Cell type atlas - LLPH - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

LLPH

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	LLPH
Gene descriptionⁱ Full gene name according to HGNC.	LLP homolog, long-term synaptic facilitation
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	12 NX
Lung	12 NX

Alveolar cells type 2	36 NX
Lung	36 NX

B-cells	61 NX
Kidney	62 NX
Colon	60 NX
Liver	51 NX

Basal glandular cells	45 NX
Prostate	45 NX

Basal keratinocytes	24 NX
Skin	24 NX

Bipolar cells	16 NX
Eye	16 NX

Cardiomyocytes	21 NX
Heart muscle	21 NX

Cholangiocytes	51 NX
Liver	51 NX

Ciliated cells	31 NX
Lung	31 NX

Club cells	53 NX
Lung	53 NX

Collecting duct cells	30 NX
Kidney	30 NX

Cone photoreceptor cells	4 NX
Eye	4 NX

Cytotrophoblasts	54 NX
Placenta	54 NX

Distal tubular cells	56 NX
Kidney	56 NX

Ductal cells	65 NX
Pancreas	65 NX

Early spermatids	30 NX
Testis	30 NX

Endothelial cells	28 NX
Pancreas	54 NX
Testis	39 NX
Placenta	34 NX
Lung	29 NX
Liver	29 NX
Prostate	28 NX
Eye	20 NX
Skin	18 NX
Heart muscle	16 NX

Enterocytes	33 NX
Small intestine	37 NX
Colon	33 NX
Rectum	27 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	62 NX
Pancreas	62 NX

Extravillous trophoblasts	56 NX
Placenta	56 NX

Fibroblasts	33 NX
Lung	43 NX
Placenta	37 NX
Prostate	33 NX
Heart muscle	28 NX
Skin	22 NX

Glandular cells	31 NX
Prostate	31 NX

Granulocytes	88 NX
Colon	101 NX
Lung	74 NX

Hepatocytes	54 NX
Liver	54 NX

Hofbauer cells	57 NX
Placenta	57 NX

Horizontal cells	21 NX
Eye	21 NX

Intestinal endocrine cells	13 NX
Rectum	16 NX
Colon	10 NX

Ito cells	33 NX
Liver	33 NX

Kupffer cells	50 NX
Liver	50 NX

Late spermatids	10 NX
Testis	10 NX

Leydig cells	41 NX
Testis	41 NX

Macrophages	52 NX
Kidney	80 NX
Pancreas	80 NX
Lung	53 NX
Testis	52 NX
Prostate	33 NX
Skin	28 NX

Melanocytes	34 NX
Skin	34 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	79 NX
Pancreas	79 NX

Mucus-secreting cells	24 NX
Colon	33 NX
Small intestine	23 NX
Rectum	22 NX

Muller glia cells	26 NX
Eye	26 NX

Pancreatic endocrine cells	77 NX
Pancreas	77 NX

Paneth cells	35 NX
Small intestine	53 NX
Colon	35 NX
Rectum	31 NX

Peritubular cells	28 NX
Testis	28 NX

Proximal tubular cells	62 NX
Kidney	62 NX

Rod photoreceptor cells	15 NX
Eye	14 NX

Sertoli cells	26 NX
Testis	26 NX

Smooth muscle cells	24 NX
Pancreas	79 NX
Prostate	29 NX
Skin	22 NX
Heart muscle	13 NX

Spermatocytes	78 NX
Testis	78 NX

Spermatogonia	46 NX
Testis	46 NX

Suprabasal keratinocytes	27 NX
Skin	27 NX

Syncytiotrophoblasts	61 NX
Placenta	61 NX

T-cells	42 NX
Kidney	68 NX
Colon	59 NX
Lung	56 NX
Liver	41 NX
Skin	39 NX
Prostate	35 NX

Undifferentiated cells	29 NX
Colon	40 NX
Small intestine	34 NX
Rectum	24 NX

Urothelial cells	46 NX
Prostate	46 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.