 NX

Spermatogonia	526 NX
Testis	526 NX

Suprabasal keratinocytes	6987 NX
Skin	6987 NX

Syncytiotrophoblasts	3890 NX
Placenta	3890 NX

T-cells	3666 NX
Skin	6822 NX
Kidney	6014 NX
Prostate	5117 NX
Liver	3262 NX
Lung	2548 NX
Colon	1226 NX

Undifferentiated cells	4665 NX
Small intestine	5180 NX
Rectum	4941 NX
Colon	1553 NX

Urothelial cells	6181 NX
Prostate	6181 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.