Cell type atlas - NDUFB10 - The Human Protein Atlas

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NDUFB10

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	NDUFB10
Gene descriptionⁱ Full gene name according to HGNC.	NADH:ubiquinone oxidoreductase subunit B10
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	4

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Cardiomyocytes)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Cardiomyocytes)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	107 NX
Lung	107 NX

Alveolar cells type 2	72 NX
Lung	72 NX

B-cells	132 NX
Liver	227 NX
Kidney	152 NX
Colon	109 NX

Basal glandular cells	132 NX
Prostate	132 NX

Basal keratinocytes	152 NX
Skin	152 NX

Bipolar cells	82 NX
Eye	82 NX

Cardiomyocytes	1107 NX
Heart muscle	1107 NX

Cholangiocytes	301 NX
Liver	301 NX

Ciliated cells	161 NX
Lung	161 NX

Club cells	76 NX
Lung	76 NX

Collecting duct cells	208 NX
Kidney	208 NX

Cone photoreceptor cells	18 NX
Eye	18 NX

Cytotrophoblasts	314 NX
Placenta	313 NX

Distal tubular cells	832 NX
Kidney	832 NX

Ductal cells	248 NX
Pancreas	248 NX

Early spermatids	262 NX
Testis	262 NX

Endothelial cells	176 NX
Heart muscle	295 NX
Placenta	216 NX
Skin	194 NX
Pancreas	176 NX
Testis	152 NX
Liver	146 NX
Eye	132 NX
Prostate	106 NX
Lung	105 NX

Enterocytes	627 NX
Small intestine	729 NX
Colon	627 NX
Rectum	400 NX

Erythroid cells	164 NX
Liver	164 NX

Exocrine glandular cells	362 NX
Pancreas	362 NX

Extravillous trophoblasts	265 NX
Placenta	265 NX

Fibroblasts	185 NX
Heart muscle	454 NX
Placenta	227 NX
Skin	165 NX
Prostate	86 NX
Lung	78 NX

Glandular cells	120 NX
Prostate	120 NX

Granulocytes	111 NX
Colon	156 NX
Lung	65 NX

Hepatocytes	343 NX
Liver	343 NX

Hofbauer cells	280 NX
Placenta	280 NX

Horizontal cells	75 NX
Eye	75 NX

Intestinal endocrine cells	196 NX
Rectum	201 NX
Colon	190 NX

Ito cells	150 NX
Liver	150 NX

Kupffer cells	199 NX
Liver	199 NX

Late spermatids	687 NX
Testis	687 NX

Leydig cells	146 NX
Testis	146 NX

Macrophages	164 NX
Pancreas	260 NX
Kidney	238 NX
Skin	172 NX
Testis	161 NX
Prostate	136 NX
Lung	110 NX

Melanocytes	263 NX
Skin	263 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	257 NX
Pancreas	257 NX

Mucus-secreting cells	319 NX
Colon	628 NX
Rectum	322 NX
Small intestine	316 NX

Muller glia cells	136 NX
Eye	136 NX

Pancreatic endocrine cells	260 NX
Pancreas	260 NX

Paneth cells	428 NX
Colon	599 NX
Small intestine	428 NX
Rectum	293 NX

Peritubular cells	147 NX
Testis	147 NX

Proximal tubular cells	624 NX
Kidney	624 NX

Rod photoreceptor cells	82 NX
Eye	82 NX

Sertoli cells	188 NX
Testis	188 NX

Smooth muscle cells	260 NX
Heart muscle	395 NX
Pancreas	268 NX
Skin	234 NX
Prostate	199 NX

Spermatocytes	198 NX
Testis	198 NX

Spermatogonia	122 NX
Testis	122 NX

Suprabasal keratinocytes	160 NX
Skin	160 NX

Syncytiotrophoblasts	167 NX
Placenta	167 NX

T-cells	150 NX
Kidney	216 NX
Skin	188 NX
Liver	153 NX
Colon	149 NX
Prostate	109 NX
Lung	81 NX

Undifferentiated cells	389 NX
Colon	519 NX
Rectum	428 NX
Small intestine	372 NX

Urothelial cells	110 NX
Prostate	110 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.