Cell type atlas - RPLP1 - The Human Protein Atlas

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RPLP1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RPLP1
Gene descriptionⁱ Full gene name according to HGNC.	Ribosomal protein lateral stalk subunit P1
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Plasma proteins Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	3

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Suprabasal keratinocytes)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Suprabasal keratinocytes)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	1757 NX
Lung	1757 NX

Alveolar cells type 2	3079 NX
Lung	3079 NX

B-cells	10545 NX
Liver	11220 NX
Kidney	10377 NX
Colon	1723 NX

Basal glandular cells	15462 NX
Prostate	15462 NX

Basal keratinocytes	21485 NX
Skin	21485 NX

Bipolar cells	611 NX
Eye	611 NX

Cardiomyocytes	1535 NX
Heart muscle	1535 NX

Cholangiocytes	3648 NX
Liver	3648 NX

Ciliated cells	2472 NX
Lung	2472 NX

Club cells	4956 NX
Lung	4956 NX

Collecting duct cells	2150 NX
Kidney	2150 NX

Cone photoreceptor cells	330 NX
Eye	330 NX

Cytotrophoblasts	7737 NX
Placenta	7737 NX

Distal tubular cells	4357 NX
Kidney	4357 NX

Ductal cells	4586 NX
Pancreas	4586 NX

Early spermatids	335 NX
Testis	335 NX

Endothelial cells	5371 NX
Prostate	9791 NX
Skin	7392 NX
Testis	6954 NX
Liver	5916 NX
Placenta	5371 NX
Pancreas	3549 NX
Eye	2140 NX
Lung	1689 NX
Heart muscle	725 NX

Enterocytes	2418 NX
Small intestine	4239 NX
Rectum	2541 NX
Colon	2201 NX

Erythroid cells	3387 NX
Liver	3387 NX

Exocrine glandular cells	6194 NX
Pancreas	6194 NX

Extravillous trophoblasts	10107 NX
Placenta	10107 NX

Fibroblasts	5971 NX
Lung	7945 NX
Prostate	6702 NX
Skin	6117 NX
Placenta	5888 NX
Heart muscle	1175 NX

Glandular cells	9645 NX
Prostate	9645 NX

Granulocytes	2462 NX
Lung	3776 NX
Colon	1148 NX

Hepatocytes	5669 NX
Liver	5669 NX

Hofbauer cells	7196 NX
Placenta	7196 NX

Horizontal cells	353 NX
Eye	353 NX

Intestinal endocrine cells	2817 NX
Rectum	4384 NX
Colon	1251 NX

Ito cells	4602 NX
Liver	4602 NX

Kupffer cells	7393 NX
Liver	7393 NX

Late spermatids	1147 NX
Testis	1147 NX

Leydig cells	7822 NX
Testis	7822 NX

Macrophages	8503 NX
Prostate	12370 NX
Skin	9720 NX
Testis	9041 NX
Kidney	8915 NX
Lung	3810 NX
Pancreas	3643 NX

Melanocytes	8586 NX
Skin	8586 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	10174 NX
Pancreas	10174 NX

Mucus-secreting cells	7224 NX
Rectum	10767 NX
Small intestine	6208 NX
Colon	2933 NX

Muller glia cells	1445 NX
Eye	1445 NX

Pancreatic endocrine cells	6676 NX
Pancreas	6676 NX

Paneth cells	4201 NX
Rectum	7418 NX
Small intestine	4201 NX
Colon	2352 NX

Peritubular cells	4449 NX
Testis	4449 NX

Proximal tubular cells	6345 NX
Kidney	6345 NX

Rod photoreceptor cells	808 NX
Eye	808 NX

Sertoli cells	2490 NX
Testis	2490 NX

Smooth muscle cells	6776 NX
Prostate	8711 NX
Skin	7939 NX
Pancreas	5687 NX
Heart muscle	1086 NX

Spermatocytes	668 NX
Testis	668 NX

Spermatogonia	1530 NX
Testis	1530 NX

Suprabasal keratinocytes	24827 NX
Skin	24827 NX

Syncytiotrophoblasts	7947 NX
Placenta	7947 NX

T-cells	8933 NX
Skin	11544 NX
Prostate	9597 NX
Liver	9218 NX
Kidney	8153 NX
Lung	5726 NX
Colon	1634 NX

Undifferentiated cells	9956 NX
Small intestine	10736 NX
Rectum	9956 NX
Colon	1934 NX

Urothelial cells	14670 NX
Prostate	14670 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.