Cell type atlas - OLA1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

OLA1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	OLA1
Gene descriptionⁱ Full gene name according to HGNC.	Obg like ATPase 1
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	6

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	33 NX
Lung	33 NX

Alveolar cells type 2	27 NX
Lung	27 NX

B-cells	46 NX
Colon	51 NX
Liver	46 NX
Kidney	31 NX

Basal glandular cells	63 NX
Prostate	63 NX

Basal keratinocytes	56 NX
Skin	56 NX

Bipolar cells	46 NX
Eye	46 NX

Cardiomyocytes	66 NX
Heart muscle	66 NX

Cholangiocytes	33 NX
Liver	33 NX

Ciliated cells	36 NX
Lung	36 NX

Club cells	46 NX
Lung	46 NX

Collecting duct cells	30 NX
Kidney	30 NX

Cone photoreceptor cells	33 NX
Eye	33 NX

Cytotrophoblasts	127 NX
Placenta	127 NX

Distal tubular cells	88 NX
Kidney	88 NX

Ductal cells	131 NX
Pancreas	131 NX

Early spermatids	196 NX
Testis	196 NX

Endothelial cells	42 NX
Placenta	68 NX
Testis	62 NX
Pancreas	54 NX
Lung	53 NX
Prostate	52 NX
Eye	38 NX
Skin	36 NX
Heart muscle	33 NX
Liver	22 NX

Enterocytes	48 NX
Small intestine	64 NX
Rectum	46 NX
Colon	29 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	92 NX
Pancreas	92 NX

Extravillous trophoblasts	86 NX
Placenta	86 NX

Fibroblasts	49 NX
Lung	89 NX
Placenta	82 NX
Skin	47 NX
Prostate	45 NX
Heart muscle	43 NX

Glandular cells	50 NX
Prostate	50 NX

Granulocytes	40 NX
Colon	46 NX
Lung	35 NX

Hepatocytes	24 NX
Liver	24 NX

Hofbauer cells	87 NX
Placenta	87 NX

Horizontal cells	32 NX
Eye	32 NX

Intestinal endocrine cells	68 NX
Colon	68 NX
Rectum	68 NX

Ito cells	20 NX
Liver	20 NX

Kupffer cells	55 NX
Liver	55 NX

Late spermatids	68 NX
Testis	68 NX

Leydig cells	37 NX
Testis	37 NX

Macrophages	51 NX
Testis	77 NX
Prostate	62 NX
Pancreas	59 NX
Skin	51 NX
Lung	47 NX
Kidney	42 NX

Melanocytes	30 NX
Skin	30 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	67 NX
Pancreas	67 NX

Mucus-secreting cells	73 NX
Rectum	87 NX
Small intestine	70 NX
Colon	63 NX

Muller glia cells	44 NX
Eye	44 NX

Pancreatic endocrine cells	99 NX
Pancreas	98 NX

Paneth cells	39 NX
Rectum	76 NX
Small intestine	39 NX
Colon	26 NX

Peritubular cells	48 NX
Testis	48 NX

Proximal tubular cells	106 NX
Kidney	106 NX

Rod photoreceptor cells	29 NX
Eye	29 NX

Sertoli cells	26 NX
Testis	26 NX

Smooth muscle cells	61 NX
Pancreas	89 NX
Prostate	65 NX
Skin	60 NX
Heart muscle	18 NX

Spermatocytes	77 NX
Testis	77 NX

Spermatogonia	35 NX
Testis	35 NX

Suprabasal keratinocytes	56 NX
Skin	56 NX

Syncytiotrophoblasts	89 NX
Placenta	89 NX

T-cells	58 NX
Colon	64 NX
Prostate	61 NX
Kidney	58 NX
Liver	54 NX
Skin	49 NX
Lung	42 NX

Undifferentiated cells	102 NX
Small intestine	127 NX
Colon	87 NX
Rectum	81 NX

Urothelial cells	66 NX
Prostate	66 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.