Cell type atlas - GALNT1 - The Human Protein Atlas

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GALNT1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	GALNT1
Gene descriptionⁱ Full gene name according to HGNC.	Polypeptide N-acetylgalactosaminyltransferase 1
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Enzymes Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular,Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	3

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (HUVEC TERT2)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	75 NX
Lung	75 NX

Alveolar cells type 2	36 NX
Lung	36 NX

B-cells	28 NX
Colon	37 NX
Liver	29 NX
Kidney	18 NX

Basal glandular cells	22 NX
Prostate	22 NX

Basal keratinocytes	27 NX
Skin	27 NX

Bipolar cells	30 NX
Eye	30 NX

Cardiomyocytes	34 NX
Heart muscle	34 NX

Cholangiocytes	54 NX
Liver	54 NX

Ciliated cells	32 NX
Lung	32 NX

Club cells	39 NX
Lung	39 NX

Collecting duct cells	16 NX
Kidney	16 NX

Cone photoreceptor cells	12 NX
Eye	12 NX

Cytotrophoblasts	24 NX
Placenta	24 NX

Distal tubular cells	7 NX
Kidney	7 NX

Ductal cells	35 NX
Pancreas	35 NX

Early spermatids	1 NX
Testis	1 NX

Endothelial cells	29 NX
Lung	53 NX
Skin	45 NX
Prostate	31 NX
Placenta	30 NX
Eye	30 NX
Pancreas	29 NX
Liver	29 NX
Heart muscle	26 NX
Testis	12 NX

Enterocytes	87 NX
Rectum	122 NX
Colon	91 NX
Small intestine	77 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	34 NX
Pancreas	34 NX

Extravillous trophoblasts	80 NX
Placenta	80 NX

Fibroblasts	44 NX
Placenta	86 NX
Lung	66 NX
Heart muscle	32 NX
Skin	30 NX
Prostate	24 NX

Glandular cells	56 NX
Prostate	56 NX

Granulocytes	20 NX
Lung	21 NX
Colon	18 NX

Hepatocytes	61 NX
Liver	61 NX

Hofbauer cells	64 NX
Placenta	64 NX

Horizontal cells	81 NX
Eye	81 NX

Intestinal endocrine cells	37 NX
Colon	37 NX
Rectum	37 NX

Ito cells	37 NX
Liver	37 NX

Kupffer cells	53 NX
Liver	53 NX

Late spermatids	2 NX
Testis	1 NX

Leydig cells	18 NX
Testis	18 NX

Macrophages	40 NX
Lung	54 NX
Prostate	43 NX
Kidney	43 NX
Pancreas	40 NX
Skin	29 NX
Testis	26 NX

Melanocytes	19 NX
Skin	19 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	14 NX
Pancreas	14 NX

Mucus-secreting cells	54 NX
Small intestine	71 NX
Rectum	57 NX
Colon	28 NX

Muller glia cells	102 NX
Eye	102 NX

Pancreatic endocrine cells	42 NX
Pancreas	42 NX

Paneth cells	49 NX
Rectum	62 NX
Colon	49 NX
Small intestine	28 NX

Peritubular cells	17 NX
Testis	17 NX

Proximal tubular cells	18 NX
Kidney	18 NX

Rod photoreceptor cells	24 NX
Eye	24 NX

Sertoli cells	13 NX
Testis	13 NX

Smooth muscle cells	22 NX
Heart muscle	27 NX
Pancreas	24 NX
Prostate	22 NX
Skin	17 NX

Spermatocytes	4 NX
Testis	4 NX

Spermatogonia	14 NX
Testis	14 NX

Suprabasal keratinocytes	72 NX
Skin	72 NX

Syncytiotrophoblasts	28 NX
Placenta	28 NX

T-cells	22 NX
Colon	55 NX
Kidney	29 NX
Skin	22 NX
Liver	21 NX
Prostate	18 NX
Lung	17 NX

Undifferentiated cells	70 NX
Small intestine	83 NX
Rectum	67 NX
Colon	50 NX

Urothelial cells	40 NX
Prostate	40 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.