Tissue expression of NFIC - Primary data - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

Search result

Field

Pathway

HELP

NEWS

NFIC

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

ANTIBODY PRIMARY DATAⁱ

Antibodies in assayⁱ

HPA052625 , CAB004300 , CAB004674

Tissue presentation order

Organ

Cell type

Alphabetical

Tissue			Antibody stainingⁱ This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation. Read more			Annotated protein expressionⁱ This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation. Read more
			HPA052625	CAB004300	CAB004674
			h m l n	h m l n	h m l n	h m l n
Brain
	Cerebral cortex	Neuronal cells
	Cerebral cortex	Endothelial cells
	Cerebral cortex	Glial cells
	Cerebral cortex	Neuropil
	Hippocampus	Neuronal cells
	Hippocampus	Glial cells
	Caudate	Neuronal cells
	Caudate	Glial cells
	Cerebellum	Purkinje cells
	Cerebellum	Cells in granular layer
	Cerebellum	Cells in molecular layer
Endocrine tissues
	Thyroid gland	Glandular cells
	Parathyroid gland	Glandular cells			N/A
	Adrenal gland	Glandular cells
Respiratory system
	Nasopharynx	Respiratory epithelial cells
	Bronchus	Respiratory epithelial cells
	Lung	Alveolar cells
	Lung	Macrophages
Proximal digestive tract
	Oral mucosa	Squamous epithelial cells
	Salivary gland	Glandular cells
	Esophagus	Squamous epithelial cells
Gastrointestinal tract
	Stomach 1	Glandular cells
	Stomach 2	Glandular cells
	Duodenum	Glandular cells
	Small intestine	Glandular cells
	Colon	Endothelial cells
	Colon	Glandular cells
	Colon	Peripheral nerve/ganglion		N/A
	Rectum	Glandular cells
Liver & gallbladder
	Liver	Hepatocytes
	Liver	Cholangiocytes
	Gallbladder	Glandular cells
Pancreas
	Pancreas	Exocrine glandular cells
	Pancreas	Pancreatic endocrine cells
Kidney & urinary bladder
	Kidney	Cells in glomeruli
	Kidney	Cells in tubules
	Urinary bladder	Urothelial cells
Male reproductive system
	Testis	Cells in seminiferous ducts	N/A
	Testis	Elongated or late spermatids		N/A	N/A
	Testis	Leydig cells
	Testis	Pachytene spermatocytes		N/A	N/A
	Testis	Peritubular cells		N/A	N/A
	Testis	Preleptotene spermatocytes		N/A	N/A
	Testis	Round or early spermatids		N/A	N/A
	Testis	Sertoli cells		N/A	N/A
	Testis	Spermatogonia cells		N/A	N/A
	Epididymis	Glandular cells
	Prostate	Glandular cells
	Seminal vesicle	Glandular cells
Breast and female reproductive system
	Breast	Adipocytes
	Breast	Glandular cells
	Breast	Myoepithelial cells
	Vagina	Squamous epithelial cells
	Cervix, uterine	Squamous epithelial cells
	Cervix, uterine	Glandular cells
	Endometrium 1	Glandular cells
	Endometrium 1	Cells in endometrial stroma
	Endometrium 2	Glandular cells
	Endometrium 2	Cells in endometrial stroma			N/A
	Fallopian tube	Glandular cells
	Ovary	Follicle cells	N/A		N/A
	Ovary	Ovarian stroma cells
	Placenta	Trophoblastic cells
	Placenta	Decidual cells			N/A
Muscle tissues
	Heart muscle	Cardiomyocytes
	Skeletal muscle	Myocytes
	Smooth muscle	Smooth muscle cells
Adipose & soft tissue
	Adipose tissue	Adipocytes
	Soft tissue 1	Peripheral nerve			N/A
	Soft tissue 1	Chondrocytes		N/A	N/A
	Soft tissue 1	Fibroblasts			N/A
	Soft tissue 2	Fibroblasts
	Soft tissue 2	Chondrocytes	N/A	N/A	N/A
	Soft tissue 2	Peripheral nerve
Skin
	Skin 1	Fibroblasts			N/A
	Skin 1	Keratinocytes			N/A
	Skin 1	Langerhans			N/A
	Skin 1	Melanocytes			N/A
	Skin 2	Epidermal cells
Bone marrow & lymphoid tissues
	Appendix	Glandular cells
	Appendix	Lymphoid tissue		N/A
	Bone marrow	Hematopoietic cells
	Lymph node	Germinal center cells
	Lymph node	Non-germinal center cells
	Tonsil	Germinal center cells
	Tonsil	Non-germinal center cells
	Tonsil	Squamous epithelial cells
	Spleen	Cells in white pulp			N/A
	Spleen	Cells in red pulp

Staining summaryⁱ

HPA052625	Most normal tissues displayed moderate nuclear positivity. Airways epithelium, testis, upper stomach, gall bladder, exocrine glandular cells, adrenal, renal tubules and squamous epithelium showed strong positivity. Trophoblastic cells, urothelial cells and small intestine were weakly stained or negative.
CAB004300	Decidual cells in placenta, hematopoietic cells, salivary glands, fallopian tube and respiratory epithelia showed moderate nuclear positivity. Myocytes displayed both cytoplasmic and nuclear immunoreactivity. Remaining normal cells were weakly stained or negative.
CAB004674	Most normal tissues displayed distinct nuclear staining. Strongest positivity was observed in glial cells and exocrine glandular cells. Basal layers in squamous epithelia stained stronger than the superficial layers.

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.