Cell type atlas - ARHGAP29 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

ARHGAP29

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	ARHGAP29
Gene descriptionⁱ Full gene name according to HGNC.	Rho GTPase activating protein 29
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Glandular cells, Endothelial cells)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Group enriched (non-classical monocyte, intermediate monocyte, classical monocyte)
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in some
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (A-431, hTERT-HME1)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Glandular cells, Endothelial cells)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	48 NX
Lung	48 NX

Alveolar cells type 2	17 NX
Lung	17 NX

B-cells	3 NX
Kidney	18 NX
Colon	3 NX
Liver	1 NX

Basal glandular cells	136 NX
Prostate	136 NX

Basal keratinocytes	21 NX
Skin	21 NX

Bipolar cells	10 NX
Eye	10 NX

Cardiomyocytes	20 NX
Heart muscle	20 NX

Cholangiocytes	26 NX
Liver	26 NX

Ciliated cells	9 NX
Lung	9 NX

Club cells	33 NX
Lung	33 NX

Collecting duct cells	124 NX
Kidney	124 NX

Cone photoreceptor cells	18 NX
Eye	18 NX

Cytotrophoblasts	22 NX
Placenta	22 NX

Distal tubular cells	46 NX
Kidney	46 NX

Ductal cells	71 NX
Pancreas	71 NX

Early spermatids	50 NX
Testis	50 NX

Endothelial cells	271 NX
Heart muscle	393 NX
Skin	361 NX
Placenta	297 NX
Prostate	271 NX
Eye	223 NX
Testis	178 NX
Lung	178 NX
Pancreas	111 NX
Liver	97 NX

Enterocytes	0 NX
Colon	1 NX
Rectum	0 NX
Small intestine	0 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	15 NX
Pancreas	15 NX

Extravillous trophoblasts	90 NX
Placenta	90 NX

Fibroblasts	34 NX
Prostate	114 NX
Heart muscle	97 NX
Skin	42 NX
Lung	33 NX
Placenta	4 NX

Glandular cells	419 NX
Prostate	419 NX

Granulocytes	4 NX
Lung	7 NX
Colon	0 NX

Hepatocytes	51 NX
Liver	51 NX

Hofbauer cells	3 NX
Placenta	3 NX

Horizontal cells	87 NX
Eye	87 NX

Intestinal endocrine cells	0 NX
Colon	0 NX
Rectum	0 NX

Ito cells	177 NX
Liver	177 NX

Kupffer cells	19 NX
Liver	19 NX

Late spermatids	16 NX
Testis	16 NX

Leydig cells	23 NX
Testis	23 NX

Macrophages	6 NX
Prostate	16 NX
Kidney	11 NX
Skin	9 NX
Lung	6 NX
Testis	3 NX
Pancreas	0 NX

Melanocytes	25 NX
Skin	25 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	0 NX
Pancreas	0 NX

Mucus-secreting cells	1 NX
Rectum	1 NX
Colon	1 NX
Small intestine	0 NX

Muller glia cells	95 NX
Eye	95 NX

Pancreatic endocrine cells	37 NX
Pancreas	37 NX

Paneth cells	0 NX
Rectum	0 NX
Colon	0 NX
Small intestine	0 NX

Peritubular cells	21 NX
Testis	21 NX

Proximal tubular cells	48 NX
Kidney	48 NX

Rod photoreceptor cells	81 NX
Eye	81 NX

Sertoli cells	188 NX
Testis	188 NX

Smooth muscle cells	198 NX
Heart muscle	221 NX
Skin	209 NX
Prostate	104 NX
Pancreas	6 NX

Spermatocytes	66 NX
Testis	66 NX

Spermatogonia	124 NX
Testis	124 NX

Suprabasal keratinocytes	15 NX
Skin	15 NX

Syncytiotrophoblasts	12 NX
Placenta	12 NX

T-cells	4 NX
Prostate	13 NX
Skin	9 NX
Kidney	8 NX
Lung	7 NX
Colon	2 NX
Liver	1 NX

Undifferentiated cells	0 NX
Colon	2 NX
Rectum	0 NX
Small intestine	0 NX

Urothelial cells	45 NX
Prostate	45 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.